Description
ChemicalBook > CAS DataBase List > (R)-(+)-PROPRANOLOL

(R)-(+)-PROPRANOLOL

Description
Product Name
(R)-(+)-PROPRANOLOL
CAS No.
13071-11-9
Chemical Name
(R)-(+)-PROPRANOLOL
Synonyms
AY 20694;ICI 47319;R-PROPANOLOL;d-Anapriline;R-PROPRANOLOL;(+)-Anapriline;(R)-(+)-PROPRANOLOL;R-(+)-PROPANOLOL HCL;expropranololhydrochloride;d-Propranolol hydrochloride
CBNumber
CB0327608
Molecular Formula
C16H21NO2.ClH
Formula Weight
295.81
MOL File
13071-11-9.mol
More
Less

(R)-(+)-PROPRANOLOL Property

Melting point:
196-198 °C(lit.)
storage temp. 
Store below +30°C.
solubility 
ethanol: 10 mg/mL
form 
Solid
color 
White to Off-White
Water Solubility 
Soluble to 100 mM in water
BRN 
5780490
CAS DataBase Reference
13071-11-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2922 19 00
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P0689
Product name
(R)-(+)-Propranolol hydrochloride
Purity
≥98% (TLC)
Packaging
100mg
Price
$106
Updated
2024/03/01
Sigma-Aldrich
Product number
P0689
Product name
(R)-(+)-Propranolol hydrochloride
Purity
≥98% (TLC)
Packaging
500mg
Price
$424
Updated
2024/03/01
Tocris
Product number
0835
Product name
(R)-(+)-Propranolol hydrochloride
Packaging
100
Price
$87
Updated
2021/12/16
TRC
Product number
P831790
Product name
(R)-(+)-Propranolol hydrochloride
Packaging
5g
Price
$1190
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0001748
Product name
R-PROPANOLOL
Purity
95.00%
Packaging
10G
Price
$2425.5
Updated
2021/12/16
More
Less

(R)-(+)-PROPRANOLOL Chemical Properties,Usage,Production

Description

(R)-Propranolol hydrochloride is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist with high affinity for β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.

Physical properties

(R)-Propranolol's solubility:ethanol: 10 mg/mLDMSO: <14.5 mg/mLH2O: 50 mg/mL (With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)

Uses

less active enantiomer

Uses

The R-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).

Biochem/physiol Actions

Less active enantiomer of propranolol.

Mechanism of action

Pronolol hydrochloride is a non-selective beta-receptor blocker that blocks beta receptors in the myocardium and has antagonistic effects on beta1 and beta2 receptors. Slow down the heart rate, inhibit cardiac contractility and conduction, reduce circulating blood volume, and reduce myocardial oxygen consumption.

storage

Store at RT

Purification Methods

The hydrochloride is recrystallised from n-PrOH or Me2CO. It is soluble in H2O and EtOH but is insoluble in Et2O, *C6H6 or EtOAc. The racemate has m 163-164o, and the free base recrystallises from cyclohexane with m 96o. [Howe & Shanks Nature 210 1336 1966.] The S-isomer (below) is the physiologically active isomer.

(R)-(+)-PROPRANOLOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-(+)-PROPRANOLOL Suppliers

Canada 2 China 66 Germany 4 India 4 South Korea 1 Switzerland 1 Ukraine 1 United Kingdom 6 United States 14 Global 99
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4528
Advantage
56
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shenzhen Chim Biotech Co., Ltd.
Tel
0755-36320761 13692196024
Fax
0755-28364769
Email
sales@chimchem.com
Country
China
ProdList
501
Advantage
55
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10335
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9293
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15503
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10305
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55827
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-61398051 +8613650506873
Email
sales@chemdad.com
Country
China
ProdList
39916
Advantage
58
Shenzhen ruikai de biotechnology co., ltd.
Tel
0755-61348847 17820674378
Fax
0755-21016893
Email
2682116078@qq.com
Country
China
ProdList
7844
Advantage
58
Shanghai Botuo Biotechnology Co., LTD
Tel
16621358918
Fax
QQ:402135374
Email
botuopharma888@163.com
Country
China
ProdList
9215
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
7953
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31163
Advantage
58
Zhengzhou convergence chemical co., LTD
Tel
0371-0371-55153829 18003835034
Fax
18003835034（微信）
Email
2853979819@qq.com
Country
China
ProdList
8648
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223
Email
psaitong@jm-bio.com
Country
China
ProdList
29834
Advantage
58
Hubei Kele Fine Chemical Co., Ltd
Tel
027-59101668 19945030958
Fax
027-59101668
Email
2881924765@qq.com
Country
China
ProdList
7980
Advantage
58
Rhawn Reagent
Tel
400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
1439
Advantage
58
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
6637
Advantage
58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
Tel
+86-027-59232304 15387063101
Email
2881924050@qq.com
Country
China
ProdList
9991
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175-677 18933936954
Email
tianwen.zhan@cato-chem.com
Country
China
ProdList
7712
Advantage
58
Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 15162312715
Email
sales@szzxbio.com
Country
China
ProdList
2999
Advantage
58
Xianning Shen Lan Biomedical Research and Development Co., Ltd.
Tel
18171815831
Email
1341138380@qq.com
Country
China
ProdList
2769
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
17691182729 15529505138
Email
1021@dideu.com
Country
China
ProdList
10011
Advantage
58
Shandong Mopai Biotechnology Co., Ltd
Tel
13053322091 13053322091
Email
admin@mopaikeji.com
Country
China
ProdList
10969
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
5019
Advantage
58
guoyungurui
Tel
18162595016
Email
3287908757@qq.com
Country
China
ProdList
10016
Advantage
58
Hangzhou Bingochem Co., Ltd.
Tel
0571-87632989
Email
sales@bingochem.com
Country
China
ProdList
21673
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12007
Advantage
58
Hubei Kailong Biotechnology Co.,Ltd.
Tel
19526384105
Email
3671394075@qq.com
Country
China
ProdList
2454
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
3674309880
Email
hanfangpharma@126.com
Country
China
ProdList
30968
Advantage
58
career henan chemical co
Tel
+86-0371-86658258
Email
sales@coreychem.com
Country
China
ProdList
29914
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32480
Advantage
60
LEAPCHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43348
Advantage
58
Zibo Hangyu Biotechnology Development Co., Ltd
Tel
+86-0533-2185556 +8617865335152
Email
Mandy@hangyubiotech.com
Country
China
ProdList
11013
Advantage
58
More
Less

View Lastest Price from (R)-(+)-PROPRANOLOL manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
(R)-(+)-PROPRANOLOL 13071-11-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
(R)-(+)-PROPRANOLOL 13071-11-9
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

13071-11-9, (R)-(+)-PROPRANOLOLRelated Search:

(R)-4-Hydroxy Propranolol Hydrochloride,(S)-4-Hydroxy Propranolol Hydrochloride (R)-(+)-PROPRANOLOL PROPRANOLOL H+D409CL USP,DL-Propranolol hydrochloride, (±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride Propranolol Hydrochloride for pharmaceutical raw materials L-(-)-Propranolol hydrochloride,l-Propranolol chlorhydrate,l-Propranolol hydrochloride Propanolol 4-Hydroxy Propranolol b-D-Glucuronide,4-Hydroxy Propranolol -D-Glucuronide rac Propranolol -D-Glucuronide Sodium Salt,propranolol glucuronide,rac Propranolol b-D-Glucuronide Sodium Salt (S)-4-Hydroxy Propranolol (+/-)-4Hydroxy Propranolol-d7 Sulfate 5-Hydroxy Propranolol-d5 rac 7-Hydroxy Propranolol O-isovaleryl propranolol (2S)-Propranolol,l-Propranolol Propranolol hydrochloride for performance test (R)-4-Hydroxy Propranolol 4-HYDROXY PROPRANOLOL-D5 GLUCURONIDE rac 4-Hydroxy Propranolol-d7 -D-Glucuronide

  • R-PROPANOLOL
  • R-(+)-PROPANOLOL HCL
  • 2R-(+)-Propanolol hydrochloride≥ 95% (GCMS)
  • (R)-(+)-Propanolol hydrochloride for synthesis
  • 2R-(+)-PROPANOLOL HYDROCHLORIDE
  • 2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2R)-
  • (+)-Anapriline
  • 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, hydrochloride, (+)- (8CI)
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2R)- (9CI)
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (R)-
  • AY 20694
  • d-Anapriline
  • d-Propranolol hydrochloride
  • ICI 47319
  • R-(+)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride
  • (R)-(+)-PROPANOLOL HYDROCHLORIDE
  • (R)-(+)-PROPRANOLOL
  • R-PROPRANOLOL
  • (R)-(+)-PROPRANOLOL HYDROCHLORIDE
  • (R)-PROPRANOLOL HYDROCHLORIDE
  • (R)-(+)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE
  • (R)-(+)-1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
  • (R)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
  • Dexpropranolol hydrochloride
  • (R)-(+)-Propranolol hydrochloride,(R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
  • (R)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride
  • (R)-(+)-PROPANOLOL HYDROCHLORIDE 99+%
  • (R)-1-(isopropylaMino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
  • (2R)-1-(1-naphthalenyloxy)-3-(propan-2-ylamino)-2-propanol hydrochloride
  • (R)-(+)-PROPANOLOL HYDROCHLORIDE FOR SYN
  • expropranololhydrochloride
  • Inhibitor,enantiomer,Beta Receptor,(R)-Propranolol,Adrenergic Receptor,β-adrenoceptor,cardiac arrhythmias,(R)Propranolol hydrochloride,(R) Propranolol hydrochloride,inhibit
  • Flumiclorac-pentyl Impurity 11
  • 13071-11-9
  • C16H21NOSHCl
  • C10H7OCH2CHOHCH2NHCHCH32HCl
  • Organic Building Blocks
  • Amino Alcohols
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals