Sulbactam sodium
- Product Name
- Sulbactam sodium
- CAS No.
- 69388-84-7
- Chemical Name
- Sulbactam sodium
- Synonyms
- Sodium Sodium;Sulbatam Sodium;SODIUM SULBACTAM;Sterile Sulbactam sodium;(2S,5R);CP-45899-2;Shu ba sodium;sulbacyam sodium;SULBACTAM SODIUM;cp45899sodiumsalt
- CBNumber
- CB0370356
- Molecular Formula
- C8H12NNaO5S
- Formula Weight
- 257.24
- MOL File
- 69388-84-7.mol
Sulbactam sodium Property
- Melting point:
- >230°C (dec.)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids.
- color
- White
- InChIKey
- NKZMPZCWBSWAOX-IBTYICNHSA-M
- CAS DataBase Reference
- 69388-84-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 42/43
- Safety Statements
- 22-24-36/37-45-24/25
- HS Code
- 29349990
- Toxicity
- LD50 ivn-rat: 6500 mg/kg NKRZAZ 32(Suppl 4),97,84
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Y0000529
- Product name
- Sulbactam sodium
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0000529
- Price
- $220
- Updated
- 2024/03/01
- Product number
- S699185
- Product name
- SulbactamSodiumSalt
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- S699185
- Product name
- SulbactamSodiumSalt
- Packaging
- 2g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- J11108
- Product name
- Sulbactam sodium
- Packaging
- 25mg
- Price
- $20
- Updated
- 2021/12/16
- Product number
- J95709
- Product name
- Sulbactam sodium
- Packaging
- 1g
- Price
- $62
- Updated
- 2021/12/16
Sulbactam sodium Chemical Properties,Usage,Production
Description
Sulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.
Chemical Properties
White Solid
Originator
Pfizer (USA)
Uses
A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.
Definition
ChEBI: Sulbactam sodium is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Manufacturing Process
Sulbactam sodium is semi-synthetic antibiotic of penicillinic group. Start
material for it's synthesis is 6-aminopenicillanic acid. First 6-aminopenicillanic
acid was isolated in 1957 year from benzylpenicilline as resalt of treating of it
by penicillinaze. Benzylpenicilline is produced by microorganism of genus
Streptomyces.
Further, 6-aminopenicillanic acid reacted with bromine, hydrochloric acid and
NaNO2. As a result the 6,6-dibromopenicillanic acid was obtained.
6,6-Dibromopenicillanic acid was oxidized by KMnO4, to give 6,6-dibromo-1,1-The 6,6-dibromo-1,1-dioxopenicillanic acid in presence of Fe was converted to
the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was
treated by sodium 2-ethylhexanoate and crude sulbactam sodium was
obtained.
brand name
SULPERAZONE
Therapeutic Function
Beta-lactamase inhibitor
General Description
Sulbactam was synthesized by Pfizer Research Laboratories in 1977 in the course of screening for β-lactamase inhibitors. It shows strong activity against penicillinase and moderate activity against cephalosporinase. Sulbactam itself shows activity against some gramnegative bacteria but no activity against most pathogenic bacteria. The use of sulbactam in combination with cefoperazone, which is partially hydrolyzed by penicillinase, is under study along with its use as an esterified complex with ampicillin (sultamicillin) for therapy of cefoperazone-ampicillin-resistant infections.
Safety Profile
Poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx
Sulbactam sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Sulbactam sodium manufacturers
- Product
- Sulbactam sodium 69388-84-7
- Price
- US $20.00/KG
- Min. Order
- 10KG
- Purity
- 99%
- Supply Ability
- 1000KG/day
- Release date
- 2024-02-28
- Product
- Sulbactam sodium 69388-84-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2024-04-03
- Product
- Cefoperazone Sodium+Sulbactam Sodium 69388-84-7
- Price
- US $0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99%
- Supply Ability
- 10kg
- Release date
- 2024-04-09