(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE

Product Name: (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
CAS No.: 110859-47-7
Chemical Name: (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
Synonyms: BUTTPARK 85\12-11;Mosapride Impurity 22;2-Aminomethyl-4-benzylmorpholine;4-Benzyl-2-(aMinoMethyl)Morpholine;4-(Benzyl)-2-morpholinemethanamine;(4-BENZYLMORPHOLIN-2-YL)METHYLAMINE;(4-Benzyl-2-Morpholinyl)MethanaMine;(4-BENZYLMORPHOLIN-2-YL) METHANAMINE;1-(4-Benzylmorpholin-2-yl)methanamine;(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE
CBNumber: CB0351791
Molecular Formula: C12H18N2O
Formula Weight: 206.28
MOL File: 110859-47-7.mol

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(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Property

Boiling point:: 120-122°C 0,5mm
Density: 1.076
Flash point:: 143℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: 9.37±0.29(Predicted)
Appearance: Colorless to light yellow Viscous Liquid
optical activity: 0.15°(C=1 g/100ml MEOH)
CAS DataBase Reference: 110859-47-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 34
Safety Statements: 26-36/37/39
RIDADR: 2735
Hazard Note: Irritant
HS Code: 2921199990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B130525
Product name: (4-Benzylmorpholin-2-yl)methanamine
Packaging: 1g
Price: $275
Updated: 2021/12/16

AK Scientific

Product number: X8960
Product name: (4-Benzylmorpholin-2-yl)methanamine
Packaging: 250mg
Price: $117
Updated: 2021/12/16

Apolloscientific

Product number: OR23186
Product name: (4-Benzylmorpholin-2-yl)methylamine
Purity: 95+%
Packaging: 500mg
Price: $149
Updated: 2021/12/16

Matrix Scientific

Product number: 081960
Product name: (4-Benzyl-1,4-oxazinan-2-yl)methylamine
Purity: 97%
Packaging: 1g
Price: $342
Updated: 2021/12/16

AK Scientific

Product number: X8960
Product name: (4-Benzylmorpholin-2-yl)methanamine
Packaging: 5g
Price: $511
Updated: 2021/12/16

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(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Chemical Properties,Usage,Production

Synthesis

110859-48-8

110859-47-7

General procedure for the synthesis of (4-benzyl-2-morpholinyl)methanamine from 2-[[4-(benzyl)-2-morpholinyl]methyl]-1H-isoindole-1,3(2H)-dione: To a 50 mL single-necked round-bottomed flask was added 2-(4-benzylmorpholin-2-yl)methylphthalimide (1.3 g, 3.87 mmol) and hydrazine hydrate (0.38 g, 7.6 mmol) and ethanol (13 mL) was added. The mixture was heated to 80 °C and then stirred for 4 hours. After completion of the reaction, which was monitored by thin layer chromatography (TLC), the resulting solution was cooled to room temperature and filtered to separate the inorganic material. The filtrate was concentrated under vacuum, 10% sodium hydroxide solution (10 mL) was added and extracted twice with dichloromethane (20 mL). All extracted organic layers were combined, dried with anhydrous magnesium sulfate and filtered. The filtrate was concentrated under vacuum to give a solid product. The resulting solid was dried in an oven at 60 °C to give (4-benzylmorpholin-2-yl)methylamine (550 mg, 69% yield). The dried product was used directly in the subsequent reaction.

References

[1] Journal of Medicinal Chemistry, 1990, vol. 33, # 5, p. 1406 - 1413
[2] Journal of Medicinal Chemistry, 1993, vol. 36, # 10, p. 1356 - 1363
[3] Patent: WO2012/128582, 2012, A2. Location in patent: Page/Page column 110
[4] Patent: WO2007/71936, 2007, A1. Location in patent: Page/Page column 86

(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Suppliers

Belgium 1 Canada 1 China 97 Germany 3 India 1 Ukraine 2 United Kingdom 6 United States 20 Global 131

J & K SCIENTIFIC LTD.

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View Lastest Price from (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Mosapride Impurity 22
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-10

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Mosapride Impurity 22
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE 110859-47-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

110859-47-7, (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINERelated Search:

(4-BENZYL-1,4-OXAZINAN-2-YL)METHANOL 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine Mosapride citrate (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE Mosapride 4-BENZYL-2-((PYRROLIDIN-1-YL)METHYL) MORPHOLINE (4-BENZYL-MORPHOLIN-2-YLMETHYL)-DIMETHYL-AMINE (4-BENZYL-MORPHOLIN-2-YLMETHYL)-METHYL-AMINE 4-amino-N-((4-benzyl-2-morpholinyl)-methyl)-5-chloro-2-ethoxybenzamide BUTTPARK 121\16-92 (4-BENZYL-MORPHOLIN-2-YLMETHYL)-ETHYL-AMINE (4-BENZYL-MORPHOLIN-2-YLMETHYL)-DIETHYL-AMINE 4-BENZYL-2-((PIPERIDIN-1-YL)METHYL) MORPHOLINE (2-AMINOMETHYL-MORPHOLIN-4-YL)-PHENYL-METHANONE 4-amino-N-((4-benzyl-2-morpholinyl)methyl)-5-chloro-2-methoxybenzamide N-((4-benzyl-2-morpholinyl)methyl)-5-chloro-4-(dimethylamino)-2-methoxybenzamide BUTTPARK 121\16-91 N-(4-BENZYL-MORPHOLIN-2-YLMETHYL)-2-CHLORO-ACETAMIDE

BUTTPARK 85\12-11

C-(4-BENZYL-MORPHOLIN-2-YL)-METHYLAMINE

(4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE

N-methyl-1-(5-methyl-3-isoxazolyl)methanamine

4-Benzyl-2-(aMinoMethyl)Morpholine

[[4-(Phenylmethyl)-2-morpholinyl]methyl]amine

1-(4-Benzylmorpholin-2-yl)methanamine

(4-BENZYLMORPHOLIN-2-YL) METHANAMINE

(4-BENZYLMORPHOLIN-2-YL)METHYLAMINE

(4-Benzyl-1,4-oxazinan-2-yl)methylamine 90%

(4-Benzyl-1,4-oxazinan-2-yl)methylamine90%

1-[4-(Phenylmethyl)-2-morpholinyl]methanamine

2-Aminomethyl-4-benzylmorpholine

(4-benzyl-1,4-oxazinan-2-yl)MethanaMine

(4-Benzyl-2-Morpholinyl)MethanaMine

2-MorpholineMethanaMine, 4-(phenylMethyl)-

4-(Benzyl)-2-morpholinemethanamine

(4-Benzylmorpholin-2-yl)methylamine95+%

4-(Phenylmethyl)-2-morpholinemethanamine

(4-Benzyl-1,4-oxazinan-2-yl)methylamine, 2-(Aminomethyl)-4-benzylmorpholine

(4-Benzylmorpholin-2-yl)methylamine 90%

Mosapride Impurity 22

110859-47-7

pharmacetical

Aminomethyl's

Morpholines & Thiomorpholines

DCP