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epiberberine

Product Name
epiberberine
CAS No.
6873-09-2
Chemical Name
epiberberine
Synonyms
Siberian;BerbiniuM;epiberberine;Epiberberine Chloride;11,12-Dihydro-8,9-dimethoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium;8,9-Dimethoxy-11,12-dihydro-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinolin-13-ium
CBNumber
CB81385249
Molecular Formula
C20H18NO4+
Formula Weight
336.36122
MOL File
6873-09-2.mol
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epiberberine Property

Melting point:
260℃
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Orange to Dark Orange
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
300220
Product name
Epiberberine
Packaging
20mg
Price
$349
Updated
2021/12/16
ApexBio Technology
Product number
N2453
Product name
Epiberberine
Packaging
10mg
Price
$120
Updated
2021/12/16
ApexBio Technology
Product number
N2453
Product name
Epiberberine
Packaging
10mM(in 1mL DMSO)
Price
$180
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259213
Product name
Epiberberine
Purity
98%
Packaging
20mg
Price
$391
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0002408
Product name
EPIBERBERINE
Purity
95.00%
Packaging
5MG
Price
$505.48
Updated
2021/12/16
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epiberberine Chemical Properties,Usage,Production

Chemical Properties

Red needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Coptis chinensis.

Uses

Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.

in vivo

Epiberberine (225 mg/kg, p.o. daily for 40 days) reduces body weight, food consumption, water intake, and urinary output of KK-Ay mice[3].

target

MEK | ERK | AMPK | Akt | Fatty Acid Synthase | Raf | P450 (e.g. CYP17) | LDL | HMG-CoA Reductase | AChE | BACE | ROS

IC 50

AChE; BACE1; BChE

epiberberine Preparation Products And Raw materials

Raw materials

Preparation Products

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epiberberine Suppliers

Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4790
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
5000
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
8000
Advantage
58
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View Lastest Price from epiberberine manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Epiberberine 6873-09-2
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-06
Career Henan Chemical Co
Product
epiberberine 6873-09-2
Price
US $8.00/KG
Min. Order
1g
Purity
>98% HPLC
Supply Ability
kg--ton
Release date
2020-02-20

6873-09-2, epiberberineRelated Search:


  • epiberberine
  • BerbiniuM
  • 11,12-Dihydro-8,9-dimethoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium
  • Epiberberine Chloride
  • Siberian
  • 8,9-Dimethoxy-11,12-dihydro-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinolin-13-ium
  • 6873-09-2
  • 6873-9-2
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract