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Hydroxy-PEG3-Mes

Product Name
Hydroxy-PEG3-Mes
CAS No.
139115-89-2
Chemical Name
Hydroxy-PEG3-Mes
Synonyms
Ms-peg4;CAS_139115-89-2;Hydroxy-PEG3-MS;Hydroxy-PEG3-Mes;3,6,9-Trioxa-2-thiaundecan-11-ol, 2,2-dioxide;2-(2-(2-Hydroxyethoxy)ethoxy)ethyl methanesulfonate
CBNumber
CB03050772
Molecular Formula
C7H16O6S
Formula Weight
228.26
MOL File
139115-89-2.mol
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Hydroxy-PEG3-Mes Property

Boiling point:
398.2±27.0 °C(Predicted)
Density 
1.256±0.06 g/cm3(Predicted)
pka
14.36±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-20704
Product name
Ms-PEG4
Purity
98%
Packaging
1g
Price
$240
Updated
2021/12/16
BroadPharm
Product number
BP-21102
Product name
Hydroxy-PEG3-Ms
Purity
90%
Packaging
1g
Price
$240
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002506
Product name
MS-PEG4
Purity
95.00%
Packaging
1G
Price
$420
Updated
2021/12/16
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Hydroxy-PEG3-Mes Chemical Properties,Usage,Production

Biological Activity

Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Hydroxy-PEG3-Mes Preparation Products And Raw materials

Raw materials

Preparation Products

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139115-89-2, Hydroxy-PEG3-MesRelated Search:


  • Hydroxy-PEG3-Mes
  • Hydroxy-PEG3-MS
  • Ms-peg4
  • CAS_139115-89-2
  • 3,6,9-Trioxa-2-thiaundecan-11-ol, 2,2-dioxide
  • 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl methanesulfonate
  • 139115-89-2
  • C7H16O6S