7,8-DIHYDRO-L-BIOPTERIN
- Product Name
- 7,8-DIHYDRO-L-BIOPTERIN
- CAS No.
- 6779-87-9
- Chemical Name
- 7,8-DIHYDRO-L-BIOPTERIN
- Synonyms
- BH2;DIHYDROBIOPTERIN;7,8-dihydrobiopterin;Biopterin Impurity 1;Biopterin impurity 6;7,8-DIHYDRO-L-BIOPTERIN;Sapropterin Impurity 18;L-erythro-Dihydrobiopterin;L-erythro-7,8-Dihydrobiopterin;2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-1H-pteridin-4-one
- CBNumber
- CB0320957
- Molecular Formula
- C9H13N5O3
- Formula Weight
- 239.23
- MOL File
- 6779-87-9.mol
7,8-DIHYDRO-L-BIOPTERIN Property
- Melting point:
- >300°C dec.
- Boiling point:
- 470.8±55.0 °C(Predicted)
- Density
- 1.88
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly), DMSO (Slightly)
- pka
- 10.47±0.20(Predicted)
- form
- Solid
- color
- Pale Yellow to Brown
- BRN
- 536551
- Stability:
- Hygroscopic
- InChIKey
- FEMXZDUTFRTWPE-AWFVSMACSA-N
- CAS DataBase Reference
- 6779-87-9
Safety
- WGK Germany
- 3
- F
- 3-10
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 37272
- Product name
- 7,8-Dihydro-L-biopterin
- Purity
- ≥94% (HPLC)
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 37272
- Product name
- 7,8-Dihydro-L-biopterin
- Purity
- ≥94% (HPLC)
- Packaging
- 50mg
- Price
- $470
- Updated
- 2024/03/01
- Product number
- 81882
- Product name
- 7,8-dihydro-L-Biopterin
- Purity
- ≥97%
- Packaging
- 5mg
- Price
- $45
- Updated
- 2024/03/01
- Product number
- 81882
- Product name
- 7,8-dihydro-L-Biopterin
- Purity
- ≥97%
- Packaging
- 10mg
- Price
- $72
- Updated
- 2024/03/01
- Product number
- 81882
- Product name
- 7,8-dihydro-L-Biopterin
- Packaging
- 50mg
- Price
- $330
- Updated
- 2024/03/01
7,8-DIHYDRO-L-BIOPTERIN Chemical Properties,Usage,Production
Description
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Chemical Properties
Yellow Powder
Uses
An oxidation producct of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of G
Uses
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Uses
The reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
Definition
ChEBI: L-erythro-7,8-dihydrobiopterin is a 7,8-dihydrobiopterin in which the 1,2-dihydroxypropyl group has (1R,2S)-configuration; naturally occurring form. It is an enantiomer of a D-erythro-7,8-dihydrobiopterin.
References
[1] shen r, alam a, zhang y. inhibition of gtp cyclohydrolase i by pterins[j]. biochimica et biophysica acta (bba)-general subjects, 1988, 965(1): 9-15.
[2] sugiyama t, levy b d, michel t. tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells[j]. journal of biological chemistry, 2009, 284(19): 12691-12700.