n-Butyl vinyl ether Property

Melting point:

−92 °C(lit.)

Boiling point:

94 °C(lit.)

Density 

0.774 g/mL at 25 °C(lit.)

vapor density 

3.5 (vs air)

vapor pressure 

42 mm Hg ( 20 °C)

refractive index 

n20/D 1.400(lit.)

Flash point:

15 °F

storage temp. 

2-8°C

solubility 

3g/l

form 

Liquid

color 

Clear

explosive limit

1.2-8.6%(V)

Water Solubility 

3 g/L (20 ºC)

BRN 

1560217

InChIKey

UZKWTJUDCOPSNM-UHFFFAOYSA-N

LogP

3.15 at 20℃

CAS DataBase Reference

111-34-2(CAS DataBase Reference)

NIST Chemistry Reference

Butane, 1-(ethenyloxy)-(111-34-2)

EPA Substance Registry System

Butyl vinyl ether (111-34-2)

Safety

Hazard Codes 

F

Risk Statements 

11-19-2017/11/19

Safety Statements 

9-14-16-33

RIDADR 

UN 2352 3/PG 2

WGK Germany 

2

RTECS 

KN5950000

Autoignition Temperature

437 °F

TSCA 

Yes

HS Code 

2909 19 90

HazardClass 

3

PackingGroup 

II

Hazardous Substances Data

111-34-2(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 10000 mg/kg LD50 dermal Rabbit 3300 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H317May cause an allergic skin reaction

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

n-Butyl vinyl ether Chemical Properties,Usage,Production

Description

Butyl vinyl ether is an extremely flammable,colorless liquid with an ether-like odor. Molecularweight = 100.2; Specific gravity (H2O:1) = 0.8; Boilingpoint = 94℃; Freezing/Melting point = - 112.8℃; Vapordensity (air =1) = 3.5; Flash point = - 9.4℃ (oc);Autoignition temperature = -55℃. Hazard Identification(based on NFPA-704 M Rating System): Health 2,Flammability 3, Reactivity 2. Slightly soluble in water.

Chemical Properties

clear liquid

Uses

Synthesis, copolymerization.

Uses

Butyl Vinyl Ether is a reagent used in organic chemical reactions and the preparation of pharmaceutical compounds used in anticancer therapy. It is also used in the synthesis of potent inhibitors for PDE5. It is also used in the synthesis of copolymers and as an acrylic/vinyl acetate resin comonomer.

Manufacturing Process

(1) It is derived from the reaction of acetylene and butanol. This method requires less equipment and high selectivity. (2) It is obtained by the reaction of acetaldehyde and n-butanol. This method of cleavage from acetal is also a common process for vinyl ethers. Another relatively new method is the reaction of alcohol, ethylene and oxygen in the presence of palladium chloride-copper chloride catalyst to give n-Butyl vinyl ether.

General Description

A liquid. Flash point 0°F. Less dense than water. Vapors heavier than air. May irritate skin and eyes. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Slightly soluble in water; soluble in alcohol and ether. Ethers tend to form unstable peroxides when exposed to oxygen. Ethyl, isobutyl, ethyl tert-butyl, and ethyl tert-pentyl ether are particularly hazardous in this respect. Ether peroxides can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid.

Reactivity Profile

Ethers, such as BUTYL VINYL ETHER can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

Health Hazard

Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Flammability and Explosibility

Highly flammable

Safety Profile

Mildly toxic by ingestion, skin contact, and inhalation. A skin and eye irritant. A very dangerous fire hazard when exposed to heat or flame. To fight fire, use foam, CO2, dry chemical, alcohol foam. Moderately explosive by spontaneous chemical reaction. Can react with oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes. See also ETHERS.

Potential Exposure

Butyl vinyl ether is an extremely flammable, colorless liquid. ether like odor. Molecular weight 5 100.2; specific gravity (H2O:1) 5 0.8; boiling point 5 94C; freezing/melting point 5 2112.8C; vapor density (air 5 1) 5 3.5; flash point 5 29.4C (oc); Autoignition temperature 5 255C. Hazard identification (based on NFP A-704 M Rating System): Health 2; flammability 3; reactivity 1 ?. Slightly soluble in water

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit

storage

Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with butyl vinyl ether you should betrained on its proper handling and storage. Store in tightlyclosed containers in a cool, well-ventilated area. Metalcontainers involving the transfer of this chemical should begrounded and bonded. Drums must be equipped with selfclosing valves, pressure vacuum bungs, and flame arresters.Use only nonsparking tools and equipment, especiallywhen opening and closing containers of this chemical.Sources of ignition, such as smoking and open flames, areprohibited where this chemical is used, handled, or storedin a manner that could create a potential fire or explosionhazard.

Shipping

UN2352 Butyl vinyl ether, stabilized, Hazard Class: 3; Labels: 3—Flammable liquid.

Purification Methods

After five washings with equal volumes of water to remove alcohols (made slightly alkaline with KOH), the ether is dried with sodium and distilled under vacuum, taking the middle fraction [Coombes & Eley J Chem Soc 3700 1957]. Store it over KOH. [Beilstein 1 IV 2052.]

Incompatibilities

Vapors may form explosive mixture with air. Moderately explosive by spontaneous chemical reaction. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids,