(S)-(-)-PROPRANOLOL HYDROCHLORIDE
- Product Name
- (S)-(-)-PROPRANOLOL HYDROCHLORIDE
- CAS No.
- 4199-10-4
- Chemical Name
- (S)-(-)-PROPRANOLOL HYDROCHLORIDE
- Synonyms
- S-PROPANOLOL;S(-)-PROPRANOLOL HCL;S-(-)-PROPANOLOL HCL;l-Propranolol chlorhydrate;l-Propranolol hydrochloride;(S)-PROPRANOLOL HYDROCHLORIDE;Levopropranolol hydrochloride;2S-(-)-PROPANOLOL HYDROCHLORIDE;L-(-)-Propranolol hydrochloride;(S)-(-)-PROPRANOLOL HYDROCHLORIDE
- CBNumber
- CB4455695
- Molecular Formula
- C16H22ClNO2
- Formula Weight
- 295.8
- MOL File
- 4199-10-4.mol
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Property
- Melting point:
- 193-195 °C(lit.)
- storage temp.
- 2-8°C
- solubility
- ethanol: 10 mg/mL
- form
- powder
- color
- White to off-white
- optical activity
- [α]25/D 25.5°, c = 1.0 in ethanol(lit.)
- Water Solubility
- Soluble to 100 mM in water
- BRN
- 3574966
- InChIKey
- ZMRUPTIKESYGQW-UQKRIMTDSA-N
- CAS DataBase Reference
- 4199-10-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- P8688
- Product name
- (S)-(?)-Propranolol hydrochloride
- Purity
- ≥98% (TLC), powder
- Packaging
- 100mg
- Price
- $111
- Updated
- 2024/03/01
- Product number
- P8688
- Product name
- (S)-(?)-Propranolol hydrochloride
- Purity
- ≥98% (TLC), powder
- Packaging
- 500mg
- Price
- $449
- Updated
- 2024/03/01
- Product number
- 17291
- Product name
- (S)-(-)-Propranolol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 17291
- Product name
- (S)-(-)-Propranolol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 17291
- Product name
- (S)-(-)-Propranolol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $161
- Updated
- 2024/03/01
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Chemical Properties,Usage,Production
Description
(S)-(-)-Propranolol is the active enantiomer of propranolol, a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. It is also a non-specific serotonin receptor antagonist. Propanolol was one of the first β-adrenergic receptor blockers to be widely used in clinical practice for the treatment of hypertension, angina pectoris, and cardiac ischemia.
Chemical Properties
(S)-(-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
Uses
Antihypertensor;Beta-adrenergic blocking agent
Uses
The S-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
Uses
active enantiomer, 5-HT1 receptor antagonist
Biological Activity
More active enantiomer of the β -adrenoceptor antagonist propranolol ((RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride ).
Biochem/physiol Actions
(S)-(?)-Propranolol hydrochloride is biologically active enantiomer. It acts as β1 receptor antagonist in thalamocortical neurons. (S)-(?)-Propranolol hydrochloride elicits its inhibitory function on the β1 adrenoceptor in trigeminovascular pain pathway and serves as a preventive medicine in migraine.
storage
Store at RT
Purification Methods
The (+)-salt is the active isomer which blocks isoprenaline tachycardia and is a -adrenergic blocker. [Leclerc et al. Trends Pharmacol Sci 2 18 1981, Howe & Shanks Nature 210 1336 1966.]
(S)-(-)-PROPRANOLOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-(-)-PROPRANOLOL HYDROCHLORIDE manufacturers
- Product
- (S)-(-)-Propranolol hydrochloride 4199-10-4
- Price
- US $1.00-45.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-01
- Product
- (S)-(-)-PROPRANOLOL HYDROCHLORIDE 4199-10-4
- Price
- US $166.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 2000KG
- Release date
- 2021-06-04