1,1,1-Trifluoroethyl-PEG5-Propargyl
- Product Name
- 1,1,1-Trifluoroethyl-PEG5-Propargyl
- CAS No.
- 1817735-37-7
- Chemical Name
- 1,1,1-Trifluoroethyl-PEG5-Propargyl
- Synonyms
- 1,1,1-Trifluoroethyl-PEG4-propargyl;1,1,1-Trifluoroethyl-PEG5-Propargyl;3,6,9,12,15-Pentaoxaoctadec-17-yne, 1,1,1-trifluoro-
- CBNumber
- CB03162804
- Molecular Formula
- C13H21F3O5
- Formula Weight
- 314.3
- MOL File
- 1817735-37-7.mol
1,1,1-Trifluoroethyl-PEG5-Propargyl Property
- Boiling point:
- 353.9±37.0 °C(Predicted)
- Density
- 1.142±0.06 g/cm3(Predicted)
N-Bromosuccinimide Price
- Product number
- BP-22903
- Product name
- 1,1,1-Trifluoroethyl-PEG5-Propargyl
- Purity
- 98%
- Packaging
- 100mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- BP-22903
- Product name
- 1,1,1-Trifluoroethyl-PEG5-Propargyl
- Purity
- 98%
- Packaging
- 500mg
- Price
- $650
- Updated
- 2021/12/16
1,1,1-Trifluoroethyl-PEG5-Propargyl Chemical Properties,Usage,Production
Description
1,1,1-Trifluoroethyl-PEG5-Propargyl forms triazole linkage with azides via copper catalyzed azide-alkyne Click Chemistry. The trifluoroethyl group is reactive towards primary amine groups in proteins, antibody and other molecules and surfaces.
Uses
1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1,1,1-Trifluoroethyl-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1,1,1-Trifluoroethyl-PEG5-Propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,1,1-Trifluoroethyl-PEG5-Propargyl manufacturers
- Product
- 1,1,1-Trifluoroethyl-PEG5-propargyl 1817735-37-7
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-27