ChemicalBook > CAS DataBase List > 4,4-DIMETHYLCYCLOHEXYLAMINE

4,4-DIMETHYLCYCLOHEXYLAMINE

Product Name
4,4-DIMETHYLCYCLOHEXYLAMINE
CAS No.
20615-18-3
Chemical Name
4,4-DIMETHYLCYCLOHEXYLAMINE
Synonyms
4,4-DIMETHYLCYCLOHEXYLAMINE;4,4-DIMETHYLCYCLOHEXANAMINE;CyclohexylaMine,4,4-diMethyl-;CyclohexanaMine,4,4-diMethyl-;4,4-diMethylcyclohexan-1-aMine;4-AMINO-1,1-DIMETHYLCYCLOHEXANE
CBNumber
CB0353755
Molecular Formula
C8H17N
Formula Weight
127.23
MOL File
20615-18-3.mol
More
Less

4,4-DIMETHYLCYCLOHEXYLAMINE Property

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
Appearance
Colorless to light yellow Liquid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D456875
Product name
4,4-Dimethylcyclohexan-1-amine
Packaging
250mg
Price
$75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0377921
Product name
4,4-DIMETHYLCYCLOHEXANAMINE
Purity
95.00%
Packaging
5MG
Price
$495.32
Updated
2021/12/16
AK Scientific
Product number
0566AB
Product name
4,4-Dimethylcyclohexanamine
Packaging
5g
Price
$971
Updated
2021/12/16
Ambeed
Product number
A421546
Product name
4,4-Dimethylcyclohexanamine
Purity
97%
Packaging
100mg
Price
$66
Updated
2021/12/16
Ambeed
Product number
A421546
Product name
4,4-Dimethylcyclohexanamine
Purity
97%
Packaging
250mg
Price
$102
Updated
2021/12/16
More
Less

4,4-DIMETHYLCYCLOHEXYLAMINE Chemical Properties,Usage,Production

Synthesis

4701-96-6

20615-18-3

The general procedure for the synthesis of 4,4-dimethylcyclohexylamine from 4,4-dimethylcyclohexanone oxime was as follows: 4,4-dimethylcyclohexanone oxime (10 g, 71 mmol, 1 equiv.) was dissolved in ethanol (100 mL) and Raney Ni catalyst (1 g, 10% w/w) was added. The reaction mixture was stirred under hydrogen atmosphere (50 psi) for 4 hours. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad. Hydrochloric acid (1 M in H2O, 100 mL, 100 mmol, 1.4 eq.) was added to the filtrate and the resulting precipitate was collected by filtration and dissolved in water. The aqueous phase was washed with ether and alkalized to a strong base with potassium hydroxide pellets and subsequently extracted twice with dichloromethane. The organic phases were combined, dried over magnesium sulfate and concentrated in vacuum to afford 4,4-dimethylcyclohexylamine (8 g, 89% yield) as a clear oil, which can be used in the next reaction without further purification.

References

[1] Patent: WO2004/50619, 2004, A1. Location in patent: Page 78-79
[2] Patent: WO2014/37900, 2014, A1. Location in patent: Page/Page column 33
[3] Journal of medicinal chemistry, 1971, vol. 14, # 17, p. 600 - 614
[4] Journal of the Chemical Society [Section] B: Physical Organic, 1971, p. 1047 - 1050

4,4-DIMETHYLCYCLOHEXYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4,4-DIMETHYLCYCLOHEXYLAMINE Suppliers

China 49 Czech Republic 1 Germany 1 India 1 United States 8 USA 1 Global 61
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Anthem Pharmaceutical Research LLC
Tel
--
Fax
--
Email
sales@anthempharma.com
Country
United States
ProdList
3040
Advantage
30
Allichem LLC
Tel
--
Fax
--
Email
lib@umbi.umd.edu
Country
United States
ProdList
749
Advantage
30

20615-18-3, 4,4-DIMETHYLCYCLOHEXYLAMINERelated Search:

5-CHOLESTEN-3BETA-[N-PHENYL]AMINE Vincristine sulfate CONESSINE FUNTUMINE BASE 2,3-dimethylcyclohexylamine,mixtureofisomer N,N-Dimethylcyclohexylamine,98+%,N,N-Dimethylcyclohexylamine (DMCHA),N,N-DIMETHYLCYCLOHEXYLAMINE,Dimethylcyclohexylamine 7,7-AZO-3-A,12-A-DIHYDROXYTAUROCHOLANIC ACID, SODIUM SALT (+)-ISOPINOCAMPHEYLAMINE I-SAP (-)-ISOPINOCAMPHEYLAMINE 4,4-DIMETHYLCYCLOHEXYLAMINE HYDROCHLORIDE 2,6-DIMETHYLCYCLOHEXYLAMINE 2-(2-butoxyethoxy)ethyl dihydrogen phosphate, compound with N,N-dimethylcyclohexylamine 2-((4-CHLOROPHENYL)DIAZENYL)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE (25β)-3β-Amino-16α,23β-epoxy-16,28-seco-5α-solanidan-23-ol 5-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)ETHYL)-3,3-SPIRO-2-(5,5-DIMETHYL CYCLOHEXANE-1,3-DIONYL)DIHYDRO-2H-PYRROLO[3,4-D]ISOXAZOLE-4,6-(3H,5H)-DIONE SALOR-INT L202096-1EA 125I-SAP

  • 4-AMINO-1,1-DIMETHYLCYCLOHEXANE
  • 4,4-DIMETHYLCYCLOHEXYLAMINE
  • 4,4-diMethylcyclohexan-1-aMine
  • CyclohexanaMine,4,4-diMethyl-
  • CyclohexylaMine,4,4-diMethyl-
  • 4,4-DIMETHYLCYCLOHEXANAMINE
  • 20615-18-3