ChemicalBook > CAS DataBase List > 1-Boc-5-hydroxyindole

1-Boc-5-hydroxyindole

Product Name
1-Boc-5-hydroxyindole
CAS No.
434958-85-7
Chemical Name
1-Boc-5-hydroxyindole
Synonyms
1-Boc-1H-indol-5-ol;5-AMINOPHTHALIC ACID;1-BOC-5-HYDROXYINDOLE;N-BOC-5-HYDROXYINDOLE;5-hydroxy-1-indolecarboxylate;5-hydroxy-1H-indole-1-carboxylate;tert-butyl 5-hydroxyindole-1-carboxylate;tert-butyl 5-hydroxy-1H-indole-1-carboxylate;1H-Indole-1-carboxylic acid, 5-hydroxy-,1,1-diMethylethyl ester
CBNumber
CB0275347
Molecular Formula
C13H15NO3
Formula Weight
233.26
MOL File
434958-85-7.mol
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1-Boc-5-hydroxyindole Property

Boiling point:
374.5±34.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
9.55±0.40(Predicted)
Appearance
White to off-white Solid
CAS DataBase Reference
434958-85-7(CAS DataBase Reference)
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B656693
Product name
N-Boc-5-Hydroxyindole
Packaging
500mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140244
Product name
tert-Butyl 5-hydroxy-1H-indole-1-carboxylate
Packaging
500mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140244
Product name
tert-Butyl 5-hydroxy-1H-indole-1-carboxylate
Packaging
1g
Price
$105
Updated
2021/12/16
Matrix Scientific
Product number
072860
Product name
N-Boc-5-Hydroxyindole
Purity
95+%
Packaging
1g
Price
$163
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140244
Product name
tert-Butyl 5-hydroxy-1H-indole-1-carboxylate
Packaging
2g
Price
$182
Updated
2021/12/16
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1-Boc-5-hydroxyindole Chemical Properties,Usage,Production

Synthesis

170147-29-2

434958-85-7

General procedure for the synthesis of N-Boc-5-hydroxyindole from tert-butyl 5-(benzyloxy)-1H-indole-1-carboxylate: the product of Example 93A (680 mg, 2.103 mmol) was dissolved in ethanol (20 mL) under nitrogen protection, and 10% palladium carbon (68 mg) and ammonium formate (265 mg, 4.205 mmol) were added. After stirring the reaction for 1 h at room temperature, the reaction mixture was filtered through a 0.45 μm PTFE membrane and the catalyst was washed with methanol. The filtrate was concentrated by rotary evaporator and the resulting residue was dissolved in ethyl acetate (50 mL) and washed sequentially with water (2 × 25 mL) and saturated saline (25 mL). The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to give N-Boc-5-hydroxyindole (475 mg, 96% yield) as a white solid.

References

[1] Patent: WO2007/76034, 2007, A2. Location in patent: Page/Page column 127
[2] Patent: WO2005/51957, 2005, A1. Location in patent: Page/Page column 57

1-Boc-5-hydroxyindole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-Boc-5-hydroxyindole manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Boc-5-hydroxyindole 434958-85-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
1-Boc-5-hydroxyindole 434958-85-7
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500kg
Release date
2018-08-19

434958-85-7, 1-Boc-5-hydroxyindoleRelated Search:


  • N-BOC-5-HYDROXYINDOLE
  • 1-BOC-5-HYDROXYINDOLE
  • 5-AMINOPHTHALIC ACID
  • 1H-Indole-1-carboxylic acid, 5-hydroxy-,1,1-diMethylethyl ester
  • tert-butyl 5-hydroxy-1H-indole-1-carboxylate
  • 5-hydroxy-1H-indole-1-carboxylate
  • 5-hydroxy-1-indolecarboxylate
  • tert-butyl 5-hydroxyindole-1-carboxylate
  • 1-Boc-1H-indol-5-ol
  • 434958-85-7