PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE

Product Name: PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
CAS No.: 207671-42-9
Chemical Name: PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
Synonyms: LUTIDINIC ACID MONOHYDRATE;PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE;2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE;2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE;PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE;2,4-Pyridinedicarboxylicacid, hydrate (1:1);2,4-Pyridinedicarboxylic acid Monohydrate 98%
CBNumber: CB0356837
Molecular Formula: C7H7NO5
Formula Weight: 185.13
MOL File: 207671-42-9.mol

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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Property

Melting point:: 246-248 °C (dec.)(lit.)
storage temp.: Store at -20°C
solubility: DMSO: 1.4 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form: A crystalline solid
BRN: 131631

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P63395
Product name: 2,4-Pyridinedicarboxylic acid monohydrate
Purity: 98%
Packaging: 5g
Price: $48.6
Updated: 2024/03/01

Cayman Chemical

Product number: 11138
Product name: 2,4-Pyridinedicarboxylic Acid (hydrate)
Packaging: 1g
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 11138
Product name: 2,4-Pyridinedicarboxylic Acid (hydrate)
Packaging: 5g
Price: $122
Updated: 2024/03/01

Usbiological

Product number: 287422
Product name: 2,4-Pyridinedicarboxylic acid monohydrate
Packaging: 2g
Price: $180
Updated: 2021/12/16

TRC

Product number: P992035
Product name: 2,4-Pyridinedicarboxylic acid monohydrate
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Chemical Properties,Usage,Production

Description

2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. As a 2-OG mimic, it blocks the activity of 2-OG oxygenases, which include certain lysine demethylases and a variety of hydroxylases (e.g., prolyl, collagen, lysyl). 2,4-PDCA inhibits several Jumonji domain-containing lysine demethylases when used at low micromolar concentrations. Through its effects on hydroxylases, including prolyl hydroxlase 1 (IC₅₀ = 1.5 μM), 2,4-PDCA modulates hypoxia-inducible factor turnover, collagen synthesis, and plant cell wall formation. It can inhibit zinc-dependent enzymes, like metallo-β-lactamase. 2,4-PDCA also affects and is translocated by organic anion transporters.

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Suppliers

China 30 France 1 Germany 1 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 2 United States 10 Global 47

Energy Chemical

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Shandong Xiya Chemical Co., Ltd

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Shanghai Na Qian Chemical Technology Co. Ltd.

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Sigma-Aldrich

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BOC Sciences

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Shanghai Qiao Chemical Science Co., Ltd

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Chengdu Dianchun Technology Co., Ltd

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Amadis Chemical Company Limited

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207671-42-9, PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATERelated Search:

2,2'-Bipyridine-5,5'-dicarboxylic acid 3,4-Pyridinedicarboxylic acid Pyridine-2,4,6-tricarboxylic acid 4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester 7,9-DIMETHOXYCARBONYL-2-ETHOXYCARBONYL-5-METHOXY-1H-PYRROLO-[2,3-F]QUINOLINE 7,9-DIMETHOXYCARBONYL-2-ETHOXYCARBONYL-1H-PYRROLO-[2,3-F]QUINOLINE-4,5-DIONE 4,5-DIHYDRO-4,5-DIOXO-1H-PYRROLO[2,3-F]QUINOLINE-2,7,9-TRICARBOXYLIC ACID, 5,5-DIMETHYL KETAL PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Pyrroloquinoline quinone TRIMETHYL 5-HYDROXY-2,3,4-PYRIDINETRICARBOXYLATE Pyrroloquinoline quinone disodium salt

PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE

2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE

2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE

LUTIDINIC ACID MONOHYDRATE

2,4-Pyridinedicarboxylicacid, hydrate (1:1)

2,4-Pyridinedicarboxylic acid Monohydrate 98%

207671-42-9

C7H5NO4H2O

Building Blocks

C7 and C8

Heterocyclic Building Blocks

Pyridines

Building Blocks

C7

Chemical Synthesis

Heterocyclic Building Blocks

C7 and C8

Heterocyclic Building Blocks

Pyridines