ChemicalBook > CAS DataBase List > DICHLORISONE ACETATE
DICHLORISONE ACETATE
- Product Name
- DICHLORISONE ACETATE
- CAS No.
- 79-61-8
- Chemical Name
- DICHLORISONE ACETATE
- Synonyms
- Sch 5005;DICHLORISONE ACETATE;dichlorisone 21-acetate;21-Acetyloxy-9,11β-dichloro-17-hydroxypregna-1,4-diene-3,20-dione;1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE;9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate;1,4-PREGNADIEN-9-ALPHA, 11-BETA-DICHLORO-17,21-DIOL-3,20-DIONE 21-ACETATE;inhibit,Inhibitor,Dichlorisone,Endogenous Metabolite,Dichlorisone Acetate;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11b)-;Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11β)-
- CBNumber
- CB0339584
- Molecular Formula
- C23H28Cl2O5
- Formula Weight
- 455.37
- MOL File
- 79-61-8.mol
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DICHLORISONE ACETATE Property
- Melting point:
- 246-253 °C (decomp)
- Boiling point:
- 596.2±50.0 °C(Predicted)
- alpha
- D25 +162° (dioxane)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 4.35 mg/mL (9.55 mM); Water: < 0.1 mg/mL (insoluble)
- pka
- 11.94±0.70(Predicted)
- form
- Solid
- color
- White to off-white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-7866
- Product name
- Dichlorisone acetate
- Purity
- 99.77%
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7866
- Product name
- Dichlorisone acetate
- Purity
- 99.77%
- Packaging
- 50mg
- Price
- $108
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- SHG0000402
- Product name
- DICHLORISONE ACETATE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $597.4
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- SHG0000402
- Product name
- DICHLORISONE ACETATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $695.39
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- SHG0000402
- Product name
- DICHLORISONE ACETATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1050.24
- Updated
- 2021/12/16
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DICHLORISONE ACETATE Chemical Properties,Usage,Production
Originator
Diloderm ,Schering,US,1960
Uses
antipruretic
Definition
ChEBI: Dichlorisone is a corticosteroid hormone.
Manufacturing Process
A solution of 1.0 g of 1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione-21-
acetate and 5.0 g of lithium chloride in 40 ml of glacial acetic acid is treated
with 0.410 g of N-chlorosuccinimide, followed by 0.104 g of anhydrous
hydrogen chloride dissolved in 2.5 ml of tetrahydrofuran. The reaction mixture
is stirred for 2 hours and poured into ice water. The crude product is filtered
and washed with water to give 1.12 g of solid material, which is recrystallized
from acetone-hexane to give substantially pure 9α,11β-dichloro-1,4-
pregnadiene-17α,21-diol-3,20-dione-21-acetate; MP 246°C to 253°C (dec.).
brand name
Diloderm (Schering).
Therapeutic Function
Antipruritic, Antihistaminic, Appetite stimulant
DICHLORISONE ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
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DICHLORISONE ACETATE Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
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