ChemicalBook > CAS DataBase List > 7-(TRIFLUOROMETHYL)QUINOLINE

7-(TRIFLUOROMETHYL)QUINOLINE

Product Name
7-(TRIFLUOROMETHYL)QUINOLINE
CAS No.
325-14-4
Chemical Name
7-(TRIFLUOROMETHYL)QUINOLINE
Synonyms
7-Trrfluoromethylquinoline;7-(TRIFLUOROMETHYL)QUINOLINE;Quinoline, 7-(trifluoromethyl)-;7-(Trifluoromethyl)quinoline,97%
CBNumber
CB0347770
Molecular Formula
C10H6F3N
Formula Weight
197.16
MOL File
325-14-4.mol
More
Less

7-(TRIFLUOROMETHYL)QUINOLINE Property

Melting point:
65-67°C
Boiling point:
236.6℃ (762 Torr)
Density 
1.311±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
2.55±0.14(Predicted)
Appearance
White to off-white Solid
CAS DataBase Reference
325-14-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933499090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TRC
Product number
T895680
Product name
7-(Trifluoromethyl)quinoline
Packaging
100mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
PC520509
Product name
7-(Trifluoromethyl)quinoline
Purity
97%
Packaging
1g
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
023763
Product name
7-(Trifluoromethyl)quinoline
Purity
97%
Packaging
1g
Price
$123
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-3-0W
Product name
7-(Trifluoromethyl)quinoline
Purity
97%
Packaging
1g
Price
$128
Updated
2021/12/16
AK Scientific
Product number
N530
Product name
7-(Trifluoromethyl)quinoline
Packaging
1g
Price
$215
Updated
2021/12/16
More
Less

7-(TRIFLUOROMETHYL)QUINOLINE Chemical Properties,Usage,Production

Chemical Properties

yellow powder

Synthesis

98-16-8

56-81-5

325-14-4

1. Concentrated sulfuric acid (13.7 g, 0.14 mol) was slowly added dropwise to glycerol (8.63 g, 0.094 mol) at a controlled temperature not exceeding 70 °C. 2. m-Trifluoromethylaniline (5.00 g, 0.031 mol) was added to the above mixture, and the reaction was heated up to 85 °C, and kept at 85 °C for 40 min. 3. Potassium iodide (0.30 g, 1.80 mmol), iodine (0.34 g, 1.34 mmol), and water (1.50 mL) were added in sequence, and the reaction system was heated up to 135 °C for 4 hours. 4. 1.80 mmol), iodine (0.34 g, 1.34 mmol) and water (1.50 mL) were added sequentially, and the reaction system was heated to 135 °C and the reaction was sustained for 4 h. 4. Upon completion of the reaction, it was cooled to room temperature, and the reaction mixture was quenched by pouring it into iced water and filtered through diatomaceous earth. 5. The filtrate was adjusted to a pH of 7 with ammonia, pumped, and the filtrate was extracted with ethyl acetate. 6. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure.7. The residue was purified by column chromatography to afford 7-trifluoromethylquinoline (3.50 g, 69% yield).

References

[1] Patent: CN108409649, 2018, A. Location in patent: Paragraph 0042; 0043; 0044
[2] Patent: US2010/234340, 2010, A1. Location in patent: Page/Page column 21

7-(TRIFLUOROMETHYL)QUINOLINE Preparation Products And Raw materials

Raw materials

Oxalic acid 3-Nitrobenzotrifluoride Ethanol Glycerol Sodium iodide 3-Aminobenzotrifluoride Sulfuric acid

Preparation Products

More
Less

7-(TRIFLUOROMETHYL)QUINOLINE Suppliers

China 60 Europe 2 Germany 1 India 3 Ukraine 1 United Kingdom 3 United States 13 Global 83
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
More
Less

View Lastest Price from 7-(TRIFLUOROMETHYL)QUINOLINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
7-(TRIFLUOROMETHYL)QUINOLINE 325-14-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
7-(TRIFLUOROMETHYL)QUINOLINE 325-14-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-02-04

325-14-4, 7-(TRIFLUOROMETHYL)QUINOLINERelated Search:

7-(TRIFLUOROMETHYL)QUINOLIN-2-AMINE 7-(TrifluoroMethyl)quinoline-3-carboxylic acid ethyl ester 4-Chloro-7-(trifluoromethyl)quinoline 98%,4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE, 9 8% 7-(Trifluoromethyl)quinoline-4-thiol, tech.,7-(trifluoromethyl)quinoline-4-thiol 4-Hydroxy-7-(trifluoromethyl)quinoline 98% 6,8-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE 4-BROMO-7-CHLORO-8-METHYL-2-(TRIFLUOROMETHYL)QUINOLINE 4-HYDROXY-8-METHYL-2-(TRIFLUOROMETHYL)QUINOLINE 2,8-BIS(TRIFLUOROMETHYL)-4-BROMOQUINOLINE 2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE 4,7-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 6-CHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid 85% 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE, 9 7%,4-Chloro-8-(trifluoromethyl)quinoline 98% 4-Chloro-2-(trifluoromethyl)quinoline 97% 7-CHLORO-8-METHYL-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL 8-(TRIFLUOROMETHOXY)-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL

  • 7-(TRIFLUOROMETHYL)QUINOLINE
  • 7-Trrfluoromethylquinoline
  • Quinoline, 7-(trifluoromethyl)-
  • 7-(Trifluoromethyl)quinoline,97%
  • 325-14-4
  • 325-14-1
  • C10H6F3N
  • Quinoline&Isoquinoline
  • Miscellaneous