CARDIOTROPHIN-1, HUMAN
- Product Name
- CARDIOTROPHIN-1, HUMAN
- Chemical Name
- CARDIOTROPHIN-1, HUMAN
- Synonyms
- RHCT-1;HUMAN CT-1;CARDIOTROPHIN-1;HUMAN CARDIOTROPHIN-1;CARDIOTROPHIN-1, HUMAN;RECOMBINANT HUMAN CARDIOTROPHIN-1;CARDIOTROPHIN-1, HUMAN, RECOMBINANT;CARDIOTROPHIN-1, HUMAN, RECOMBINANT, E COLI
- CBNumber
- CB0369149
- Formula Weight
- 0
- MOL File
- Mol file
CARDIOTROPHIN-1, HUMAN Property
- storage temp.
- -20°C
- form
- lyophilized
- biological source
- human
Safety
- WGK Germany
- WGK 3
- Storage Class
- 13 - Non Combustible Solids
N-Bromosuccinimide Price
- Product number
- SRP4011
- Product name
- Cardiotrophin-1 human
- Purity
- recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
- Packaging
- 10μG
- Price
- $387
- Updated
- 2024/03/01
- Product number
- C1385-06
- Product name
- Cardiotrophin 1, Human, Recombinant
- Packaging
- 2ug
- Price
- $269
- Updated
- 2021/12/16
- Product number
- C1385-06B
- Product name
- Cardiotrophin 1, Human, Recombinant
- Packaging
- 2ug
- Price
- $297
- Updated
- 2021/12/16
- Product number
- 153845
- Product name
- Cardiotrophin 1
- Packaging
- 10ug
- Price
- $356
- Updated
- 2021/12/16
- Product number
- 153846
- Product name
- Cardiotrophin 1
- Packaging
- 10ug
- Price
- $366
- Updated
- 2021/12/16
CARDIOTROPHIN-1, HUMAN Chemical Properties,Usage,Production
Uses
Cardiotrophin-1 belongs to the interleukin-6 (IL-6) family of cytokines. It is a cytoprotective protein. The gene is mapped to human chromosome 16p11.
Recombinant human Cardiotrophin-1 is a 22.5kDa protein containing 200 amino acid residues.
Biological Activity
Cardiotrophin-1 signals via β receptor glycoprotein 130 (gp130) and β receptor leukemia inhibitory factor receptor (LIFR). It confers protective role on cardiac myocytes. Cardiotrophin-1 protects cardiomyocytes from cell death, however, it can also induce cardiac hypertrophy. It is also involved in neural tissue development and helps in protection of the mature nervous system from injuries and dysfunction. Cardiotrophin-1 also protects liver against injury. It is also involved in the control of body weight and intermediate metabolism. In mouse model, it protects β cells from apoptosis. It also promotes glucose-mediated insulin secretion. Absence of the cardiotrophin-1 gene in mice is associated with obesity, hyperglycemia, hyperinsulinemia and hypercholesterolemia.
CARDIOTROPHIN-1, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
CARDIOTROPHIN-1, HUMAN Suppliers
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