Azido-PEG10-acid
- Product Name
- Azido-PEG10-acid
- CAS No.
- 1644163-57-4
- Chemical Name
- Azido-PEG10-acid
- Synonyms
- N3-PEG10-COOH;Azido-PEG11-acid;Azido-PEG10-acid;Azido-PEG10-tBu Ester;1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid;N3-PEG10-CH2CH2COOH/Propanoic acid, 3-[(29-azido-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-
- CBNumber
- CB03062335
- Molecular Formula
- C23H45N3O12
- Formula Weight
- 555.62
- MOL File
- 1644163-57-4.mol
Azido-PEG10-acid Property
- solubility
- Soluble in Water, DMSO, DMF
Safety
- HS Code
- 2918999090
N-Bromosuccinimide Price
- Product number
- BP-21820
- Product name
- Azido-PEG10-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- BIPG1111
- Product name
- Azido-PEG10-acid
- Packaging
- 100mg
- Price
- $795
- Updated
- 2021/12/16
- Product number
- 437710
- Product name
- N3-PEG10-CH2CH2COOH
- Purity
- min.95%
- Packaging
- 250mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- B-0903
- Product name
- N3-PEG10-CH2CH2COOH
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $302.5
- Updated
- 2021/12/16
Azido-PEG10-acid Chemical Properties,Usage,Production
Description
Azido-PEG10-acid is a water soluble PEG compound containing an azide group with a terminal carboxylic acid. The azide (N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Azido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG10-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG10-acid Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from Azido-PEG10-acid manufacturers
- Product
- 1-azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid 1644163-57-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- azido-PEG10-Acid 1644163-57-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23