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Methyltetrazine-PEG4-NHS Ester

Product Name
Methyltetrazine-PEG4-NHS Ester
CAS No.
1802907-92-1
Chemical Name
Methyltetrazine-PEG4-NHS Ester
Synonyms
Mtz-PEG5-NHS;Methyltetrazine-PEG4-NHS Ester;Methyltetrazine-PEG4-NHS ester >=95%;Methyltetrazine-PEG4-NHS Ester (CCT-1069);2,5-dioxopyrrolidin-1-yl 1-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oate;Propanoic acid, 3-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB03345054
Molecular Formula
C24H31N5O9
Formula Weight
533.53
MOL File
1802907-92-1.mol
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Methyltetrazine-PEG4-NHS Ester Property

Boiling point:
697.9±65.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
-20°C
form 
powder or crystals
pka
1.67±0.10(Predicted)
color 
Purple to purplish red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900894
Product name
Methyltetrazine-PEG4-NHS ester
Purity
≥95%
Packaging
50MG
Price
$374
Updated
2023/06/20
TCI Chemical
Product number
M3468
Product name
Methyltetrazine-PEG4-NHS Ester
Packaging
50MG
Price
$117
Updated
2025/07/31
TCI Chemical
Product number
M3468
Product name
Methyltetrazine-PEG4-NHS Ester
Packaging
200MG
Price
$288
Updated
2025/07/31
TCI Chemical
Product number
M3468
Product name
Methyltetrazine-PEG4-NHS Ester
Packaging
1G
Price
$855
Updated
2025/07/31
Iris Biotech GmbH
Product number
RL-2330
Product name
MeTz-PEG(4)-NHS
Packaging
100mg
Price
$864
Updated
2021/12/16
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Methyltetrazine-PEG4-NHS Ester Chemical Properties,Usage,Production

Description

Methyltetrazine-PEG5-NHS Ester is a click chemistry crosslinker containing a methyltetrazine group. THe hydrophilic PEG spacer improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. Methyltetrazine enable click chemistry with TCO (trans-cycloctene).

Uses

Methyltetrazine-PEG4-NHS ester is a crosslinker with enhanced stability and water solubility. This crosslinker has an NHS ester that can be reacted with a primary amine and a methyltetrazine that is reactive with trans-cyclooctenes. Methyltetrazine-PEG4-NHS ester is one of the most stable tetrazines commercially available. In addition to stabilization provided by the electron donating methyl group, the electron donating alkoxy substituent on the aromatic ring further improves the stability of methyltetrazine-PEG4-NHS ester. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

IC 50

PEGs

Methyltetrazine-PEG4-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyltetrazine-PEG4-NHS Ester Suppliers

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View Lastest Price from Methyltetrazine-PEG4-NHS Ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Methyltetrazine-PEG4-NHS ester 1802907-92-1
Price
US $0.00/mg
Min. Order
25mg
Purity
>99.00%
Supply Ability
250mg
Release date
2024-03-20

1802907-92-1, Methyltetrazine-PEG4-NHS EsterRelated Search:


  • Methyltetrazine-PEG4-NHS Ester
  • Methyltetrazine-PEG4-NHS ester >=95%
  • Propanoic acid, 3-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • 2,5-dioxopyrrolidin-1-yl 1-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oate
  • Mtz-PEG5-NHS
  • Methyltetrazine-PEG4-NHS Ester (CCT-1069)
  • 1802907-92-1
  • C24H31N5O9