Nile Red

Product Name: Nile Red
CAS No.: 7385-67-3
Chemical Name: Nile Red
Synonyms: NILE BLUE A OXAZONE;Fluorescent Spectral Standard E, certified;9-(DIETHYLAMINO)-5H-BENZO[A]PHENOXAZIN-5-ONE;nile;NILE RED;nilereddye;Phenoxazone;Oxazine O-17M;Nile Red ,99%;Phenoxazone 9
CBNumber: CB0273873
Molecular Formula: C20H18N2O2
Formula Weight: 318.37
MOL File: 7385-67-3.mol

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Nile Red Property

Melting point:: 203-205 °C(lit.)
Boiling point:: 457.53°C (rough estimate)
Density: 1.1871 (rough estimate)
refractive index: 1.5700 (estimate)
storage temp.: 2-8°C
solubility: methanol: soluble1mg/mL
form: Powder
pka: 4.08±0.20(Predicted)
color: Dark red to maroon
BRN: 279110
Stability:: Stable. Incompatible with strong oxidizing agents.
InChI: InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
InChIKey: VOFUROIFQGPCGE-UHFFFAOYSA-N
SMILES: C12=CC=CC=C1C(=O)C=C1C2=NC2=C(C=C(N(CC)CC)C=C2)O1
CAS DataBase Reference: 7385-67-3(CAS DataBase Reference)
EPA Substance Registry System: 5H-Benzo[a]phenoxazin-5-one, 9-(diethylamino)- (7385-67-3)

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Safety

Safety Statements: 24/25
WGK Germany: 3
F: 8-10
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 72485
Product name: Nile Red
Purity: for microscopy
Packaging: 1g
Price: $709
Updated: 2024/03/01

Sigma-Aldrich

Product number: 19123
Product name: Nile Red
Purity: BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
Packaging: 10mg
Price: $112
Updated: 2024/03/01

TCI Chemical

Product number: N0659
Product name: Nile Red
Packaging: 500mg
Price: $164
Updated: 2024/03/01

TCI Chemical

Product number: N0659
Product name: Nile Red
Packaging: 1g
Price: $270
Updated: 2024/03/01

Sigma-Aldrich

Product number: N3013
Product name: Nile Red
Purity: Technical grade
Packaging: 100mg
Price: $129
Updated: 2024/03/01

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Nile Red Chemical Properties,Usage,Production

Uses

Nile red is a lipophilic stain. It stains intracellular lipid droplets. Nile red is also intensely fluorescent, with a strong yellow-gold emission if included into a lipid-rich environment.

Definition

Nile Red is an organic heterotetracyclic compound that is 5H-benzo[a]phenoxazin-5-one substituted at position 9 by a diethylamino group.

General Description

Nile Red is an uncharged hydrophobic molecule and a benzophenoxazone dye. It functions as a fluorescent probe for intracellular lipids and hydrophobic domains of proteins. This dye is fluorescent in all organic solvents. Its fluorescence colors range from golden yellow to deep red.

Synthesis

Using the 1,3-Naphthalenediol Approach to synthsis Nile red. To a solution of 1,3-naphthalenediol (0.50 g, 3.12 mmol) in anhydrous DMF (25 mL) was added 4-nitroso-N,N-diethylaniline (0.56 g, 3.12 mmol). This reaction mixture was stirred at 80 °C (DrySyn heating block) for 16 h and concentrated under reduced pressure. The crude product was purified by flash chromatography (0?50% EtOAc in hexanes) to obtain Nile Red, which crystallized from hexanes in green crystals (0.80 g, 2.50 mmol). Yield: 80%[1].

storage

Room temperature

References

[1] Mick Hornum*. “Substituted 9-Diethylaminobenzo[a]phenoxazin-5-ones (Nile Red Analogues): Synthesis and Photophysical Properties.” The Journal of Organic Chemistry 86 2 (2020): 1471–1488.

Nile Red Preparation Products And Raw materials

Raw materials

Ethanol 2-Hydroxy-1,4-naphoquinone 3-Diethylaminophenol Nickel Sodium nitrite Diethyl ether 1,4-Naphthoquinone Hydrochloric acid Acetic acid Sodium hydroxide Isopropyl alcohol

Preparation Products

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View Lastest Price from Nile Red manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Nile Red 7385-67-3
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 95%
Supply Ability: 1kg/month
Release date: 2021-05-28

Hebei Weibang Biotechnology Co., Ltd

Product: NILE RED 7385-67-3
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

Hebei Mojin Biotechnology Co., Ltd

Product: NILE RED 7385-67-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-16

7385-67-3, Nile Red Related Search:

m-Anisidine 3-Diethylaminophenol 3-Dimethylaminophenol o-Phenetidine 3-ETHYLAMINOPHENOL INDOPHENOL BLUE N,N-Diethyl-1,4-phenylenediamine Nile Red 3-Dimethylaminoanisole Rifalazil 4-METHOXY-3-BUTEN-2-ONE N-Benzylideneaniline 3-METHOXY-N-METHYLANILINE ETH-(E)-YLIDENE-PHENYL-AMINE 3-ETHOXY-N,N-DIETHYLANILINE 2-PHENYLETHYL PHENYL ETHER Benzoxazine 9-DIETHYLAMINO-2-HYDROXY-5H-BENZ(A)-

NILE BLUE A OXAZONE

NILE RED

9-(DIETHYLAMINO)-5H-BENZO[A]PHENOXAZIN-5-ONE

9-(diethylamino)-5h-benzo[a]phenoxazin-5-on

nile

9-(diethylamino)benzo[a]phenoxazin-5(5H)-one

FLUORESCENCE QY-STANDARD E CERTIFIED

Fluorescent Spectral Standard E, certified

9-(Diethylamino)benzo[a]phenoxazin-5(5H)-on

Nile Red, pure, 99%

9-Diethylamino-benzo[a]phenoxazin-5-one

7-(Diethylamino)-1,2-[1,3]butadieno-3H-phenoxazine-3-one

9-Diethylamino-5H-benzo[a]phenoxazine-5-one

Oxazine O-17M

Phenoxazone

Nile Red,99%,pure

Nile Red ,99%

Nile Red,Nile Blue A Oxazone

9-Diethylaminobenzo[a]phenoxazone

Nile Red, pure, 99% 100MG

Phenoxazone 9

5H-Benzo[a]phenoxazin-5-one,9-(diethylaMino)-

Nile red, Determination of lipids, staining whole tissue

Nile Red, Fluorescent stain for intracellular lipid droplets.

Nile Red *CAS#: 7385-67-3*

Nile Red, 97.5%

NILE RED SUITABLE FOR FLUORESCENCE

nilereddye

Nile red, ≥98%

Nile red, for microscopy

Nile red, puriss

Thioflavin T, Basic Yellow 1

Nile Red, lipophilic stain

7385-67-3

C20H18N2O2

Electroluminescence

BioChemical

Biochemicals and Reagents

Other Fluorescent Labels

Lipophilic and Membrane Probes

Fluorescent Probes, Labels, Particles and Stains

Fluorescence Standards

Fluorescent Indicators and Probes

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marker

Electroluminescence

Functional Materials