3-METHYL-1H-INDAZOLE

Product Name: 3-METHYL-1H-INDAZOLE
CAS No.: 3176-62-3
Chemical Name: 3-METHYL-1H-INDAZOLE
Synonyms: 3-METHYL-1H-INDAZOLE;1H-Indazole, 3-methyl-;Benzenamine,N,N,3,9-tetramethyl-;1-Propanone,1-(3,9-dichlorophenyl)-
CBNumber: CB0303785
Molecular Formula: C8H8N2
Formula Weight: 132.16
MOL File: 3176-62-3.mol

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3-METHYL-1H-INDAZOLE Property

Melting point:: 113°C
Boiling point:: 234.08°C (rough estimate)
Density: 1.1083 (rough estimate)
refractive index: 1.6013 (estimate)
storage temp.: Sealed in dry,Room Temperature
pka: 14.39±0.40(Predicted)

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M336748
Product name: 3-Methyl-1H-indazole
Packaging: 500mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 072395
Product name: 3-Methyl-1H-indazole
Purity: 95+%
Packaging: 5g
Price: $78
Updated: 2021/12/16

Matrix Scientific

Product number: 072395
Product name: 3-Methyl-1H-indazole
Purity: 95+%
Packaging: 1g
Price: $24
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-1-B4
Product name: 3-Methyl-1H-indazole
Packaging: 250mg
Price: $33
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-1-B4
Product name: 3-Methyl-1H-indazole
Packaging: 1g
Price: $100
Updated: 2021/12/16

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3-METHYL-1H-INDAZOLE Chemical Properties,Usage,Production

Description

3-Methyl-1H-indazole is a heterocyclic alkyl compound containing nitrogen and three methyl groups. It is used as an intermediate in the synthesis of other compounds. It has been shown to have anti-inflammatory properties in vitro. It also inhibits neutrophil chemotaxis and may be used to treat inflammatory diseases such as trigeminal neuralgia or heart disease. 3-Methyl-1H-indazole has also been shown to inhibit histamine H3 receptor activity, which may account for its effects on eye diseases and bladder cancer.

Uses

3-Methyl-1H-indazole is an intermediate compound. It can be used as an organic synthesis reagent for the preparation of 3-methyl-1H-indazol-5-amine and 3-methyl-5-nitro-1H-indazole compounds. In addition, the 3-Methyl-1H-indazole derivatives (1a-1d and 2a-2d) have antimicrobial effects, both having antibacterial activity against Bacillus subtilis and Escherichia coli^[1].

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 1817, 1988 DOI: 10.1002/jhet.5570250641
Synthesis, p. 982, 1984

References

[1] FARRUKH SHAIKH. Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives[J]. Intelligent Pharmacy, 2024. DOI:10.1016/j.ipha.2023.09.003.

3-METHYL-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-METHYL-1H-INDAZOLE Suppliers

China 117 Germany 1 India 2 The Netherlands 1 United States 16 Global 137

Energy Chemical

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Jinan Trio PharmaTech Co., Ltd.

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China Langchem Inc.

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View Lastest Price from 3-METHYL-1H-INDAZOLE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-METHYL-1H-INDAZOLE 3176-62-3
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-08

Career Henan Chemical Co

Product: 3-METHYL-1H-INDAZOLE 3176-62-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

3176-62-3, 3-METHYL-1H-INDAZOLERelated Search:

1-Methylindazole-3-carboxylic acid Indazole-3-carboxylic acid Xinidamine Ethychlozate 3-METHYL-1H-INDAZOLE 7-Hydroxygranisetron 1,9-Pyrazoloanthrone Granisetron Hydrochloride Lonidamine Bindarit Losoxantrone GRANISETRON IMPURITY B 7-BROMO-1-METHYL-1H-INDAZOLE 7-BROMO-2-METHYL-2H-INDAZOLE 6-Hydroxy-3-methylindazole 3-(PHENYLMETHYL)-1H-INDAZOLE endo-N-(9-Azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide 1-METHYL-1H-INDAZOLE-3-CARBALDEHYDE

3-METHYL-1H-INDAZOLE

1H-Indazole, 3-methyl-

Benzenamine,N,N,3,9-tetramethyl-

1-Propanone,1-(3,9-dichlorophenyl)-

3176-62-3

Indazole