ChemicalBook > CAS DataBase List > PSMA-11

PSMA-11

Product Name: PSMA-11
CAS No.: 1366302-52-4
Chemical Name: PSMA-11
Synonyms: PSMA11;DKFZ-PSMA-11;PSMA-HBED-CC;PSMA-11 trifluoroacetate;HBED-CC-PSMA(1366302-52-4);1366302-52-4/2412149-32-5(TFA);HBED-CC-PSMA|||Psma-hbed-CC|||PSMA11;4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxypheny;4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxyphenyl]methyl](carboxymethyl)amin;(3S,7S)-22-(3-(((2-((5-(2-carboxyethyl)-2-hydroxybenzyl)(carboxymethyl)amino)ethyl)(carboxymethyl)amino)methyl)-4-hydroxyphenyl)-5,13,20-trioxo-4,6,12,19-tetraazadocosane-1,3,7-tricarboxylic acid
CBNumber: CB03376005
Molecular Formula: C44H62N6O17
Formula Weight: 946.99308
MOL File: 1366302-52-4.mol

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PSMA-11 Property

storage temp.: -20°C, protect from light
solubility: To be determined:100.0(Max Conc. mg/mL);105.6(Max Conc. mM)
form: Solid
color: White to off-white
InChIKey: QJUIUFGOTBRHKP-DPMCXAKDNA-N
SMILES: C(C(O)=O)C[C@@H](C(O)=O)NC(=O)N[C@H](C(O)=O)CCCCNC(=O)CCCCCNC(=O)CCC1=CC=C(O)C(CN(CCN(CC2=CC(CCC(O)=O)=CC=C2O)CC(O)=O)CC(O)=O)=C1 |&1:5,13,r|

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Hazard and Precautionary Statements (GHS)

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PSMA-11 Chemical Properties,Usage,Production

Description

PSMA-11 is a small molecule ligand that targets prostate-specific membrane antigen (PSMA) and has the ability to inhibit PSMA activity. PSMA-11 can be used to synthesize 68Ga-PSMA-11, a positron emission tomography (PET) tracer that can be used to image advanced prostate cancer.

Uses

The prostate-specific membrane antigen (PSMA) has received increased consideration during the past few years as an excellent target for both imaging and therapy of prostate cancer. ?After many years of outstanding preclin.

References

[1] Demirci E, et al. Normal distribution pattern and physiological variants of 68Ga-PSMA-11 PET/CT imaging. Nucl Med Commun. 2016 Nov;37(11):1169-79.
[2] Eder M, et al. 68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging[J]. Bioconjugate chemistry, 2012, 23(4): 688-697.
[3] Bois F, et al. [68Ga] Ga-PSMA-11 in prostate cancer: a comprehensive review[J]. American Journal of Nuclear Medicine and Molecular Imaging, 2020, 10(6): 349.
[4] ANDREI GAFITA. qPSMA: Semiautomatic Software for Whole-Body Tumor Burden Assessment in Prostate Cancer Using 68Ga-PSMA11 PET/CT.[J]. Journal of Nuclear Medicine, 2019, 60 9: 1277-1283. DOI:10.2967/jnumed.118.224055.

PSMA-11 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PSMA-11 manufacturers

Dingwang Technology (Wuhan) Co., Ltd.

Product: PSMA 11 1366302-52-4
Price: US $0.00/GRAM
Min. Order: 1GRAM
Purity: 99%
Supply Ability: 20 TONS
Release date: 2022-11-04

1366302-52-4, PSMA-11Related Search:

2-(4-((9S,13S)-9,13-Bis(Tert-Butoxycarbonyl)-18,18-Dimethyl-3,11,16-Trioxo-17-Oxa-2,4,10,12-Tetraazanonadecyl)Phenyl)Acetic Acid (S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid tert-Butyl-DCL (PSMA inhibitor) Vipivotide tetraxetan Linker L-Glutamic acid, N-[[[(1S)-1-carboxy-5-[[(6-fluoro-3-pyridinyl)carbonyl]amino]pentyl]amino]carbonyl]-

4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxyphenyl]methyl](carboxymethyl)amino]ethyl](carboxymethyl)amino]methyl]-4-hydroxyphenyl]-5,13,20-trioxo-, (3S,7S)-

PSMA11

4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxypheny

PSMA-11 trifluoroacetate

PSMA-HBED-CC

DKFZ-PSMA-11

HBED-CC-PSMA(1366302-52-4)

(3S,7S)-22-(3-(((2-((5-(2-carboxyethyl)-2-hydroxybenzyl)(carboxymethyl)amino)ethyl)(carboxymethyl)amino)methyl)-4-hydroxyphenyl)-5,13,20-trioxo-4,6,12,19-tetraazadocosane-1,3,7-tricarboxylic acid

1366302-52-4/2412149-32-5(TFA)

HBED-CC-PSMA|||Psma-hbed-CC|||PSMA11

4,6,12,19-Tetraazadocosane-1,3,7-tricarboxylic acid, 22-[3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxyphenyl]methyl](carboxymethyl)amin

1366302-52-4

C44H62N6O17