(+)-MAGNOFLORINE IODIDE
- Product Name
- (+)-MAGNOFLORINE IODIDE
- CAS No.
- 2141-09-5
- Chemical Name
- (+)-MAGNOFLORINE IODIDE
- Synonyms
- escholin;Esholine;escholine;THALICTRIN;Aids002649;Magflorine;THALICTRINE;Aids-002649;MAGNOFLORINE;(+)-Magnoflorine
- CBNumber
- CB0350572
- Molecular Formula
- C20H24INO4
- Formula Weight
- 469.31
- MOL File
- 2141-09-5.mol
(+)-MAGNOFLORINE IODIDE Property
- Melting point:
- 252℃
- storage temp.
- 2-8°C(protect from light)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25122
- Product name
- Magnoflorine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 25122
- Product name
- Magnoflorine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $145
- Updated
- 2024/03/01
- Product number
- 25122
- Product name
- Magnoflorine
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $337
- Updated
- 2024/03/01
- Product number
- 25122
- Product name
- Magnoflorine
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $625
- Updated
- 2024/03/01
- Product number
- 300608
- Product name
- Magnoflorine Iodide
- Packaging
- 10mg
- Price
- $448
- Updated
- 2021/12/16
(+)-MAGNOFLORINE IODIDE Chemical Properties,Usage,Production
Description
A wide variety of species contain this quaternary alkaloid which is widespread among the families, Aquilegia, Magnolia and Michelia. It has been isolated and characterized as the iodide, m.p. 248-9°C (dec.); [0:11>5 + 200.1° (MeOH). The optically inactive base also yields an iodide which crystallizes with 1.5 H20, m.p. 243°C (dec.).
Description
Magnoflorine is an alkaloid and a major constituent of S. acutum that has diverse biological activities. It reduces hemolysis induced by lysophosphatidylcholine (LPC), but not NaCl, in a rat erythrocyte suspension when used at concentrations ranging from 0.01 to 10 μM. Magnoflorine (10 μM) induces intracellular chloride influx in neuroblastoma cells, an effect that is reversed by the GABAA receptor antagonist bicuculline . It reduces TNF-α-induced NF-κB expression as well as production of IL-6 and IL-8 in BEAS-2B cells. In vivo, magnoflorine (20 mg/kg, i.p.) improves short- and long-term memory acquisition in a passive avoidance test in a mouse model of scopolamine-induced memory impairment.
Uses
Magnoflorine-d3 is the labelled analogue of Magnoflorine, an isoquinoline alkaloid from the Coptis japonica and it enhances the myoblast differentiation through activation of the p38 MAP kinase and Akt pathway.
Definition
ChEBI: (S)-magnoflorine is an aporphine alkaloid that is (S)-corytuberine in which the nitrogen has been quaternised by an additional methyl group. It has a role as a plant metabolite. It is an aporphine alkaloid and a quaternary ammonium ion. It is functionally related to a (S)-corytuberine.
References
Nakano., Chem. Pharm. Bull. (Tokyo), 2, 329 (1954) Tomita, Kikkawa.,J. Pharm. Soc., Japan, 77, 195 (1957) Gopinath et aI., J. Sci. Ind. Res., 18B, 444 (1959) Ishii, Harada.,J. Pharm. Soc., Japan, 81,238 (1961) Yang, Lu, Hsiao., ibid, 82,794,816 (1962) Yang, Lu, Hsiao., ibid, 83,216 (1963)
(+)-MAGNOFLORINE IODIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-MAGNOFLORINE IODIDE Suppliers
- Tel
- --
- Fax
- --
- info@cas.cz
- Country
- Czech
- ProdList
- 364
- Advantage
- 91
View Lastest Price from (+)-MAGNOFLORINE IODIDE manufacturers
- Product
- magnoflorine 2141-09-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-24
- Product
- Magnoflorine 2141-09-5
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-09
- Product
- (+)-MAGNOFLORINE IODIDE 2141-09-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12