N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester)

Product Name: N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester)
CAS No.: 2093153-97-8
Chemical Name: N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester)
Synonyms: HUN 53978;N-(Amino-PEG4)-N-bis(PEG4-Boc);N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester);N-(Amino-PEG4)-N-bis(PEG4-tert-butyl Ester);Di-tert-butyl 16-(14-amino-3,6,9,12-tetraoxatetradecyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate;4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-, 1,31-bis(1,1-dimethylethyl) ester
CBNumber: CB03373675
Molecular Formula: C40H80N2O16
Formula Weight: 845.07
MOL File: 2093153-97-8.mol

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N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) Property

Boiling point:: 769.1±55.0 °C(Predicted)
Density: 1.079±0.06 g/cm3(Predicted)
pka: 8.74±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23525
Product name: N-(Amino-PEG4)-N-bis(PEG4-t-butylester)
Purity: 98%
Packaging: 250mg
Price: $650
Updated: 2021/12/16

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N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) Chemical Properties,Usage,Production

Description

N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) is a branched PEG reagent containing an amino group with two t-butyl esters. The amino groups is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) Suppliers

China 20 United States 2 Global 22

Bide Pharmatech Ltd.

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2093153-97-8, N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester)Related Search:

Biotin-PEG36-PFP ester N-(Amino-PEG3)-N-bis(PEG4-Boc) BocNH-PEG5-acid Biotin-PEG6-t-butyl ester FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-[2-T-BOC-AMINOETHOXY]ETHOXY]ETHYL BROMIDE t-Boc-Aminooxy-PEG2-CH2CO2H N-Boc-PEG4-bromide Mal-amido-PEG7-acid Fmoc-NH-PEG12-CH2COOH

N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester)

N-(Amino-PEG4)-N-bis(PEG4-Boc)

4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-, 1,31-bis(1,1-dimethylethyl) ester

HUN 53978

Di-tert-butyl 16-(14-amino-3,6,9,12-tetraoxatetradecyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate

N-(Amino-PEG4)-N-bis(PEG4-tert-butyl Ester)

2093153-97-8

C40H80N2O16