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Palmatine chloride

Product Name
Palmatine chloride
CAS No.
10605-02-4
Chemical Name
Palmatine chloride
Synonyms
PALMATINE HYDROCHLORIDE;Huangtengsu;Palmatine HCL;Palatinechloride;PALMATINE CHLORIDE;BERBERICINE CHLORIDE;Fibrauretin Chloride;PalMatin hydrochloride;Palmatine chloride, ≥98%;Palmatine chloride USP/EP/BP
CBNumber
CB8467599
Molecular Formula
C21H22ClNO4
Formula Weight
387.86
MOL File
10605-02-4.mol
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Palmatine chloride Property

Melting point:
205℃
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Solid
color 
Yellow
InChI
InChI=1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1
InChIKey
RLQYRXCUPVKSAW-UHFFFAOYSA-M
SMILES
C12=CC3=C(C(OC)=C(OC)C=C3)C=[N+]1CCC1C=C(OC)C(OC)=CC2=1.[Cl-]
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Safety

Risk Statements 
20/22-36/38
Safety Statements 
24/45
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30318
Product name
Palmatine (chloride)
Packaging
500mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
30318
Product name
Palmatine (chloride)
Packaging
1g
Price
$85
Updated
2024/03/01
Cayman Chemical
Product number
30318
Product name
Palmatine (chloride)
Packaging
5g
Price
$220
Updated
2024/03/01
Usbiological
Product number
300750
Product name
Palmatine Chloride
Packaging
20mg
Price
$255
Updated
2021/12/16
TRC
Product number
P144200
Product name
PalmatineChloride
Packaging
10g
Price
$575
Updated
2021/12/16
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Palmatine chloride Chemical Properties,Usage,Production

Description

Corydalis paUida yields this alkaloid which occurs in the quaternary base fraction. The alkaloid is separated by droplet countercurrent chromatography and crystallizes from H20 as yellow-green needles.

Description

Palmatine is an alkaloid that has been found in C. rhizoma and has diverse biological activities. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 0.51 and 6.84 μM, respectively). Palmatine (20, 40, and 80 μM) reduces Zika virus infection of Vero cells in a concentration-dependent manner. In vivo, palmatine (50 and 100 mg/kg) reduces colonic myeloperoxidase (MPO) activity and IL-10, IL-1β, IL-6, and TNF-α levels, as well as protects mucosal integrity in a mouse model of colitis induced by dextran sulfate (DSS; ). It reduces stomach ulcer area in a rat model of acetic acid-induced gastric ulcers. Palmatine (10 and 20 mg/kg) reduces the number of small intestine and colon tumors in the ApcMin+/- mouse model of multiple intestinal neoplasia.

Uses

Palmatine Chloride is a protoberberine alkaloid, as a potential anti-inflammatory and anti-hypertensive agent.

Uses

antibacterial, antimalarial, uterine contractant

target

Antifection

References

Tani, Nakagura, Hattori, Yakugaku Zasshi, 95, 1103 (1975)

Palmatine chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Palmatine chloride Suppliers

China 194 Europe 2 France 1 Germany 2 India 2 Japan 2 United Kingdom 1 United States 24 Global 228
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View Lastest Price from Palmatine chloride manufacturers

Chengdu ChenLv Herb Co.,Ltd
Product
Palmatine hcl 10605-02-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
CP2020
Supply Ability
10tons
Release date
2023-08-04
Shanghai Standard Technology Co., Ltd.
Product
Palmatine hydrochloride 10605-02-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-24
Shanghai Standard Technology Co., Ltd.
Product
Palmatine hydrochloride 10605-02-4
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-10-24

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  • Palmatine chloride, ≥98%
  • 10605-02-4
  • C21H21NO4HCl
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors