Cetrorelix acetate

ChemicalBook > CAS DataBase List > Cetrorelix acetate

Product Name: Cetrorelix acetate
CAS No.: 120287-85-6
Chemical Name: Cetrorelix acetate
Synonyms: CETRORELIX;Cetrorelixum;Unii-oon1hfz4ba;CETRORELIX ACID;Cetrorelix acetate;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Cetrorelix?Acetate impurity;Cetrorelix acetate USP/EP/BP;Cetrorelix(Cetrorelix acetate)
CBNumber: CB0316370
Molecular Formula: C70H92ClN17O14
Formula Weight: 1431.04
MOL File: 120287-85-6.mol

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Cetrorelix acetate Property

Melting point:: >259°C (dec.)
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: DMSO (Slightly, Heated), Methanol (Very Slightly)
form: Solid
pka: 9.82±0.15(Predicted)
color: White to Off-White
InChIKey: SBNPWPIBESPSIF-MHWMIDJBSA-N

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Safety

Hazardous Substances Data: 120287-85-6(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Tocris

Product number: 3536
Product name: Cetrorelix acetate
Packaging: 1
Price: $224
Updated: 2021/12/16

Usbiological

Product number: 163043
Product name: Cetrorelix Acetate
Packaging: 5mg
Price: $375
Updated: 2021/12/16

Usbiological

Product number: 254921
Product name: Cetrorelix Acetate
Packaging: 1mg
Price: $480
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364499
Product name: Cetrorelix Acetate
Purity: > 95%
Packaging: 1mg
Price: $695.3
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364499
Product name: Cetrorelix Acetate
Purity: > 95%
Packaging: 5mg
Price: $1480.7
Updated: 2021/12/16

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Cetrorelix acetate Chemical Properties,Usage,Production

Description

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Originator

Asta Medica (Germany)

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-t rosyl, N5-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

brand name

Cetrotide (Serono).

Cetrorelix acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cetrorelix acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Cetrorelix acetate 120287-85-6
Price: US $0.00/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 1000g
Release date: 2021-10-28

Shanghai Affida new material science and technology center

Product: Cetrorelix acetate 120287-85-6
Price: US $0.00-0.00/Box
Min. Order: 1Box
Purity: 99
Supply Ability: 50000KG/month
Release date: 2024-04-12

Hebei Fengjia New Material Co., Ltd

Product: Cetrorelix acetate 120287-85-6
Price: US $6.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-09-10

120287-85-6, Cetrorelix acetateRelated Search:

Tocopheryl acetate Glatiramer acetate Potassium Acetate Triptorelin Butyl acetate Octreotide acetate Sodium acetate Methyl acetate Vinyl acetate Ethyl acetate CETRORELIX TRIFLUOROACETATE CETRORELIX CETRORELIX Pralmorelin Abarelix Argipressine acetate Goserelin acetate DESMOPRESSIN

AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH

Cetrorelix acetate

CETRORELIX

CETRORELIX ACID

CETRIZINEDIHYDROCHLORIDE

N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2

Cetrorelixum

Cetrorelixum [inn-latin]

Unii-oon1hfz4ba

Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 acetate salt

D-AlaninaMide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aMinocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-

Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2

Cetrorelix?Acetate impurity

Cetrorelix acetate USP/EP/BP

Cetrorelix(Cetrorelix acetate)

Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2

120287-85-6

20287-85-6

C70H92ClN17O14

C70H92CIN17O14C2H4O2

Peptide

GYL