ARG-GLY-ASP

Product Name: ARG-GLY-ASP
CAS No.: 99896-85-2
Chemical Name: ARG-GLY-ASP
Synonyms: RGD;F-336;H2N-RGD-OH;ARG-GLY-ASP;L-ARG-GLY-ASP;H-ARG-GLY-ASP-OH;RGD (Arg-Gly-Asp);Arg-Gly-Asp (TLC);RGD PEPTIDE (CORE);Arg-Gly-Asp acetate
CBNumber: CB0364876
Molecular Formula: C12H22N6O6
Formula Weight: 346.34
MOL File: 99896-85-2.mol

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ARG-GLY-ASP Property

Melting point:: 153-155℃ (ethyl ether )
Density: 1.61±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in 0.1N acetic acid at 20mg/ml
pka: 2.85±0.10(Predicted)
form: Powder
Water Solubility: Soluble to 12 mg/mL (34.64 mM) in Water
InChIKey: IYMAXBFPHPZYIK-BQBZGAKWSA-N

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A8052
Product name: Arg-Gly-Asp
Purity: ≥97% (TLC)
Packaging: 1mg
Price: $34.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: A8052
Product name: Arg-Gly-Asp
Purity: ≥97% (TLC)
Packaging: 5mg
Price: $101
Updated: 2024/03/01

Alfa Aesar

Product number: J65468
Product name: Arg-Gly-Asp
Packaging: 5mg
Price: $164
Updated: 2023/06/20

Sigma-Aldrich

Product number: A8052
Product name: Arg-Gly-Asp
Purity: ≥97% (TLC)
Packaging: 10mg
Price: $182
Updated: 2024/03/01

Usbiological

Product number: 260168
Product name: Arg-Gly-Asp
Packaging: 50mg
Price: $305
Updated: 2021/12/16

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ARG-GLY-ASP Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Arg-Gly-Asp has been used:

to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogel
in adhesion assay
in inhibition assay to confirm the β1-integrin-dependency of cell adhesion
in textile fabrication and RGD textile functionalization
to engineer a population of human dermal fibroblasts with impaired migration
to modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)
in the cell culture of human mammary epithelial cells

Definition

ChEBI: Arg-Gly-Asp is an oligopeptide.

General Description

Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.

Biological Activity

synthetic peptides containing the arginine-glycine-aspartate (rgd) were extensively used as inhibitors of integrin-ligand interactions in studies of cell adhesion, migration, growth and differentiation, since the rgd motif is an integrin-recognition motif found in many ligands.

Biochem/physiol Actions

Primary sequence involved with the binding of proteins to cell surfaces

in vitro

rgd peptide can induce apoptosis in the absence of signals and integrin-mediated cell clustering. previous study demonstrates that rgd peptides promote apoptosis through activation of conformation changes enhancing pro-caspase-3 activation and autoprocessing [1].

in vivo

anima study suggested that the rgd-4c-fitc-peptide bound to both endothelial and tumor cells in vivo and that peptide targeting should allow the delivery of therapeutic drugs to both endothelial and tumor cells [2].

target

integrin-ligand interaction

storage

Store at -20°C

References

[1] nature. 1999 feb 11;397(6719):534-9.rgd peptides induce apoptosis by direct caspase-3 activation. buckley cd1, pilling d, henriquez nv, parsonage g, threlfall k, scheel-toellner d, simmons dl, akbar an, lord jm, salmon m.
[2] cancer res. 2002 sep 15;62(18):5139-43. arginine-glycine-aspartic acid (rgd)-peptide binds to both tumor and tumor-endothelial cells in vivo. zitzmann s1, ehemann v, schwab m.

ARG-GLY-ASP Preparation Products And Raw materials

Raw materials

Preparation Products

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ARG-GLY-ASP Suppliers

China 151 China Hong Kong 1 France 1 Germany 3 India 1 Japan 2 Switzerland 1 United Kingdom 4 United States 21 Global 185

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: eric@peptidego.com
Country: China
ProdList: 6119
Advantage: 58

Zhejiang Jiekun Biotechnology Co., Ltd

Tel: 0571-88211951 13735575465
Email: sales1@gotopbio.com
Country: China
ProdList: 4904
Advantage: 58

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

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View Lastest Price from ARG-GLY-ASP manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: ARG-GLY-ASP 99896-85-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Hebei Xinsheng New Material Technology Co., LTD.

Product: Arg-Gly-Asp
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-08-22

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Arginyl-glycyl-aspartic acid 99896-85-2
Price: US $90.00-900.00/KG
Min. Order: 1KG
Purity: 0.98
Supply Ability: 20 tons
Release date: 2023-10-25

99896-85-2, ARG-GLY-ASPRelated Search:

L-Glutamic acid, N-(N-L-arginylglycyl)- H-ARG-GLY-ASP-VAL-OH L-ARG-GLY-ASP-SER,H-ARG-GLY-ASP-SER-OH THYMOPOIETIN II (32-34) H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH H-GLY-ARG-GLY-ASP-SER-PRO-CYS-OH H-GLY-ARG-GLY-ASP-SER-OH GLY-PEN-GLY-ARG-GLY-ASP-SER-PRO-CYS-ALA H-ALA-CYS-ASP-CYS-ARG-GLY-ASP-CYS-PHE-CYS-GLY-OH (DISULFIDE BRIDGE: 2-10 AND 4-8) H-ARG-GLY-ASP-CYS-OH H-ARG-ARG-GLY-ASP-MET-GLU-OH H-GLY-ARG-GLY-ASP-THR-PRO-OH,GLY-ARG-GLY-ASP-THR-PRO H-GLY-ARG-GLY-ASP-ASN-PRO-OH SAR-ARG-GLY-ASP-SER-PRO,SAR-ARG-GLY-ASP-SER-PRO-OH TRP-ASN-ARG-GLN-LEU-TYR-PRO-GLU-TRP-THR-GLU-ALA-GLN-ARG-LEU-ASP ARG-GLY-ASP HIS-GLN-VAL-SER-LEU-SER-LYS-GLN-PRO-THR-SER-GLN-PRO-ARG-GLY-ASP H-GLY-ARG-GLY-ASP-OH

H2N-RGD-OH

H-ARG-GLY-ASP-OH

L-ARG-GLY-ASP

ARGINYL-GLYCYL-ASPARTIC ACID

ARG-GLY-ASP

ARG-GLY-ASP PEPTIDE

Arg-Gly-Asp acetate

Arginyl-glycyl-asparagilin

F-336

L-Aspartic acid, N-(N-L-arginylglycyl)-

N-(N-L-Arginylglycyl)-L-aspartic acid

Rgd tripeptide sequence

RGD (Arg-Gly-Asp) Peptides

Arginyl - glycyl - aspartate

L-Arginylglycyl-L-aspartic acid

RGD

RGD PEPTIDE (CORE)

L-Aspartic acid, L-arginylglycyl-

H-Arg-Gly-Asp-OH≥ 98% (HPLC)

Arg-Gly-Asp, ≥97% (HPLC)

Arg-Gly-Asp >=97% (TLC)

ARG-GLY-ASP USP/EP/BP

(S)-2-(2-((S)-2-Amino-5-guanidinopentanamido)acetamido)succinic acid

RGD (Arg-Gly-Asp)

Arg-Gly-Asp (TLC)

Integrin,RGD,inhibit,Inhibitor

99896-85-2

C12H22N6O6

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