ChemicalBook > CAS DataBase List > Diethyl aminomalonate hydrochloride

Diethyl aminomalonate hydrochloride

Product Name
Diethyl aminomalonate hydrochloride
CAS No.
13433-00-6
Chemical Name
Diethyl aminomalonate hydrochloride
Synonyms
Diethyl 2-aminomalonate;DIETHYL 2-AMINOMALONATE HYDROCHLORIDE;Aminomalonamid;aminomalonate hydrochloride;diethyl 2-aminopropanedioate;AminomaL;onate HydrochL;Diethyl aminomalonat;Amoxapine Impurity 6;Amoxapine Impurity 2 HCl
CBNumber
CB0325376
Molecular Formula
C7H14ClNO4
Formula Weight
211.64
MOL File
13433-00-6.mol
More
Less

Diethyl aminomalonate hydrochloride Property

Melting point:
165-170 °C (dec.)(lit.)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform, DMSO, Water
form 
Crystalline Powder
color 
White to slightly yellow
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
3568037
InChIKey
GLFVNTDRBTZJIY-UHFFFAOYSA-N
CAS DataBase Reference
13433-00-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29224995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D87589
Product name
Diethyl aminomalonate hydrochloride
Purity
98%
Packaging
25g
Price
$39
Updated
2024/03/01
Sigma-Aldrich
Product number
D87589
Product name
Diethyl aminomalonate hydrochloride
Purity
98%
Packaging
10g
Price
$53.6
Updated
2024/03/01
TCI Chemical
Product number
A1016
Product name
Diethyl Aminomalonate Hydrochloride
Packaging
25g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
A1016
Product name
Diethyl Aminomalonate Hydrochloride
Packaging
100g
Price
$42
Updated
2024/03/01
Alfa Aesar
Product number
A13681
Product name
Diethyl aminomalonate hydrochloride, 98%
Packaging
10g
Price
$30.65
Updated
2024/03/01
More
Less

Diethyl aminomalonate hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to slightly yellow crystalline powder

Uses

Diethyl aminomalonate hydrochloride is used as a pharmaceutical intermediate. Diethyl aminomalonate with formaldehyde generates an azomethine ylide which can undergo cycloadditions with 1,2-dipolarophiles to form pyrrolidines.

Synthesis

A solution of 420.0 g of a mixture of diethyl hydroxyiminomalonate and diethyl acetoxyiminomalonate (together 2.0 mol) in 400 ml of ethyl acetate, 40.0 g of anhydrous magnesium sulfate and 12.5 g of palladium on activated charcoal (5 percent by weight of Pd) as hydrogenation catalyst were placed in a 1.5 l pressure reactor equipped with a stirrer. At 30° to 35° C., hydrogen was introduced under a pressure of 20 bar for 80 minutes until the pressure remained constant. The reactor contents were thoroughly mixed by stirring during this process. The hydrogenation mixture was cooled to 20° C. and diluted with 200 ml of ethyl acetate and the mixture of hydrous magnesium sulfate and catalyst was filtered off. The solid which had been separated off was washed three times with a total of 200 ml of ethyl acetate and the wash liquor was combined with the filtrate. Diethyl aminomalonate hydrochloride was precipitated out as a white solid by the introduction of 68 g of dry hydrogen chloride, filtered off, washed with ethyl acetate and dried under a water jet vacuum at 70° C. The yield was 359.6 g (85.1% of theory), the melting point was 165° C. and the purity according to the analytically determined chlorine content was 100%.

Diethyl aminomalonate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Diethyl aminomalonate hydrochloride Suppliers

Americas 1 Belgium 4 CHINA 436 Europe 1 Germany 7 India 32 Japan 3 Slovakia 1 South Korea 3 Switzerland 4 The Netherlands 1 United Kingdom 13 United States 48 Global 554
Xishi Chemical (Shanghai) Co., Ltd.
Tel
021-60499358 13661956116
Fax
+86 (21) 5106-9359
Email
info@cs-pharm.com
Country
China
ProdList
204
Advantage
58
Weifang Siyuan Chemical Co., Ltd.
Tel
0536-8888106 17663601818
Fax
0536-8888106
Email
2354379876@qq.com
Country
China
ProdList
246
Advantage
58
Jiangsu Jingping New Material Technology Co., Ltd.
Tel
18852320356
Email
3437818551@qq.com
Country
China
ProdList
51
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
867
Advantage
58
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19182
Advantage
64
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9511
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8835
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2862
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
Tel
021-34666753 13311639313
Fax
+86-21-34979012
Email
info@shyrchem.com
Country
China
ProdList
571
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1733
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
More
Less

View Lastest Price from Diethyl aminomalonate hydrochloride manufacturers

Changde Changlian Chemical Co., Ltd.
Product
Diethyl aminomalonate hydrochloride 13433-00-6
Price
US $0.00/Kg/Drum
Min. Order
20KG
Purity
98.5%
Supply Ability
100 tons
Release date
2020-07-15
Ningxia Jinhua Chemical Co.,Ltd
Product
Diethyl aminomalonate hydrochloride 13433-00-6
Price
US $0.00/Kg/Drum
Min. Order
20KG
Purity
98.5%
Supply Ability
100 tons
Release date
2020-07-15
Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
Diethyl aminomalonate hydrochloride 13433-00-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98
Supply Ability
1000
Release date
2025-01-09

13433-00-6, Diethyl aminomalonate hydrochlorideRelated Search:

Diethyl methylmalonate Diethyl oxalate Mefenpyr-diethyl Ethyl malonyl chloride Tris(trimethylsilyl)phosphate 2-AMINODIETHYLMALONATE Topotecan hydrochloride Diethyl benzylmalonate Diethyl malonate Ethylene glycol diethyl ether DIETHYL BROMOMALONATE Diethyl fluoromalonate Diethyl dibutylmalonate Dimethyl succinate CARBAMOYL-DL-ASPARTIC ACID N-Sulfo-glucosamine sodium salt Aminomalonic acid Celiprolol

  • AMino Malonic diethyl ester hydrochloride
  • aminomalonate hydrochloride
  • Diethyl 2-aminopropanedioate hydrochloride
  • 1,3-diethyl 2-aminopropanedioate, HCl
  • Diethyl aMinoMalonate hydrochloride (AMinoMalonaMid)
  • Aminomalonamid
  • Diethyl 2-aminomalonate hydrochloride 99%
  • Diethyl aminomalonat
  • Diethyl 2-aminopropane-1,3-dioate hydrochloride
  • Diethyl aMinoMalonate hydrochloride, 98% 25GR
  • 2-Methyl-Malonic acid diethyl ester hydrochloride
  • DIETHYL AMINOMALONATE HYDROCHLORIDE FOR
  • Diethyl aMinoMalonate hydrochloride 98%
  • Diethyl AMinoMalonate Hydrochloride, 95+%
  • Malonic acid, amino-, diethyl ester, hydrochloride
  • Diethyl 3-aminomalonate hydrochloride
  • Two amino malonic acid ethyl ester hydrochloride
  • diethyl 2-aminopropanedioate
  • Propanedioic acid, 2-amino-, 1,3-diethyl ester, hydrochloride (1:1)
  • Diethyl aminomalote hydrochloride
  • AMINOMALONIC ACID DIETHYL ESTER HCL
  • AMINOMALONIC ACID DIETHYL ESTER HYDROCHLORIDE
  • DIETHYL 2-AMINOMALONATE HYDROCHLORIDE
  • DIETHYLAMINO MALONATE HCL
  • DIETHYL AMINOMALONATE HYDROCHLORIDE
  • Diethyl 2-Aminomalonate HCl
  • Propanedioic acid, amino-, diethyl ester, hydrochloride
  • aminomalonic acid dlethyl ester hydrochloride
  • Diethyl aminomalonate hydrochloride, 98%+
  • Diethyl 2-aminomalonate
  • AminomaL
  • onate HydrochL
  • Amoxapine Impurity 6
  • DiethylAminomalonateHydrochloride&gt
  • Diethyl aminmalonic acid hydrochloride
  • Diethylaminomalonathydrochlorid
  • Favipiravir SW(starting materials)
  • TERT-BUTYL4-(2-(2-HYDROXYETHOXY)ETHYL)PIPERAZINE-5-CARBOXYLATE
  • 2-amino-Propanedioic acid 1,3-diethyl ester hydrochloride (1:1)
  • 2-Amino-malonic acid 1,3-diethyl ester HCl
  • Amoxapine Impurity 2 HCl
  • 13433-00-6
  • C7H13NO4xHCl
  • C7H13NO4HCl
  • NH2CH2COOC2H52HCl
  • C7H14ClNO4
  • C7H13NO4ClH
  • AMINE
  • Building Blocks
  • C6 to C7
  • Carbonyl Compounds
  • Organic Building Blocks
  • Esters
  • Building Blocks
  • C6 to C7
  • Carbonyl Compounds
  • Chemical Synthesis
  • Esters