ChemicalBook > CAS DataBase List > 2-Chloro-N-methylacetamide

2-Chloro-N-methylacetamide

Product Name
2-Chloro-N-methylacetamide
CAS No.
96-30-0
Chemical Name
2-Chloro-N-methylacetamide
Synonyms
N-Methylchloroacetamide;chloroacetylmethylamide;N-METHYL-2-CHLOROACETAMIDE;usafdo-35;USAF do-35;WLN: G1VM1;OTAVA-BB BB7020410071;2-chloro-n-methyl-acetamid;2-CHLORO-N-METHYLACETAMIDE;2-chloro-N-methyl-ethanamide
CBNumber
CB0341389
Molecular Formula
C3H6ClNO
Formula Weight
107.54
MOL File
96-30-0.mol
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2-Chloro-N-methylacetamide Property

Melting point:
38-40°C
Boiling point:
112-115°C 20mm
Density 
1.127±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
14.38±0.46(Predicted)
color 
White to Off-White
InChI
InChI=1S/C3H6ClNO/c1-5-3(6)2-4/h2H2,1H3,(H,5,6)
InChIKey
HOZLOOPIXHWKCI-UHFFFAOYSA-N
SMILES
C(NC)(=O)CCl
CAS DataBase Reference
96-30-0(CAS DataBase Reference)
NIST Chemistry Reference
ClCON(CH3)2(96-30-0)
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Safety

Risk Statements 
36/37/38-43-22
Safety Statements 
26-36/37/39-36/37-24
RTECS 
AB5775000
HazardClass 
IRRITANT
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
OTV000964
Product name
2-Chloro-N-methylacetamide
Packaging
1g
Price
$70.9
Updated
2024/03/01
TCI Chemical
Product number
C3014
Product name
2-Chloro-N-methylacetamide
Purity
>98.0%(GC)
Packaging
5g
Price
$61
Updated
2024/03/01
TCI Chemical
Product number
C3014
Product name
2-Chloro-N-methylacetamide
Purity
>98.0%(GC)
Packaging
25g
Price
$203
Updated
2024/03/01
Alfa Aesar
Product number
H32362
Product name
2-Chloro-N-methylacetamide, 97%
Packaging
5g
Price
$71.65
Updated
2024/03/01
Alfa Aesar
Product number
H32362
Product name
2-Chloro-N-methylacetamide, 97%
Packaging
25g
Price
$270
Updated
2024/03/01
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2-Chloro-N-methylacetamide Chemical Properties,Usage,Production

Uses

2-Chloro-N-methylacetamide is an intermediate used to prepare piperidinylamino pyrrolopyrimidines as selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection.

Synthesis

To methylamine hydrochloride (896 mg, 13.3 mmol) and Na2C03 (5630 mg, 53 mmol) in water (26 mL) was added 2-chloroacetyl chloride (1500 mg, 13.3 mmol). The mixture was stirred at r.t. for lh and extracted with EtOAc (2x). The combined organic layers were dried over Na2S04 and concentrated to provide 2-Chloro-N-methylacetamide (1200 mg, 84%).

2-Chloro-N-methylacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-N-methylacetamide Suppliers

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View Lastest Price from 2-Chloro-N-methylacetamide manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Chloro-N-methylacetamide 96-30-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chloro-N-methylacetamide 96-30-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
2-Chloro-N-methylacetamide 96-30-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-25

96-30-0, 2-Chloro-N-methylacetamideRelated Search:


  • OTAVA-BB BB7020410071
  • N-METHYL-2-CHLOROACETAMIDE
  • chloroacetylmethylamide
  • 2-CHLORO-N-METHYLACETAMIDE
  • 2-chloro-n-methyl-acetamid
  • Acetamide, 2-chloro-N-methyl-
  • alpha-Chloro-N-methylacetamide
  • N-Methylchloroacetamide
  • USAF do-35
  • usafdo-35
  • 2-chloro-N-methyl-ethanamide
  • 2-chloro-N-methylacetamide(SALTDATA: FREE)
  • 2-Chloro-<i>N</i>-methylacetamide
  • WLN: G1VM1
  • 2-Chloro-N-methylacetamide &gt
  • 2-Chloro-N-methylacetamide,97%
  • 2-Chloro-N-methylacetamide ISO 9001:2015 REACH
  • 96-30-0
  • Acids and Derivatives