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4-Pyridylmercapto acetyl chloride hydrochloride

Product Name
4-Pyridylmercapto acetyl chloride hydrochloride
CAS No.
27230-51-9
Chemical Name
4-Pyridylmercapto acetyl chloride hydrochloride
Synonyms
2-(Pyridin-4-ylthio);Phenol,3-fluoro-9-iodo-;7-Side chain of Cefapirin;acetyl chloride hydrochloride;4-pyridylMercapto acetyl chloride;4-PYRIDYLMERCAPTOACETYL CHLORIDE HCL;(4-Pyridylthio)acetyl choride hydrochloride;(4-pyridylthio)acetyl chloride hydrochloride;4-PYRIDYLMERCAPTOACETYL CHLORIDE HYDROCHLORIDE;2-(4-Pyridylthio)acetyl Chloride Hydrochloride
CBNumber
CB0349279
Molecular Formula
C7H7Cl2NOS
Formula Weight
224.1
MOL File
27230-51-9.mol
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4-Pyridylmercapto acetyl chloride hydrochloride Property

InChI
InChI=1S/C7H6ClNOS.ClH/c8-7(10)5-11-6-1-3-9-4-2-6;/h1-4H,5H2;1H
InChIKey
ONINFWNBKWMUCA-UHFFFAOYSA-N
SMILES
S(C1=CC=NC=C1)CC(=O)Cl.Cl
CAS DataBase Reference
27230-51-9(CAS DataBase Reference)
EPA Substance Registry System
Acetyl chloride, (4-pyridinylthio)-, hydrochloride (27230-51-9)
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Safety

TSCA 
TSCA listed
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P992060
Product name
4-Pyridylmercaptoacetylchloridehydrochloride
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
P991895
Product name
4-PyridylmercaptoacetylChloride
Packaging
5g
Price
$495
Updated
2021/12/16
AK Scientific
Product number
E582
Product name
4-PyridylmercaptoacetylchlorideHCl
Packaging
1g
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0129432
Product name
4-PYRIDYLMERCAPTO ACETYL CHLORIDE HYDROCHLORIDE
Purity
95.00%
Packaging
5G
Price
$349.65
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
48474
Product name
4-PyridylmercaptoacetylChloride
Packaging
250mg
Price
$575
Updated
2021/12/16
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4-Pyridylmercapto acetyl chloride hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White crystalline solid

Uses

4-Pyridylmercaptoacetyl Chloride is a reagent used in the synthesis of Cephalosporin (C258750) derivatives, used as an antibiotic.

Synthesis

4-Pyridylmercaptoacetic acid: 600-m1 of sodium hydroxide (88, 4, 9, 2, 21 mol) and water were placed in an EndPage:3 flask equipped with a condenser. 80-Mercaptoacetic acid (76, 79, 0, 67 mol) was added with stirring, followed by 4-chloropyridine hydrochloride (100 g, 0.67 mol). The mixture was heated under stirring at reflux temperature for 4 hours. About 5 g of cooled decolorized carbon was added to the resulting solution at 80??C. Stirring was continued for 5 min and then filtered using a filter aid. The r solution was acidified to pH 4.5 by the addition of acetic acid. the resulting slurry was cooled to 5 ??C and filtered to collect. 100 ml of solid! Wash Dissolve the wet filter cake in 6 NHC, 200 m,g and 500 ml of water. The clear solution was about 200 ml of 10% sodium hydroxide! Neutralize to pH 5. The slurry is cooled to 5??C, collected on a filter and washed with 200 ml of water. The solid was then washed with isopropanol 100rrLe. The product, 4-pyridylmercaptoacetic acid, was dried at 50 ??C at room temperature to give about 829 (73). Melting point 267-268??C (decomposition). Literature value: mp270°C.

4-Pyridylmercapto acetyl chloride hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Pyridylmercapto acetyl chloride hydrochloride Suppliers

Cato Research Chemicals Inc.
Tel
020-81960175-877 18933936954
Email
tianwen.zhan@cato-chem.com
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China
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7318
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58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
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0311-89250318 031166536426
Fax
4000311741
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master@sjzsdyn.com
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China
ProdList
2768
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XiaoGan ShenYuan ChemPharm co,ltd
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15527621225
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1791901229@qq.com
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China
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Nanjing Vital Chemical Co., Ltd.
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Please Send Email 18652950785
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025-87193546
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chemweiao@163.com
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China
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Shanghai Meishui Chemical Technology Co., Ltd
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021-60549325 18616193163
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021-33250306
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China
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Hangzhou J&H Chemical Co., Ltd.
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0571-87396432
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0571-87396431
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sales@jhechem.com
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China
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Nanjing Duolong Bio-tech Co.,Ltd.
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18905173768
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025-83263139
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52513593@qq.com
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China
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Quzhou Rundong Chemical (Technology) Co.
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0570-8789886 18892685668
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0570-8789985
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China
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Kaifute(Tianjin)Chemical Co., Ltd.
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022-58659859 13820733852
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022-5865 9859
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sales@kftchem.com
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China
ProdList
299
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55
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
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View Lastest Price from 4-Pyridylmercapto acetyl chloride hydrochloride manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
4-Pyridylmercapto acetyl chloride hydrochloride 27230-51-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-04-15
Hebei Yanxi Chemical Co., Ltd.
Product
4-Pyridylmercapto acetyl chloride hydrochloride 27230-51-9
Price
US $0.00/kg
Min. Order
1kg
Purity
95.00%
Supply Ability
20tons
Release date
2023-09-12
HEBEI BRANT PHARMACEUTICAL CO.,LTD
Product
(4-Pyridylthio)acetyl choride hydrochloride 27230-51-9
Price
US $0.00-0.00/kg
Min. Order
100kg
Purity
≥94.0%
Supply Ability
20 tons
Release date
2024-07-31

27230-51-9, 4-Pyridylmercapto acetyl chloride hydrochlorideRelated Search:


  • 4-PYRIDYLMERCAPTOACETYL CHLORIDE HYDROCHLORIDE
  • (4-pyridylthio)acetyl chloride hydrochloride
  • 4-PYRIDYLMERCAPTOACETYL CHLORIDE HCL
  • 4-pyridylMercapto acetyl chloride
  • 4-PyridylMercapto acetyl chloride hydrochloride,PMAC
  • 2-(pyridin-4-ylthio)acetyl chloride hydrochloride
  • 2-(Pyridin-4-ylthio)
  • acetyl chloride hydrochloride
  • 2-(4-Pyridylthio)acetyl Chloride Hydrochloride
  • Acetyl chloride, (4-pyridinylthio)-, hydrochloride
  • Phenol,3-fluoro-9-iodo-
  • 7-Side chain of Cefapirin
  • (4-Pyridylthio)acetyl choride hydrochloride
  • 27230-51-9
  • 27230-51-8
  • C7H6ClNOSHCl
  • C7H6ClNOSHClC7H7Cl2NOS