ChemicalBook > CAS DataBase List > 8-GINGEROL

8-GINGEROL

Product Name: 8-GINGEROL
CAS No.: 23513-08-8
Chemical Name: 8-GINGEROL
Synonyms: (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone;8-Gingerol;GINGEROL [8];8-Gingerol-RM;8-Gingerol ,98%;(s)-(+)-3-dodecanon;8-GINGEROL USP/EP/BP;Glycerol Impurity 35;[8]-Gingerol Standard;8]-Gingerol >=95% (HPLC)
CBNumber: CB0359494
Molecular Formula: C19H30O4
Formula Weight: 322.44
MOL File: 23513-08-8.mol

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8-GINGEROL Property

Boiling point:: 476.4±35.0 °C(Predicted)
Density: 1.058±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: methanol: soluble1mg/mL, clear, colorless
pka: 10.02±0.20(Predicted)
form: powder
color: white to light yellow
Water Solubility: practically insoluble in water
BRN: 2059802
InChI: InChI=1S/C19H30O4/c1-3-4-5-6-7-8-16(20)14-17(21)11-9-15-10-12-18(22)19(13-15)23-2/h10,12-13,16,20,22H,3-9,11,14H2,1-2H3/t16-/m0/s1
InChIKey: BCIWKKMTBRYQJU-INIZCTEOSA-N
SMILES: C(C1=CC=C(O)C(OC)=C1)CC(=O)C[C@@H](O)CCCCCCC
LogP: 3.881 (est)

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
WGK Germany: 3
RTECS: JR4362000
HS Code: 29145019

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G5923
Product name: [8]-Gingerol
Purity: ≥95% (HPLC)
Packaging: 5mg
Price: $276
Updated: 2025/07/31

Sigma-Aldrich

Product number: 01514
Product name: [8]-Gingerol
Purity: analytical standard
Packaging: 10mg
Price: $686
Updated: 2025/07/31

Cayman Chemical

Product number: 11841
Product name: 8-Gingerol
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 11841
Product name: 8-Gingerol
Purity: ≥98%
Packaging: 5mg
Price: $166
Updated: 2024/03/01

Sigma-Aldrich

Product number: G5923
Product name: [8]-Gingerol
Purity: ≥95% (HPLC)
Packaging: 10mg
Price: $524
Updated: 2023/06/20

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8-GINGEROL Chemical Properties,Usage,Production

Chemical Properties

A white waxy solid, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from dried ginger and fresh ginger.

Uses

8-Gingerol has been observed to exhibit anti-oxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation.

Definition

ChEBI: (8)-Gingerol is a beta-hydroxy ketone, a member of phenols and a monomethoxybenzene.

Biological Activity

[8]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.

in vivo

8-Gingerol (50, 100 mg/kg, i.p., once daily for 7 days) can suppress the humoral and cellular immune responses in mice, likely by directly inhibiting activated T cells and B cells^[4]. 8-Gingerol (10, 20 mg/kg, i.p., once daily for 14 days) improves ISO-induced myocardial fibrosis in mice by regulating the PI3K/Akt/mTOR signaling pathway, inhibiting oxidative stress, apoptosis, and autophagy^[5].

Animal Model:	OVA-immunized mice (BALB/c male mice, 5 weeks old, 18-22g, immunized with ovalbumin (OVA))^[4]
Dosage:	25, 50, 100 mg/kg
Administration:	Intraperitoneal injection (i.p.), once daily for 7 consecutive days
Result:	Significantly suppressed LPS-, ConA-, and OVA-induced splenocyte proliferation in OVA-immunized mice and significantly reduced the percentage of CD19+ B cells and CD3+ T cells at high doses (50, 100 mg/kg)

Animal Model:	Isoproterenol (ISO)-induced myocardial fibrosis (MF) mouse model, Kunming mice (male, 6-8 weeks old, 15-20g)^[5]
Dosage:	10 mg/kg (low dose), 20 mg/kg (high dose)
Administration:	Intraperitoneal injection (i.p.), once daily for 14 days
Result:	Significantly reduced the heart weight, left ventricle weight index, CK, LDH levels, ROS generation, and pathological heart damage induced by ISO.

IC 50

MMP-9; Caspase-9

8-GINGEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-GINGEROL manufacturers

Shanghai Standard Technology Co., Ltd.

Product: 8-Gingerol 23513-08-8
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-31

Zhuozhou Wenxi import and Export Co., Ltd

Product: 8-GINGEROL 23513-08-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 8-GINGEROL 23513-08-8
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-09

23513-08-8, 8-GINGEROLRelated Search:

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GINGEROL [8]

(5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxydodecane-3-one

(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone

(S)-10-Oxo-12-(3-methoxy-4-hydroxyphenyl)dodecane-8-ol

8-Gingerol ,98%

(5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one

(s)-(+)-3-dodecanon

(s)-(+)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone

8-Gingerol, 98%, from Zingiber officinale Roscoe

5-HYDROXY-1-(4-HYDROXY-3-METHOXYPHENYL)-3-DODECANONE

[8]-Gingerol Standard

3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-

8]-Gingerol >=95% (HPLC)

8-GINGEROL USP/EP/BP

(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one

8-Gingerol

8-Gingerol-RM

Glycerol Impurity 35

8-Gingerol, 10 mM in DMSO

23513-08-8

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