N-(Amino-PEG3)-N-bis(PEG4-Boc)

Product Name: N-(Amino-PEG3)-N-bis(PEG4-Boc)
CAS No.: 2353409-57-9
Chemical Name: N-(Amino-PEG3)-N-bis(PEG4-Boc)
Synonyms: N-(Amino-PEG3)-N-bis(PEG4-Boc);N-(Amino-PEG3)-N-bis(PEG4-t-butyl ester);Di-tert-butyl 16-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate;4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-, 1,31-bis(1,1-dimethylethyl) ester;tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl-[2-[2-[2-[2-(3-tert-butoxy-3-oxo-propoxy)ethoxy]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CBNumber: CB08054760
Molecular Formula: C38H76N2O15
Formula Weight: 801.01
MOL File: 2353409-57-9.mol

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N-(Amino-PEG3)-N-bis(PEG4-Boc) Property

Boiling point:: 743.7±55.0 °C(Predicted)
Density: 1.076±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 8.74±0.10(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24287
Product name: N-(Amino-PEG3)-N-bis(PEG4-t-butylester)
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-24287
Product name: N-(Amino-PEG3)-N-bis(PEG4-t-butylester)
Purity: 98%
Packaging: 250mg
Price: $650
Updated: 2021/12/16

BroadPharm

Product number: BP-24287
Product name: N-(Amino-PEG3)-N-bis(PEG4-t-butylester)
Purity: 98%
Packaging: 500mg
Price: $980
Updated: 2021/12/16

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N-(Amino-PEG3)-N-bis(PEG4-Boc) Chemical Properties,Usage,Production

Description

N-(Amino-PEG3)-N-bis(PEG4-t-butyl ester) is a PEG linker that can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions.

Uses

N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Amino-PEG3)-N-bis(PEG4-Boc) Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Amino-PEG3)-N-bis(PEG4-Boc) Suppliers

China 21 United States 3 Global 24

Xi'an Confluore Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

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View Lastest Price from N-(Amino-PEG3)-N-bis(PEG4-Boc) manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-(Amino-PEG3)-N-bis(PEG4-Boc) 2353409-57-9
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

2353409-57-9, N-(Amino-PEG3)-N-bis(PEG4-Boc)Related Search:

Biotin-PEG36-PFP ester BocNH-PEG5-acid Biotin-PEG6-t-butyl ester FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-[2-T-BOC-AMINOETHOXY]ETHOXY]ETHYL BROMIDE t-Boc-Aminooxy-PEG2-CH2CO2H N-Boc-PEG4-bromide N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) Mal-amido-PEG7-acid Fmoc-NH-PEG12-CH2COOH

N-(Amino-PEG3)-N-bis(PEG4-Boc)

N-(Amino-PEG3)-N-bis(PEG4-t-butyl ester)

tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl-[2-[2-[2-[2-(3-tert-butoxy-3-oxo-propoxy)ethoxy]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-, 1,31-bis(1,1-dimethylethyl) ester

Di-tert-butyl 16-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate

2353409-57-9