CHOLIC-2,2,4,4-D4 ACID

Product Name: CHOLIC-2,2,4,4-D4 ACID
CAS No.: 116380-66-6
Chemical Name: CHOLIC-2,2,4,4-D4 ACID
Synonyms: Cholic-d4 Acid;2H4]-Cholic Acid;Cholic acid-2,2,4,4-d;Cholic Acid -[d4] (Solution);Cholic Acid-d4 MaxSpec? Standard;CHOLICACID(2,2,4,4-D4) IN METHANOL;5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4;CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
CBNumber: CB0334837
Molecular Formula: C24H36D4O5
Formula Weight: 412.6
MOL File: 116380-66-6.mol

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CHOLIC-2,2,4,4-D4 ACID Property

Melting point:: 200-201°C (lit.)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
form: Solid
color: White to Off-White

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P307+P311IF exposed: call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 614149
Product name: Cholic acid-2,2,4,4-d
Purity: 98 atom % D, 98% (CP)
Packaging: 500mg
Price: $1670
Updated: 2024/03/01

Cayman Chemical

Product number: 20849
Product name: Cholic Acid-d4
Purity: ≥95%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 20849
Product name: Cholic Acid-d4
Purity: ≥95%
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 20849
Product name: Cholic Acid-d4
Purity: ≥95%
Packaging: 10mg
Price: $223
Updated: 2024/03/01

TRC

Product number: C432603
Product name: CholicAcid-d4
Packaging: 50mg
Price: $470
Updated: 2021/12/16

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CHOLIC-2,2,4,4-D4 ACID Chemical Properties,Usage,Production

Description

Cholic acid-d₄ is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.

Uses

Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.

Definition

ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.

CHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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CHOLIC-2,2,4,4-D4 ACID Suppliers

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116380-66-6, CHOLIC-2,2,4,4-D4 ACIDRelated Search:

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Cholic-d4 Acid

Cholic acid-2,2,4,4-d

5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4

CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL

Cholic Acid -[d4] (Solution)

Cholic Acid-d4 MaxSpec? Standard

2H4]-Cholic Acid

CHOLICACID(2,2,4,4-D4) IN METHANOL

116380-66-6

C24H36D4O5

Steroids & Hormones - 13C & 2H