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Methyltetrazine-NHS Ester

Product Name
Methyltetrazine-NHS Ester
CAS No.
1644644-96-1
Chemical Name
Methyltetrazine-NHS Ester
Synonyms
Methyltetrazine-NHS Ester;Methyltetrazine-Ph-NHS ester;Methyltetrazine-NHS ester >=95%;Methyltetrazine-NHS Ester (CCT-1128);2,5-dioxopyrrolidin-1-yl 2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl)acetate;2,5-Dioxo-1-pyrrolidinyl 2-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]acetate;Benzeneacetic acid, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB03345049
Molecular Formula
C15H13N5O4
Formula Weight
327.29
MOL File
1644644-96-1.mol
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Methyltetrazine-NHS Ester Property

Boiling point:
563.1±60.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
1.37±0.10(Predicted)
form 
Solid
color 
Purple to purplish red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900914
Product name
Methyltetrazine-NHS ester
Purity
≥95%
Packaging
100MG
Price
$271
Updated
2025/07/31
TCI Chemical
Product number
M3494
Product name
Methyltetrazine-NHS Ester
Packaging
25MG
Price
$140
Updated
2025/07/31
Iris Biotech GmbH
Product number
RL-2320
Product name
MeTz-PhAc-NHS
Packaging
25mg
Price
$229.5
Updated
2021/12/16
Chem-Impex
Product number
35087
Product name
Methyltetrazine-NHSester,95%(HPLC)
Purity
95%(HPLC)
Packaging
100MG
Price
$268.8
Updated
2021/12/16
BroadPharm
Product number
BP-22429
Product name
Methyltetrazine-NHSester
Purity
95%
Packaging
25mg
Price
$95
Updated
2021/12/16
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Methyltetrazine-NHS Ester Chemical Properties,Usage,Production

Description

Methyltetrazine-NHS Ester is a NHS actived building block containing a methyltetrazine group. It can react with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).

Uses

Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

IC 50

Alkyl/ether

Methyltetrazine-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyltetrazine-NHS Ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Methyltetrazine-NHS ester 1644644-96-1
Price
US $0.00/mg
Min. Order
100mg
Purity
>99.00%
Supply Ability
1g
Release date
2024-03-20

1644644-96-1, Methyltetrazine-NHS EsterRelated Search:


  • Methyltetrazine-NHS Ester
  • Methyltetrazine-NHS ester >=95%
  • Methyltetrazine-Ph-NHS ester
  • Benzeneacetic acid, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
  • Methyltetrazine-NHS Ester (CCT-1128)
  • 2,5-Dioxo-1-pyrrolidinyl 2-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]acetate
  • 2,5-dioxopyrrolidin-1-yl 2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl)acetate
  • 1644644-96-1