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3-Acetylthio-2-methylpropanoic acid

Product Name
3-Acetylthio-2-methylpropanoic acid
CAS No.
33325-40-5
Chemical Name
3-Acetylthio-2-methylpropanoic acid
Synonyms
thio-2-methyL;Captopril EP IMpurity G;3-Acetylthioisobutylic acid;3-acetylthioisobutyric acid;B-ACETYLMERCAPTOISOBUTYRIC ACID;(R,S)-β-Acetylmercaptoisobutyrate;BETA-ACETYLMERCAPTOISOBUTYRIC ACID;2-(AcetylthioMethyl)propanoic Acid;3-ACETYLTHIO-2-METHYLPROPIONIC ACID;3-ACETYLTHIO-2-METHYLPROPANOIC ACID
CBNumber
CB0298915
Molecular Formula
C6H10O3S
Formula Weight
162.21
MOL File
33325-40-5.mol
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3-Acetylthio-2-methylpropanoic acid Property

Melting point:
55-57°C
Boiling point:
276.5±23.0 °C(Predicted)
Density 
1.213±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Low-Melting Solid to Solid
pka
4.22±0.10(Predicted)
color 
White to Off-White
LogP
0.880 (est)
CAS DataBase Reference
33325-40-5(CAS DataBase Reference)
EPA Substance Registry System
3-(Acetylthio)-2-methylpropanoic acid (33325-40-5)
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Safety

Hazard Codes 
Xi
HS Code 
2930909899
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
A188775
Product name
3-Acetylthio-2-methylpropionicAcid
Packaging
25g
Price
$2725
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA17189
Product name
3-Acetylthio-2-methylpropanoic acid
Packaging
500mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA17189
Product name
3-Acetylthio-2-methylpropanoic acid
Packaging
1g
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA17189
Product name
3-Acetylthio-2-methylpropanoic acid
Packaging
2g
Price
$180
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA17189
Product name
3-Acetylthio-2-methylpropanoic acid
Packaging
5G
Price
$350
Updated
2021/12/16
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3-Acetylthio-2-methylpropanoic acid Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

3-Acetylthio-2-methylpropionic acid is a key intermediate for Captopril (C175750) and other hypertension drugs.

Purification Methods

Distil the acid under high vacuum and recrystallise it from *C6H6. [Fredga & Mastersson Chem Abstr 38 3616 1944.]

3-Acetylthio-2-methylpropanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Acetylthio-2-methylpropanoic acid Suppliers

Canada 1 China 67 India 9 Japan 1 Switzerland 2 United Kingdom 3 United States 13 Global 96
DKSH Switzerland Ltd.
Tel
--
Fax
--
Country
Switzerland
ProdList
520
Advantage
77
Senn Chemicals AG
Tel
--
Fax
--
Email
swiss@sennchem.com
Country
Switzerland
ProdList
3143
Advantage
71
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View Lastest Price from 3-Acetylthio-2-methylpropanoic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
3-Acetylthio-2-methylpropanoic acid 33325-40-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
3-Acetylthio-2-methylpropanoic acid 33325-40-5
Price
US $1.00/KG
Min. Order
1KG
Purity
98-99.9%
Supply Ability
100kg
Release date
2020-02-03

33325-40-5, 3-Acetylthio-2-methylpropanoic acidRelated Search:

Ethyl levulinate N-ACETYL-L-TYROSINE ETHYL ESTER Calcium thioglycolate 3-Mercaptopropionic acid 2,2-Bis(hydroxymethyl)propionic acid ISOOCTYL 3-MERCAPTOPROPIONATE Folic acid DL-Phenylalanine Acetylacetone Citric acid Isobutyric acid Mercaptoacetic acid POTASSIUM THIOGLYCOLATE ETHYL THIOGLYCOLATE Thiophanate-methyl Ethyl 2-(Chlorosulfonyl)acetate 2-Ethylhexyl mercaptoacetate Dimethyl sulfide

  • 3-(acetylthio)-2-methyl-propanoicaci
  • 3-ACETYLTHIO-2-METHYLPROPANOIC ACID
  • 3-ACETYLTHIO-2-METHYLPROPIONIC ACID
  • BETA-ACETYLMERCAPTOISOBUTYRIC ACID
  • DL-BETA-ACETYLTHIO-ALPHA-METHYLPROPIONIC ACID
  • 3-Acetylthioisobutylic acid
  • 3-ACETYLSULFUR-2-METHYLPROPIONIC ACID
  • 3-acetylthioisobutyric acid
  • 3-Mercapto-2-methylpropionic acid acetate
  • B-ACETYLMERCAPTOISOBUTYRIC ACID
  • 3-ACETYLTHIO-2-METHYLPROPIONIC ACIDCAPTOPRIL
  • 3-(Acetylsulphanyl)-2-methylpropanoic acid, 3-(Acetylthio)-2-methylpropionic acid
  • Propanoic acid,3-(acetylthio)-2-Methyl-
  • (R*)-2-(Acetylthiomethyl)propionic acid
  • (R,S)-β-Acetylmercaptoisobutyrate
  • 3-acetylsulfanyl-2-methylpropanoic acid
  • 3-ethanoylsulfanyl-2-methyl-propanoic acid
  • 2-(AcetylthioMethyl)propanoic Acid
  • 3-Acetylsulfanyl-2-Methylpropionic Acid
  • 3-Mercapto-2-Methylpropionic Acid Acetate (RS)-3-Acetylthio-2-Methylpropionic Acid
  • Captopril EP IMpurity G
  • (2RS)-3-(acetylsulfanyl)-2-methylpropanoic acid
  • Captopril Impurity 7（Captopril EP Impurity G）
  • thio-2-methyL
  • 3-(Acetylthio)-2-methylpropanoic acid (Captopril Impurity)
  • 33325-40-5
  • CH3COSCH2CHCH3COOH
  • Metal Isotopes
  • Captopril
  • Sulfur & Selenium Compounds