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BocNH-PEG5-acid

Product Name
BocNH-PEG5-acid
CAS No.
890152-41-7
Chemical Name
BocNH-PEG5-acid
Synonyms
BocNH-PEG5-acid;BocNH-P5-CH2CO2H;NHBoc-PEG5-CH2COOH;T-boc-n-amido-peg5-ch2co2h;t-boc-N-amido-PEG5-acetic acid;17-(Boc-amino)-3,6,9,12,15-pentaoxaheptadecan-1-oic Acid;2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid;17-{[(tert-butoxy)carbonyl]amino}-3,6,9,12,15-pentaoxaheptadecanoic acid;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(1,1-dimethylethyl) ester;BocNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(1,1-dimethylethyl) ester
CBNumber
CB05430550
Molecular Formula
C17H33NO9
Formula Weight
395.45
MOL File
890152-41-7.mol
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BocNH-PEG5-acid Property

Boiling point:
526.2±50.0 °C(Predicted)
Density 
1.136±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO : 100 mg/mL (252.88 mM; Need ultrasonic)
pka
3.39±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902683
Product name
BocNH-PEG5-acid
Packaging
250MG
Price
$301
Updated
2024/03/01
Sigma-Aldrich
Product number
902683
Product name
BocNH-PEG5-acid
Packaging
1G
Price
$925
Updated
2024/03/01
Chemenu
Product number
CM327825
Product name
2-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]aceticacid
Purity
95%+
Packaging
5g
Price
$1562
Updated
2021/12/16
Acrotein
Product number
B-0896
Product name
BocNH-PEG5-CH2COOH
Purity
97%
Packaging
0.5g
Price
$302.5
Updated
2021/12/16
Acrotein
Product number
B-0896
Product name
BocNH-PEG5-CH2COOH
Purity
97%
Packaging
1g
Price
$458.33
Updated
2021/12/16
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BocNH-PEG5-acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG5-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG5-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

BocNH-PEG5-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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BocNH-PEG5-acid Suppliers

PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498 19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
485
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28810
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1388
Advantage
58
Alfa Chemistry
Tel
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
Advantage
58
Changzhou Yinghao Technology Development Co., Ltd
Tel
15151934985
Email
sales@yingsapharm.com
Country
China
ProdList
4423
Advantage
58

890152-41-7, BocNH-PEG5-acidRelated Search:


  • BocNH-PEG5-acid
  • 5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(1,1-dimethylethyl) ester
  • t-boc-N-amido-PEG5-acetic acid
  • BocNH-P5-CH2CO2H
  • T-boc-n-amido-peg5-ch2co2h
  • NHBoc-PEG5-CH2COOH
  • BocNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(1,1-dimethylethyl) ester
  • 17-(Boc-amino)-3,6,9,12,15-pentaoxaheptadecan-1-oic Acid
  • 2-[2-[2-[2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
  • 17-{[(tert-butoxy)carbonyl]amino}-3,6,9,12,15-pentaoxaheptadecanoic acid
  • 2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid
  • 890152-41-7
  • C17H33NO9
  • peg