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4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-

Product Name
4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
CAS No.
1289942-55-7
Chemical Name
4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
Synonyms
EZ-422;Enzalutamide Impurity W;Enzalutamide Impurity 26;4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-;Benzamide, 4-[[2-[[4-cyano-3-(trifluoromethyl)phenyl]amino]-1,1-dimethyl-2-oxoethyl]amino]-2-fluoro-N-methyl-
CBNumber
CB03371808
Molecular Formula
C20H18F4N4O2
Formula Weight
422.38
MOL File
1289942-55-7.mol
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4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Property

Boiling point:
616.2±55.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13?+-.0.70(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C988198
Product name
4-[[2-[[4-Cyano-3-(trifluoromethyl)phenyl]amino]-1,1-dimethyl-2-oxoethyl]amino]-2-fluoro-N-methyl-benzamide
Packaging
1mg
Price
$65
Updated
2021/12/16
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4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Chemical Properties,Usage,Production

Uses

4-[[2-[[4-Cyano-3-(trifluoromethyl)phenyl]amino]-1,1-dimethyl-2-oxoethyl]amino]-2-fluoro-N-methyl-benzamide is an impurity of Enzalutamide (M199800), an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.

4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Suppliers