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Palmatine chloride

Product Name
Palmatine chloride
CAS No.
10605-02-4
Chemical Name
Palmatine chloride
Synonyms
PALMATINE HYDROCHLORIDE;Huangtengsu;Palmatine HCL;Palatinechloride;PALMATINE CHLORIDE;BERBERICINE CHLORIDE;Fibrauretin Chloride;Palmatine chloride-RM;PalMatin hydrochloride;Palmatine chloride, ≥98%
CBNumber
CB8467599
Molecular Formula
C21H22ClNO4
Formula Weight
387.86
MOL File
10605-02-4.mol
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Palmatine chloride Property

Melting point:
205℃
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Solid
color 
Yellow
InChI
InChI=1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1
InChIKey
RLQYRXCUPVKSAW-UHFFFAOYSA-M
SMILES
C12=CC3=C(C(OC)=C(OC)C=C3)C=[N+]1CCC1C=C(OC)C(OC)=CC2=1.[Cl-]
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Safety

Risk Statements 
20/22-36/38
Safety Statements 
24/45
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30318
Product name
Palmatine (chloride)
Packaging
500mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
30318
Product name
Palmatine (chloride)
Packaging
1g
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
30318
Product name
Palmatine (chloride)
Packaging
5g
Price
$220
Updated
2024/03/01
Usbiological
Product number
300750
Product name
Palmatine Chloride
Packaging
20mg
Price
$255
Updated
2021/12/16
TRC
Product number
P144200
Product name
PalmatineChloride
Packaging
10g
Price
$575
Updated
2021/12/16
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Palmatine chloride Chemical Properties,Usage,Production

Description

Corydalis paUida yields this alkaloid which occurs in the quaternary base fraction. The alkaloid is separated by droplet countercurrent chromatography and crystallizes from H20 as yellow-green needles.

Description

Palmatine is an alkaloid that has been found in C. rhizoma and has diverse biological activities. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 0.51 and 6.84 μM, respectively). Palmatine (20, 40, and 80 μM) reduces Zika virus infection of Vero cells in a concentration-dependent manner. In vivo, palmatine (50 and 100 mg/kg) reduces colonic myeloperoxidase (MPO) activity and IL-10, IL-1β, IL-6, and TNF-α levels, as well as protects mucosal integrity in a mouse model of colitis induced by dextran sulfate (DSS; ). It reduces stomach ulcer area in a rat model of acetic acid-induced gastric ulcers. Palmatine (10 and 20 mg/kg) reduces the number of small intestine and colon tumors in the ApcMin+/- mouse model of multiple intestinal neoplasia.

Uses

Palmatine Chloride is a protoberberine alkaloid, as a potential anti-inflammatory and anti-hypertensive agent.

Uses

antibacterial, antimalarial, uterine contractant

target

Antifection

References

Tani, Nakagura, Hattori, Yakugaku Zasshi, 95, 1103 (1975)

Palmatine chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Palmatine chloride Suppliers

Chengdu Chenlv Herb Co., Ltd.
Tel
028-88523492 15528171243
Email
chenrongpharma@126.com
Country
China
ProdList
124
Advantage
58
Shanghai Jiaoze Industrial Co., LTD
Tel
021-37318802 18616909727
Fax
021-37318802
Email
liangpanpan@sh-jiaoze.com
Country
China
ProdList
116
Advantage
58
Hubei DAHAO Chemical Co., Ltd.
Tel
027-59106191 13986034860
Email
1400828855@qq.com
Country
China
ProdList
8931
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
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View Lastest Price from Palmatine chloride manufacturers

Chengdu ChenLv Herb Co.,Ltd
Product
Palmatine hcl 10605-02-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
CP2020
Supply Ability
10tons
Release date
2023-08-04
Shanghai Standard Technology Co., Ltd.
Product
Palmatine hydrochloride 10605-02-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-24
Shanghai Standard Technology Co., Ltd.
Product
Palmatine hydrochloride 10605-02-4
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-10-24

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