4,4-DIMETHYLCYCLOHEXYLAMINE
- Product Name
- 4,4-DIMETHYLCYCLOHEXYLAMINE
- CAS No.
- 20615-18-3
- Chemical Name
- 4,4-DIMETHYLCYCLOHEXYLAMINE
- Synonyms
- 4,4-DIMETHYLCYCLOHEXYLAMINE;4,4-DIMETHYLCYCLOHEXANAMINE;CyclohexylaMine,4,4-diMethyl-;CyclohexanaMine,4,4-diMethyl-;4,4-diMethylcyclohexan-1-aMine;4-AMINO-1,1-DIMETHYLCYCLOHEXANE
- CBNumber
- CB0353755
- Molecular Formula
- C8H17N
- Formula Weight
- 127.23
- MOL File
- 20615-18-3.mol
4,4-DIMETHYLCYCLOHEXYLAMINE Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- D456875
- Product name
- 4,4-Dimethylcyclohexan-1-amine
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CHM0377921
- Product name
- 4,4-DIMETHYLCYCLOHEXANAMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.32
- Updated
- 2021/12/16
- Product number
- 0566AB
- Product name
- 4,4-Dimethylcyclohexanamine
- Packaging
- 5g
- Price
- $971
- Updated
- 2021/12/16
- Product number
- A421546
- Product name
- 4,4-Dimethylcyclohexanamine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $66
- Updated
- 2021/12/16
- Product number
- A421546
- Product name
- 4,4-Dimethylcyclohexanamine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $102
- Updated
- 2021/12/16
4,4-DIMETHYLCYCLOHEXYLAMINE Chemical Properties,Usage,Production
Synthesis
4701-96-6
20615-18-3
The general procedure for the synthesis of 4,4-dimethylcyclohexylamine from 4,4-dimethylcyclohexanone oxime was as follows: 4,4-dimethylcyclohexanone oxime (10 g, 71 mmol, 1 equiv.) was dissolved in ethanol (100 mL) and Raney Ni catalyst (1 g, 10% w/w) was added. The reaction mixture was stirred under hydrogen atmosphere (50 psi) for 4 hours. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad. Hydrochloric acid (1 M in H2O, 100 mL, 100 mmol, 1.4 eq.) was added to the filtrate and the resulting precipitate was collected by filtration and dissolved in water. The aqueous phase was washed with ether and alkalized to a strong base with potassium hydroxide pellets and subsequently extracted twice with dichloromethane. The organic phases were combined, dried over magnesium sulfate and concentrated in vacuum to afford 4,4-dimethylcyclohexylamine (8 g, 89% yield) as a clear oil, which can be used in the next reaction without further purification.
References
[1] Patent: WO2004/50619, 2004, A1. Location in patent: Page 78-79
[2] Patent: WO2014/37900, 2014, A1. Location in patent: Page/Page column 33
[3] Journal of medicinal chemistry, 1971, vol. 14, # 17, p. 600 - 614
[4] Journal of the Chemical Society [Section] B: Physical Organic, 1971, p. 1047 - 1050
4,4-DIMETHYLCYCLOHEXYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
4,4-DIMETHYLCYCLOHEXYLAMINE Suppliers
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- Czech Republic
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