VERRUCULOGEN

Product Name: VERRUCULOGEN
CAS No.: 12771-72-1
Chemical Name: VERRUCULOGEN
Synonyms: tr1;T1R1;TRXR1;GPR70;TAS1R1;NA 209A;GRIM-12;MGC9145;TR-1TOXIN;VERRUCOLOGEN
CBNumber: CB0294003
Molecular Formula: C27H33N3O7
Formula Weight: 511.57
MOL File: 12771-72-1.mol

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VERRUCULOGEN Property

Flash point:: 2℃
storage temp.: 2-8°C
form: buffered aqueous solution

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Safety

Hazard Codes: T,Xn,F
Risk Statements: 23/24/25-36-20/21/22-11
Safety Statements: 36/37/39-45-36/37-26-16
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: JH4920000
HS Code: 38220090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SAB2700535
Product name: Anti-TAS1R1 (N-terminal) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 100ul
Price: $368
Updated: 2018/11/23

Sigma-Aldrich

Product number: SAB2700382
Product name: Anti-TAS1R1 (C-terminal) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 100ul
Price: $368
Updated: 2018/11/23

Sigma-Aldrich

Product number: SAB2700382
Product name: Anti-TAS1R1 (C-terminal) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 100 μL
Price: $401
Updated: 2021/03/22

Sigma-Aldrich

Product number: SAB2700535
Product name: Anti-TAS1R1 (N-terminal) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 100 μL
Price: $401
Updated: 2021/03/22

Cayman Chemical

Product number: 11351
Product name: Verruculogen
Purity: ≥95%
Packaging: 1mg
Price: $79
Updated: 2021/03/22

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VERRUCULOGEN Chemical Properties,Usage,Production

Uses

Verruculogen is a tremorgenic mycotoxin, first isolated from Penicillium verruculosum in 1972. The structure was resolved as an indole alkaloid in 1974. Verruculogen is produced by several species of Penicillium and Aspergillus and its presence is a useful taxonomic phenotypic marker. The tremorgenic action of verruculogen is associated with increases in spontaneous glutamate and aspartate release, decreases in GABA levels and, at toxic doses, an increase in the number and decrease in the affinity of DHP receptors in rat cortex. In in vitro guinea pig ileum preparations, verruculogen causes an increase in contractile responses due to electrical field stimulation, attributed to enhancement of acetylcholine from presynaptic nerve terminals. Verruculogen also inhibits Ca2+-activated K+ channels, and is a cell cycle inhibitor blocking division at the M phase.

Uses

Verruculogen is a tremorgenic mycotoxin isolated from species of Penicillium, Aspergillus, and other fungi. It selectively inhibits the activation of Maxi-K potassium channels by charybdotoxin with a K1/2 value of 170 nM. Verruculogen also promotes the release of excitatory neurotransmitters when injected directly into the brain of rats and, at high doses, arrests mouse mammary carcinoma cells in M phase of the cell cycle (MIC = 12.2 μM).[Cayman Chemical]

Definition

ChEBI: An organic heterohexacyclic compound that is a mycotoxic indole alkaloid isolated from Penicillium and Aspergillus species.

VERRUCULOGEN Preparation Products And Raw materials

Raw materials

Preparation Products

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VERRUCULOGEN Suppliers

China 44 Germany 4 Japan 1 Switzerland 2 United Kingdom 7 United States 16 Global 74

Nanjing Shizhou Biology Technology Co.,Ltd

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Fax: 86-21-50328109
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Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
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ChemStrong Scientific Co.,Ltd

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Alta Scientific Co., Ltd.

Tel: 022-65378550- ;022-65378550-
Fax: 022-2532-9655
Email: sales@altascientific.com;marketing@altascientific.com
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Shanghai SuperLan Chemcial Technique Centre

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Lynnchem

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12771-72-1, VERRUCULOGENRelated Search:

N-(1-METHYL-3-PHENYLPROPYL)-N-VALERAMIDE N-PHENYL-3-PIPERIDINAMINE CHEMBRDG-BB 4013122 GLYCINE ANHYDRIDE N,N-Dipropylpropionamide (S)-3-METHYL-2-KETOPIPERAZINE CHEMBRDG-BB 4014926 6-METHOXY-2,3-DIHYDRO-1H-INDOLE N-acetyl-1,6-diaminohexane 4-Methyl-1-piperazineethanamine 3-AMINOPIPERIDINE 2-Aminoethyldiisopropylamine 1-dibutylaminopropan-2-ol 2-(4-METHYL-PIPERIDIN-1-YL)-ETHYLAMINE 2-Ethylpiperazine 2-PIPERIDYLMETHYLAMINE tert-Amyl hydroperoxide 1-Piperazineethanamine,N,4-dimethyl-(9CI)

VERRUCULOGEN

VERRUCULOGEN, PENICILLIUM VERRUCULOSUM

3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth

5h,12h-3,4-dioxa-5a,11a,15a-triazacyclooct(lm)indeno(5,6-b)fluorene-11,15(2h,1

tr1

verruculogentr1

yl-5-(2-methyl-1-propenyl)-,(5r-(5-alpha,10-alpha,10a-alpha,14a-alpha-15b-alp

verruculogen from penicillium*verruculosum

VERRUCULOGEN FROM PENICILLIUM VERRUCULOS

VERRUCOLOGEN

TR-1TOXIN

(5R)-1,10,10a,14,14aα,15bα-Hexahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione

(5R)-2,5,10,10a,11,12,13,14,14aα,15bα-Decahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-3,4-dioxa-5a,11a,15a-triaza-1H-cyclooct[lm]indeno[5,6-b]fluorene-11,15-dione

(5R-(5alpha,10 alpha,10Aalpha,14aalpha,15balpha))-1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5A,11A,15A-triaza cyclooct (1m) indeno (5,6-B)fluorene-11,15(2H,13H)-dione

5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10ar,14as,15bs)-

5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-,(5R-(5-alpha,10-alpha,10A-alpha,14A-alpha-15B-alpha))-

Verruculogenresearch grade

NA 209A

Verruculogen NA 209A TR 1 toxin

Verruculogen solution

GRIM-12

MGC9145

TRXR1

TXNRD1 human

Anti-TAS1R1 (N-terminal) antibody produced in rabbit

GPR70

T1R1

TAS1R1

ANTI-TAS1R1 (CENTER) antibody produced in rabbit

Taste receptor type 1 member 1

Anti-TAS1R1 (C-terminal) antibody produced in rabbit

GWIWVUJHTCZBOP-FCXIIMTCSA-N

5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-, (5R,10S,10aR,14aS,15bS)-

12771-72-1

C27H35N3O7

C27H33N3O7

antibiotic