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p-Bromophenoxyacetic acid

Product Name
p-Bromophenoxyacetic acid
CAS No.
1878-91-7
Chemical Name
p-Bromophenoxyacetic acid
Synonyms
4-BROMOPHENOXYACETIC ACID;AKOS BBB/216;AKOS BBS-00001063;IFLAB-BB F1924-0026;p-BroMophenoxyacetic;p-Bromophenoxyacetate;LABOTEST-BB LT00000328;4-BroMophenoxacetic acid;2-(4-bromophenoxy)acetate;P-BROMOPHENOXYACETIC ACID
CBNumber
CB0319740
Molecular Formula
C8H7BrO3
Formula Weight
231.04
MOL File
1878-91-7.mol
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p-Bromophenoxyacetic acid Property

Melting point:
149-153 °C(lit.)
Boiling point:
337.9±17.0 °C(Predicted)
Density 
1.6494 (rough estimate)
refractive index 
1.4730 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
3.09±0.10(Predicted)
color 
White to Almost white
CAS DataBase Reference
1878-91-7(CAS DataBase Reference)
EPA Substance Registry System
Acetic acid, (4-bromophenoxy)- (1878-91-7)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29189900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
549827
Product name
4-Bromophenoxyacetic acid
Purity
95%
Packaging
25g
Price
$165
Updated
2023/01/07
TCI Chemical
Product number
B2746
Product name
4-Bromophenoxyacetic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$23
Updated
2025/07/31
TCI Chemical
Product number
B2746
Product name
4-Bromophenoxyacetic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$65
Updated
2025/07/31
AK Scientific
Product number
J50024
Product name
4-Bromophenoxyacetic Acid
Packaging
1g
Price
$10
Updated
2021/12/16
AK Scientific
Product number
J50024
Product name
4-Bromophenoxyacetic Acid
Packaging
5g
Price
$15
Updated
2021/12/16
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p-Bromophenoxyacetic acid Chemical Properties,Usage,Production

Chemical Properties

White or cream crystalline powder

Uses

4-Bromophenoxyacetic acid may be used as a starting material in the preparation of radioiodinated phenoxyacetic acid derivatives with potential application as radiopharmaceuticals.

General Description

4-Bromophenoxyacetic acid, also known as p-bromophenoxyacetate, is a phenoxyalkanoic acid derivative. It is a chemical elicitor that can induce β-glucuronidase (GUS) activity in rice.

Synthesis

106-41-2

79-11-8

1878-91-7

The general procedure for the synthesis of 4-bromophenoxyacetic acid from 4-bromophenol and chloroacetic acid was as follows: a mixture of NaOH (0.04 mol, 1.60 g), deionized water (20 mL), and ethanol (20 mL) was added to a 150 mL three-necked flask, followed by the slow addition of 4-bromophenol (0.04 mol, 6.92 g). After 20 minutes of reaction under stirring, aqueous sodium chloroacetate solution was added dropwise. The reaction mixture was heated to 105 °C and refluxed for 5 hours. After completion of the reaction, it was cooled to room temperature and the pH of the mixture was adjusted to 1-2 with dilute hydrochloric acid. the precipitate was collected by filtration and washed several times with dilute hydrochloric acid. Finally, the product was purified by recrystallization and dried under vacuum to give 4-bromophenoxyacetic acid as a white solid.

Purification Methods

Crystallise the acid from EtOH or H2O (m 161.4-161.8o). [Hayes & Branch J Am Chem Soc 65 1555 1943, Beilstein 6 III 747, 6 IV 1052.]

References

[1] Luminescence, 2018, vol. 33, # 5, p. 855 - 862
[2] Synthetic Communications, 2004, vol. 34, # 3, p. 377 - 382
[3] Journal of Molecular Structure, 2014, vol. 1074, p. 487 - 495
[4] Journal of Fluorescence, 2015, vol. 25, # 4, p. 849 - 859
[5] Luminescence, 2015, vol. 30, # 5, p. 677 - 685

p-Bromophenoxyacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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p-Bromophenoxyacetic acid Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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64
XiaoGan ShenYuan ChemPharm co,ltd
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15527768836
Email
1791901229@qq.com
Country
China
ProdList
6950
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52
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2766
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Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
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52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
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75
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View Lastest Price from p-Bromophenoxyacetic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
p-Bromophenoxyacetic acid 1878-91-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Bromophenoxyacetic Acid 1878-91-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
p-Bromophenoxyacetic acid 1878-91-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-19

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