2-Chloro-N-methylacetamide
- Product Name
- 2-Chloro-N-methylacetamide
- CAS No.
- 96-30-0
- Chemical Name
- 2-Chloro-N-methylacetamide
- Synonyms
- N-Methylchloroacetamide;chloroacetylmethylamide;N-METHYL-2-CHLOROACETAMIDE;usafdo-35;USAF do-35;WLN: G1VM1;OTAVA-BB BB7020410071;2-chloro-n-methyl-acetamid;2-CHLORO-N-METHYLACETAMIDE;2-chloro-N-methyl-ethanamide
- CBNumber
- CB0341389
- Molecular Formula
- C3H6ClNO
- Formula Weight
- 107.54
- MOL File
- 96-30-0.mol
2-Chloro-N-methylacetamide Property
- Melting point:
- 38-40°C
- Boiling point:
- 112-115°C 20mm
- Density
- 1.127±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.38±0.46(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C3H6ClNO/c1-5-3(6)2-4/h2H2,1H3,(H,5,6)
- InChIKey
- HOZLOOPIXHWKCI-UHFFFAOYSA-N
- SMILES
- C(NC)(=O)CCl
- CAS DataBase Reference
- 96-30-0(CAS DataBase Reference)
- NIST Chemistry Reference
- ClCON(CH3)2(96-30-0)
Safety
- Risk Statements
- 36/37/38-43-22
- Safety Statements
- 26-36/37/39-36/37-24
- RTECS
- AB5775000
- HazardClass
- IRRITANT
- HS Code
- 29241990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OTV000964
- Product name
- 2-Chloro-N-methylacetamide
- Packaging
- 1g
- Price
- $70.9
- Updated
- 2024/03/01
- Product number
- C3014
- Product name
- 2-Chloro-N-methylacetamide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $61
- Updated
- 2024/03/01
- Product number
- C3014
- Product name
- 2-Chloro-N-methylacetamide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $203
- Updated
- 2024/03/01
- Product number
- H32362
- Product name
- 2-Chloro-N-methylacetamide, 97%
- Packaging
- 5g
- Price
- $71.65
- Updated
- 2024/03/01
- Product number
- H32362
- Product name
- 2-Chloro-N-methylacetamide, 97%
- Packaging
- 25g
- Price
- $270
- Updated
- 2024/03/01
2-Chloro-N-methylacetamide Chemical Properties,Usage,Production
Uses
2-Chloro-N-methylacetamide is an intermediate used to prepare piperidinylamino pyrrolopyrimidines as selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection.
Synthesis
To methylamine hydrochloride (896 mg, 13.3 mmol) and Na2C03 (5630 mg, 53 mmol) in water (26 mL) was added 2-chloroacetyl chloride (1500 mg, 13.3 mmol). The mixture was stirred at r.t. for lh and extracted with EtOAc (2x). The combined organic layers were dried over Na2S04 and concentrated to provide 2-Chloro-N-methylacetamide (1200 mg, 84%).
2-Chloro-N-methylacetamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-N-methylacetamide manufacturers
- Product
- 2-Chloro-N-methylacetamide 96-30-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-26
- Product
- 2-Chloro-N-methylacetamide 96-30-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-Chloro-N-methylacetamide 96-30-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25