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Tetramethylammonium acetate

Product Name
Tetramethylammonium acetate
CAS No.
10581-12-1
Chemical Name
Tetramethylammonium acetate
Synonyms
[M4N]Ac;tetraMethylazaniuM;Tetramethylazanium acetate;TetraMethylaMMoniuM acetat;TETRAMETHYLAMMONIUM ACETATE;n,n,n-trimethyl-methanaminiuacetate;TETRAMETHYLAMMONIUM ACETATE HYDRATE;TETRAMETHYLAMMONIUM ACETATE, 90% TECH.;METHANAMINIUM,N,N,N-TRIMETHYL-,ACETATE;Tetramethylammonium acetate, tech. 90%
CBNumber
CB0348065
Molecular Formula
C6H15NO2
Formula Weight
133.19
MOL File
10581-12-1.mol
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Tetramethylammonium acetate Property

Melting point:
184 °C (dec.) (lit.)
Density 
1.000g/cm3 at 20°C
storage temp. 
Store below +30°C.
form 
Crystalline Solid
color 
White
Water Solubility 
Soluble in water.
Sensitive 
Hygroscopic
BRN 
3571830
InChI
InChI=1S/C4H12N.C2H4O2/c1-5(2,3)4;1-2(3)4/h1-4H3;1H3,(H,3,4)/q+1;/p-1
InChIKey
MRYQZMHVZZSQRT-UHFFFAOYSA-M
SMILES
[N+](C)(C)(C)C.C(=O)([O-])C
CAS DataBase Reference
10581-12-1(CAS DataBase Reference)
EPA Substance Registry System
Methanaminium, N,N,N-trimethyl-, acetate (10581-12-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
F 
3-10
TSCA 
Yes
HS Code 
29239000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
245070
Product name
Tetramethylammonium acetate
Purity
≥97%
Packaging
5g
Price
$24.66
Updated
2025/07/31
Sigma-Aldrich
Product number
245070
Product name
Tetramethylammonium acetate
Purity
≥97%
Packaging
25g
Price
$128
Updated
2025/07/31
TCI Chemical
Product number
T1048
Product name
Tetramethylammonium Acetate
Purity
>98.0%(T)
Packaging
5g
Price
$46
Updated
2025/07/31
TCI Chemical
Product number
T1048
Product name
Tetramethylammonium Acetate
Purity
>98.0%(T)
Packaging
25g
Price
$153
Updated
2025/07/31
TCI Chemical
Product number
T1397
Product name
Tetramethylammonium Acetate (ca. 15% in Water)
Packaging
25g
Price
$86
Updated
2025/07/31
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Tetramethylammonium acetate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to pale yellow solution

Uses

Tetramethylammonium acetate is used as an intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. Further, it is used to prepare (1R,4S)-4-hydroxycyclopent-2-en-1-essigsaeure-methylester by reacting with 1,3-dimethyl-imidazolidin-2-one. In addition to this, it serves as an emulsifier, catalyst, sterilizer, antistatic and antiseptic agent.

Synthesis

75-59-2

64-19-7

10581-12-1

General procedure for the synthesis of tetramethylammonium acetate from tetramethylammonium hydroxide and glacial acetic acid: 247 mg (4.11 mmol) of glacial acetic acid and 1.50 g (4.11 mmol) of tetramethylammonium hydroxide (25% wt. of methanol solution) were dissolved in 10 mL of methanol. The reaction mixture was stirred at 40°C for 4 hours. Upon completion of the reaction, the reaction solution was filtered and the solvent was subsequently removed using a rotary evaporator to give a viscous oil which gradually solidified. The residual trace solvent was removed under high vacuum to give a white solid product. The white solid was washed with ether and subsequently dried under vacuum to give 480 mg of white solid tetramethylammonium acetate in 87.6% yield.

References

[1] Patent: US2010/105770, 2010, A1. Location in patent: Page/Page column 12

Tetramethylammonium acetate Preparation Products And Raw materials

Raw materials

Preparation Products

4-CHLORO-N-METHYLPYRIMIDIN-2-AMINE N-(4-AMINOPYRIMIDIN-2-YL)-N-METHYLAMINE
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Tetramethylammonium acetate Suppliers

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View Lastest Price from Tetramethylammonium acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tetramethylammonium acetate 10581-12-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-23
Hebei Fengjia New Material Co., Ltd
Product
Tetramethylammonium acetate 10581-12-1
Price
US $4.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100000
Release date
2024-09-12
HebeiShuoshengImportandExportco.,Ltd
Product
Tetramethylammonium acetate 10581-12-1
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08

10581-12-1, Tetramethylammonium acetateRelated Search:

Ethyl acetate Glatiramer acetate Ammonium acetate Potassium Acetate Octamethylcyclotetrasiloxane Butyl acetate Tocopheryl acetate Methyl acetate Tetrabutylammonium acetate Tetramethylammonium hydroxide N,N,N',N'-Tetramethylethylenediamine Sodium acetate Vinyl acetate Tetramethylammonium fluoride Tetramethylammonium fluoride tetrahydrate TETRAMETHYLAMMONIUM TRIACETOXYBOROHYDRIDE Tetramethylammonium iodide TETRAMETHYLAMMONIUM DICHLOROIODATE(I)

  • TETRAMETHYLAMMONIUM ACETATE
  • TETRAMETHYLAMMONIUM ACETATE HYDRATE
  • n,n,n-trimethyl-methanaminiuacetate
  • TETRAMETHYLAMMONIUM ACETATE, 90% TECH.
  • Tetramethylammonium acetate, 50% aqueous solution
  • METHANAMINIUM,N,N,N-TRIMETHYL-,ACETATE
  • Tetramethylammonium Acetate (ca. 15% in Water)
  • Tetramethylammonium acetate, tech. 90%
  • TetraMethylaMMoniuM acetate Monohydrate
  • Tetramethylazanium acetate
  • tetraMethylazaniuM
  • TetraMethylaMMoniuM acetate, 50% aqueous solution 5GR
  • TetraMethylaMMoniuM acetat
  • Tetramethylammonium acetate technical grade, 90%
  • [M4N]Ac
  • TetraMethylaMMoniuM Acetate , 98.0%(T)
  • Methanaminium, N,N,N-trimethyl-, acetate (1:1)
  • Tetramethylammonium acetate ISO 9001：2015 REACH
  • CAS10581-12-1 Tetramethylammonium acetate
  • 10581-12-1
  • C4H12NC2H3O2
  • C6H15NO2xH2O
  • CH34NOCOCH3
  • CH34NOOCCH3
  • CH34NOAc
  • CH34NOCOCH3xH2O
  • C2H3O2C4H12N
  • C4H12NC2H3O2H2O
  • Phase Transfer Catalysts
  • Synthetic Reagents
  • Ammonium Salts
  • Ammonium Polyhalides, etc. (Quaternary)
  • Quaternary Ammonium Compounds
  • quarternary ammonium salts
  • Ammonium Polyhalides, etc. (Quaternary)
  • Quaternary Ammonium Compounds
  • Ammonium Salts
  • Greener Alternatives: Catalysis
  • Phase Transfer Catalysts
  • bc0001