Tebufenozide

General Description Chemical Properties Toxicity (to higher animals) Mechanism of Action Control object and using method Attention

Product Name: Tebufenozide
CAS No.: 112410-23-8
Chemical Name: Tebufenozide
Synonyms: MIMIC;rh5992;RoMdan;CONFIRM;Conform;Confirm(TM);MiMic 240LV;MiMic 700WP;ebufenozide;TEBUFENOZIDE
CBNumber: CB0286635
Molecular Formula: C22H28N2O2
Formula Weight: 352.47
MOL File: 112410-23-8.mol

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Tebufenozide Property

Melting point:: 191°; mp 186-188° (Sundaram, 1081)
Density: 1.074±0.06 g/cm3(Predicted)
vapor pressure: 3 x 10 -6 Pa (25 °C)
storage temp.: 0-6°C
solubility: Chloroform: Slightly Soluble,Methanol: Slightly Soluble
form: Solid
Water Solubility: 0.83 mg l^-1 (20 °C)
pka: 10.89±0.46(Predicted)
color: White to off-white
BRN: 7822297
InChI: InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)
InChIKey: QYPNKSZPJQQLRK-UHFFFAOYSA-N
SMILES: C(N(C(C)(C)C)NC(=O)C1=CC=C(CC)C=C1)(=O)C1=CC(C)=CC(C)=C1
LogP: 4.240 (est)
CAS DataBase Reference: 112410-23-8(CAS DataBase Reference)
EPA Substance Registry System: Tebufenozide (112410-23-8)

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Safety

Hazard Codes: N
Risk Statements: 51/53
Safety Statements: 61
RIDADR: UN 3077
WGK Germany: 2
HazardClass: 9
PackingGroup: III
HS Code: 29280000
Hazardous Substances Data: 112410-23-8(Hazardous Substances Data)
Toxicity: LD50 orally in rats, mice: >5000 mg/kg; dermally in rats: >5000 mg/kg; LD50 in honey bees (96 hr, contact): >234 mg/bee; LC50 in mallard duck (8-day dietary): >5000 mg/kg; LC50 in rainbow trout (96 hr): 5.7 mg/l (Heller)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H411Toxic to aquatic life with long lasting effects
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 31652
Product name: Tebufenozide
Purity: PESTANAL
Packaging: 100mg
Price: $198
Updated: 2024/03/01

Cayman Chemical

Product number: 24055
Product name: Tebufenozide
Purity: ≥95%
Packaging: 50mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 24055
Product name: Tebufenozide
Purity: ≥95%
Packaging: 100mg
Price: $152
Updated: 2024/03/01

TRC

Product number: T013200
Product name: Tebufenozide
Packaging: 100mg
Price: $135
Updated: 2021/12/16

AK Scientific

Product number: G709
Product name: Tebufenozide
Packaging: 100mg
Price: $154
Updated: 2021/12/16

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Tebufenozide Chemical Properties,Usage,Production

General Description

Tebufenozide is an ecdysone insecticide, which causes the premature molting of insects by interfering with the normal development of insects. It has high insecticidal activity and high selectivity, being effective in treatment of all lepidopteran larvae, caterpillar, diamondback moth and beet armyworm. It has a strong ovicidal activity, being safe to non-target organisms. Tebfenozide has no irritating effect on the eyes and skin without any teratogenic, carcinogenic and mutagenic effects on higher animals, being of high safety to mammals, birds and natural enemies. It is an ideal insecticide during integrated control.

Chemical Properties

Pure white powder, melting point 191 ℃. Slightly soluble in water and organic solvents; stable to light. It is stable at 5 ° C in pH 7 aqueous solution upon light emission.

Toxicity (to higher animals)

Low toxicity

Mechanism of Action

Tebufenozide is a pro-skinning compound that selectively controls lepidopteran larvae by acting in close association with the descorticophilin receptor protein. During its effect, tebufenozide mimics the action of natural insect pest hormone 20-hydroxy-descorticoid, leading to its premature, deadly peeling.

Control object and using method

It can be used to control a variety of lettuce larvae such as cabbage, apples and other crops. It is effective in the treatment of all instar larvae at drug interval of 14d.

Control Spodoptera exigua, Spodoptera litura, Spodoptera frugiperda, melon field borer and cabbage budworm; apply in the early larvae emergence, spray 1 500 ~ 2 000 times 20% SC.
Control apple leaf roller and peach moth worm, Spray 1000 ~ 2000 times 20% suspension.
Control corn borer and bean curl moth; spray 1000 ~ 2000 times 20% suspension.

Attention

This product is toxic to silkworms, should pay attention to be away from the silkworm area.
This product is generally effective against Plutella xylostella and can be mixed with avermectin.
Spray uniformly; ensure that the contact of liquid with parasites.
It is best to apply pesticide in the evening when controlling beet armyworm.

Uses

Synthetic nonsteroidal ecdysone agonist causing premature molting; novel insect growth regulator specific to lepidopteran species. Insecticide.

Uses

Tebufenozide is used to control lepidopterous larvae on rice, fruit, row crops, nut crops, vegetables and vines and in forestry.

Definition

ChEBI: A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.

Hazard

Low toxicity by ingestion, inhalation, and skin contact.

Agricultural Uses

Insecticide, Insect growth regulator: Tebufenozide is an insect growth regulator that interferes with molting of Lepidopteran larvae. It is used on fruitworm, fireworms, false armyworm, gypsy moth, and spanworms, and is applied pre-harvest. Registered for use in EU countries. Registered for use in the U.S.

Trade name

CONFIRM®; MIMIC®; RH-5992®

Metabolic pathway

Oxidation of ethyl and methyl substituents of the phenyl rings of tebufenozide occurs in soils and plants, to give carboxylic acids, alcohols and a ketone.

Degradation

Tebufenozide was stable at 94 °C for 7 days, stable to light in pH 7 aqueous solution (25 °C) and stable in dark sterile water for 30 days (25 °C). The DT₅₀ in natural pond water, in light, was 30 days (25 °C) (PM). It was stable in acidic and neutral buffer solutions. Hydrolysis was marked in alkaline conditions (DT₅₀ 203 days, pH 10, 20°C). Tebufenozide was stable in sterilised stream water in the dark but degraded in non-sterile water (DT₅₀ 181 days). The insecticide was photodegraded by sunlight (DT₅₀ 83 hours, summer 46°N). The results suggest that microbial degradation and photolysis will be the main routes of tebufenozide dissipation in natural aquatic conditions (Sundaram, 1994).

Tebufenozide Preparation Products And Raw materials

Raw materials

TERT-BUTYL-HYDRAZINE Hexane Ethylbenzene Aluminum chloride Trichloroacetyl chloride Chromatography

Preparation Products

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Tebufenozide Suppliers

Canada 1 China 180 Europe 1 France 2 Germany 2 India 2 Japan 4 Switzerland 1 United Kingdom 3 United States 21 USA 1 Global 218

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
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Aladdin Scientific

Tel: +1-+1(833)-552-7181
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Cayman Chemical Company

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United States Biological

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MedChemExpress

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AccuStandard Inc

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AlliChem, LLC

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Riedel-de Haen AG

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ChemService Inc.

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Waterstone Technology, LLC

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2A PharmaChem USA

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3B Scientific Corporation

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HONEST JOY HOLDINGS LIMITED

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AK Scientific, Inc.

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APAC Pharmaceutical, LLC

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Greatvista Chemicals

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Crescent Chemical Co., Inc.

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Beta Pharma, Inc.

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BOSCHE SCIENTIFIC, LLC

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ChemPacific Corporation

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View Lastest Price from Tebufenozide manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Tebufenozide 112410-23-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-01

Hebei Yanxi Chemical Co., Ltd.

Product: Tebufenozide 112410-23-8
Price: US $30.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-11-13

Hebei Fengjia New Material Co., Ltd

Product: Tebufenozide 112410-23-8
Price: US $2.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-09-06

112410-23-8, TebufenozideRelated Search:

Cyromazine METHOPRENE Tebufenozide 3,5-Dimethylbenzoic acid Formylhydrazine Ethylbenzene Benzoyl hydrazine 4-ETHYLBENZENE-1-CARBOHYDRAZIDE 1,2-DIBENZOYL-1-(T-BUTYL)HYDRAZINE N,N'-DIBENZOYLHYDRAZINE 4-ETHYLBENZYLHYDRAZINE tert-Butyl hydrazine ISOPROPYL-(3-METHYL-BENZYL)-AMINE 3,5-DIMETHYLBENZOHYDRAZIDE N-(3-METHYLPHENYLMETHYL)TERT-BUTYLAMINE TEBUFENOZIDE SOLUTION 100UG/ML IN ACETONITRILE 1ML TEBUFENOZIDE SOLUTION 100UG/ML IN TOLUENE 1ML CHEMPACIFIC 34309

CONFIRM

3,5-dimethylbenzoic acid 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide

MIMIC

TEBUFENOCIDE

TEBUFENOZIDE

rh5992

TEBUFENOZIDE PESTANAL, 100 MG

3,5-DIMETHYLBENZOIC ACID-(1,1-DIMETHYLETHYL)-2-(4-ETHYLBENZOYL)HYDRAZIDE

Benzoic acid, 3,5-dimethyl-, 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide

tebufenozide(ansi,iso,bsi)confirm

N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide

Tebufenozide suspension

Conform

N-tert-butyl-N-(4-ethylbenzoly)-3,5-dimetthyl benzohydrazide

1-tert-Butyl-1-(3,5-diMethylbenzoyl)-2-(4-ethylbenzoyl)hydrazine

Tebufenozide 100mg [112410-23-8]

3,5-Dimethylbenzoic acid N-tert-butyl-N-(4-ethylbenzoyl)hydrazide

616-076-00-9

Confirm(TM)

N-tert-butyl-N'-[(4-ethylphenyl)-oxomethyl]-3,5-dimethylbenzohydrazide

3,5-DiMethyl-1-(1,1-diMethylethyl)-2-(4-ethylbenzoyl)hydrazide Benzoic Acid

MiMic 240LV

MiMic 700WP

RoMdan

ebufenozide

Tebufenozide 0

Tebufenozide Solution, 100ppm

Tebufenozide Solution, 1000ppm

TebufenozideSolutions,100mg/L,1ml

Tebufenozide @100 μg/mL in Methanol

Tebufenozide@1000 μg/mL in Acetonitrile

Tebufenozide Reference Material

{2-methyl-[1,1'-biphenyl]-3-yl}methyl 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane-1-carboxylate

N-(tert-butyl)-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide

Ether fungicide

Tebufenozide-d9 (3,5-dimethylbenzoyl-d9) in acetonitrile

Tebufenozide 10.0 μg/ml Acetonitrile

C17178800 Tebufenozide

L17178800ALTebufenozidE10μg/mLin Acetonitri

Tebufenozide in Methanol

Pyrotinib Impurity 5

112410-23-8

C22H28N2O2

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