HAMNO
- Product Name
- HAMNO
- CAS No.
- 138736-73-9
- Chemical Name
- HAMNO
- Synonyms
- HAMNO;NSC111847;CID 6335338;MLS000737724;NSC111847,HAMNO;HAMNO (NSC111847);HAMNO >=98% (HPLC);HAMNO, 10 mM in DMSO;HAMNO,inhibit,NSC 111847,NSC-111847,Inhibitor;1-(((2-Hydroxyphenyl)amino)methylene)naphthalen-2(1H)-one
- CBNumber
- CB03146301
- Molecular Formula
- C17H13NO2
- Formula Weight
- 263.29
- MOL File
- 138736-73-9.mol
HAMNO Property
- Boiling point:
- 488.8±45.0 °C(Predicted)
- Density
- 1.392±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF:30.0(Max Conc. mg/mL);113.94(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);113.94(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:30):0.25(Max Conc. mg/mL);0.95(Max Conc. mM) - form
- A crystalline solid
- pka
- 9.98±0.35(Predicted)
- color
- Yellow to orange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 27631
- Product name
- HAMNO
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 27631
- Product name
- HAMNO
- Packaging
- 25mg
- Price
- $420
- Updated
- 2024/03/01
- Product number
- 27631
- Product name
- HAMNO
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 27631
- Product name
- HAMNO
- Packaging
- 10mg
- Price
- $199
- Updated
- 2024/03/01
- Product number
- H105005
- Product name
- HAMNO
- Packaging
- 10mg
- Price
- $75
- Updated
- 2021/12/16
HAMNO Chemical Properties,Usage,Production
Uses
HAMNO, is a novel protein interaction inhibitor of replication protein A (RPA). It has shown to significantly inhibits colony formation when combined with etoposide.
Biological Activity
HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. HAMNO binds the N-terminal domain of RPA70 and inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. HAMNO enhances DNA replication stress in cancer cells and slow tumor growth in vivo.
HAMNO Preparation Products And Raw materials
Raw materials
Preparation Products
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