ChemicalBook > CAS DataBase List > Cetrorelix acetate

Cetrorelix acetate

Product Name
Cetrorelix acetate
CAS No.
120287-85-6
Chemical Name
Cetrorelix acetate
Synonyms
CETRORELIX;Cetrorelixum;Unii-oon1hfz4ba;CETRORELIX ACID;Cetrorelix acetate;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Cetrorelix?Acetate impurity;Cetrorelix acetate USP/EP/BP;Cetrorelix(Cetrorelix acetate)
CBNumber
CB0316370
Molecular Formula
C70H92ClN17O14
Formula Weight
1431.04
MOL File
120287-85-6.mol
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Cetrorelix acetate Property

Melting point:
>259°C (dec.)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly, Heated), Methanol (Very Slightly)
form 
Solid
pka
9.82±0.15(Predicted)
color 
White to Off-White
InChIKey
SBNPWPIBESPSIF-MHWMIDJBSA-N
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Safety

Hazardous Substances Data
120287-85-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Tocris
Product number
3536
Product name
Cetrorelix acetate
Packaging
1
Price
$224
Updated
2021/12/16
Usbiological
Product number
163043
Product name
Cetrorelix Acetate
Packaging
5mg
Price
$375
Updated
2021/12/16
Usbiological
Product number
254921
Product name
Cetrorelix Acetate
Packaging
1mg
Price
$480
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364499
Product name
Cetrorelix Acetate
Purity
> 95%
Packaging
1mg
Price
$695.3
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364499
Product name
Cetrorelix Acetate
Purity
> 95%
Packaging
5mg
Price
$1480.7
Updated
2021/12/16
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Cetrorelix acetate Chemical Properties,Usage,Production

Description

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Originator

Asta Medica (Germany)

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-t rosyl, N5-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

brand name

Cetrotide (Serono).

Cetrorelix acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cetrorelix acetate manufacturers

Shanghai Affida new material science and technology center
Product
Cetrorelix acetate 120287-85-6
Price
US $0.00-0.00/Box
Min. Order
1Box
Purity
99
Supply Ability
50000KG/month
Release date
2024-04-12
Shanghai Getian Industrial Co., LTD
Product
Cetrorelix acetate 120287-85-6
Price
US $23.00-19.00/box
Min. Order
1box
Purity
99%
Supply Ability
100000box
Release date
2024-05-08
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Cetrorelix acetate 120287-85-6
Price
US $65.00-650.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-21

120287-85-6, Cetrorelix acetateRelated Search:


  • AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH
  • Cetrorelix acetate
  • CETRORELIX
  • CETRORELIX ACID
  • CETRIZINEDIHYDROCHLORIDE
  • N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2
  • Cetrorelixum
  • Cetrorelixum [inn-latin]
  • Unii-oon1hfz4ba
  • Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 acetate salt
  • D-AlaninaMide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aMinocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-
  • Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2
  • Cetrorelix?Acetate impurity
  • Cetrorelix acetate USP/EP/BP
  • Cetrorelix(Cetrorelix acetate)
  • Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2
  • 120287-85-6
  • 20287-85-6
  • C70H92ClN17O14
  • C70H92CIN17O14C2H4O2
  • Peptide
  • GYL