1,1,1-Trifluoroethyl-PEG4-amine

Product Name: 1,1,1-Trifluoroethyl-PEG4-amine
CAS No.: 1872433-72-1
Chemical Name: 1,1,1-Trifluoroethyl-PEG4-amine
Synonyms: 1,1,1-Trifluoroethyl-PEG4-amine;3,6,9,12-Tetraoxatetradecan-1-amine, 14,14,14-trifluoro-
CBNumber: CB13162801
Molecular Formula: C10H20F3NO4
Formula Weight: 275.27
MOL File: 1872433-72-1.mol

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1,1,1-Trifluoroethyl-PEG4-amine Property

Boiling point:: 315.1±37.0 °C(Predicted)
Density: 1.151±0.06 g/cm3(Predicted)
pka: 8.74±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23123
Product name: 1,1,1-Trifluoroethyl-PEG4-amine
Purity: 98%
Packaging: 250mg
Price: $430
Updated: 2021/12/16

BroadPharm

Product number: BP-23123
Product name: 1,1,1-Trifluoroethyl-PEG4-amine
Purity: 98%
Packaging: 500mg
Price: $680
Updated: 2021/12/16

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1,1,1-Trifluoroethyl-PEG4-amine Chemical Properties,Usage,Production

Description

1, 1, 1-Trifluoroethyl-PEG4-Amine is a PEG linker with a trifluoroethyl and amine moiety. The amine can react with carboxylic acids, activated NHS esters and other carbonyl compounds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media.

Uses

111-Trifluoroethyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

1,1,1-Trifluoroethyl-PEG4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1,1-Trifluoroethyl-PEG4-amine Suppliers

China 13 United States 2 Global 15

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1872433-72-1, 1,1,1-Trifluoroethyl-PEG4-amineRelated Search:

1,1,1-Trifluoroethyl-PEG3-Propargyl 1,1,1-Trifluoroethyl-PEG4-azide 1,1,1-Trifluoroethyl-PEG5-Alcohol 1,1,1-Trifluoroethyl-PEG4-Aminooxy 1,1,1-Trifluoroethyl-PEG2-azide 1,1,1-Trifluoroethyl-PEG5-Propargyl

1,1,1-Trifluoroethyl-PEG4-amine

3,6,9,12-Tetraoxatetradecan-1-amine, 14,14,14-trifluoro-

1872433-72-1

C10H20F3NO4