ChemicalBook > CAS DataBase List > Lercanidipine hydrochloride

Lercanidipine hydrochloride

Product Name
Lercanidipine hydrochloride
CAS No.
132866-11-6
Chemical Name
Lercanidipine hydrochloride
Synonyms
LERCANIDIPINE HCL;CLAP;mE10;R 75;BCL10;c-E10;CIPER;CarMen;Lercan;LerzaM
CBNumber
CB0371085
Molecular Formula
C36H42ClN3O6
Formula Weight
648.19
MOL File
132866-11-6.mol
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Lercanidipine hydrochloride Property

Melting point:
175-177°C
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
powder
color 
yellow
Merck 
14,5446
InChIKey
WMFYOYKPJLRMJI-UHFFFAOYSA-N
CAS DataBase Reference
132866-11-6(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
36/37-45
RIDADR 
UN 2811
WGK Germany 
3
HS Code 
2933.39.4100
Toxicity
LD50 in mice (mg/kg): 83 i.p.; 657 orally (Nardi)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L6668
Product name
Lercanidipine hydrochloride
Purity
≥98% (HPLC)
Packaging
10mg
Price
$122.4
Updated
2024/03/01
Sigma-Aldrich
Product number
L6668
Product name
Lercanidipine hydrochloride
Purity
≥98% (HPLC)
Packaging
50mg
Price
$643
Updated
2024/03/01
TCI Chemical
Product number
L0282
Product name
Lercanidipine Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
L0282
Product name
Lercanidipine Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$44
Updated
2024/03/01
Alfa Aesar
Product number
H36728
Product name
Lercanidipine hydrochloride
Purity
98%
Packaging
1g
Price
$327.65
Updated
2024/03/01
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Lercanidipine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Pale-Yellow Powder

Uses

long-acting dihydropyridine calcium channel blocker, antihypertensive

Uses

A dihydropyridine calcium channel blocker. Antihypertensive.

Definition

ChEBI: Lercanidipine hydrochloride is a diarylmethane.

brand name

Cardiovasc (Recor dati, Italy); Carmen (Recordati, Italy); Corifeo (Recordati, Italy); Lercadip (Recordati, Italy); Lercan (Recordati, Italy); Lercapin (Recordati, Italy); Lercaton (Recordati, Italy); Lerkamen (Recordati, Italy); Lerzam (Recordati, Italy); Renovia (Recordati, Italy); Vasodip (Recordati, Italy); Zandip (Recordati, Italy); Zanicor (Recordati, Italy).

Biological Activity

L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.

Biochem/physiol Actions

Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Lercanidipine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Lercanidipine hydrochloride Suppliers

Americas 1 Canada 3 China 257 Cyprus 1 Europe 2 France 2 Germany 1 Hungary 1 India 40 Japan 1 Malaysia 1 South Korea 5 Switzerland 1 United Kingdom 12 United States 37 Global 365
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View Lastest Price from Lercanidipine hydrochloride manufacturers

Hangzhou Hyper Chemicals Limited
Product
Lercanidipine hydrochloride 132866-11-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2024-08-30
Hebei Yanxi Chemical Co., Ltd.
Product
Lercanidipine hydrochloride 132866-11-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-07
Hebei Yanxi Chemical Co., Ltd.
Product
Lercanidipine hydrochloride 132866-11-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-07

132866-11-6, Lercanidipine hydrochlorideRelated Search:

Dimethyl carbonate Lercanidipine Quinolinic acid Dimethyl phthalate ETHANE Dacthal 2,6-Lutidine 2,5-PYRIDINEDICARBOXYLIC ACID Dimethyl fumarate Dimethyl disulfide N,N-Dimethylallylamine Topotecan hydrochloride 2,5-Dimethylpyridine Chromium picolinate Dimethyl sulfate DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Dimethyl sulfoxide 1-AdaMantanethylaMine

  • 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride
  • LERCANIDIPINE HCL
  • LERCANIDIPINE HYDROCHLORIDE
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylicAcid2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimeth
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
  • 3-(1-((3,3-Diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
  • 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)MethylaMino]-1,1-diMethylethyl] 5-Methyl ester,hydrochloride (1:1)
  • Lercanidipine Impurity 1
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride
  • B-cell CLL/lymphoma 10
  • B-cell lymphoma/leukemia 10
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  • -1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
  • -2-methylpropan-2-yl)
  • 3-(1-((3,3-Diphenylpropyl)
  • 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)
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  • Lercanidipine hemihydrate hydrochloride
  • 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-[2-[3,3-diphenylpropyl(methyl)amino]-1,1-dimethyl-ethyl] ester O5-methyl ester hydrochloride
  • 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
  • O3-[1-[3,3-diphenylpropyl(methyl)amino]-2-methyl-propan-2-yl] O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
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