ChemicalBook > CAS DataBase List > 4H-PYRAN-4-ONE

4H-PYRAN-4-ONE

Product Name
4H-PYRAN-4-ONE
CAS No.
108-97-4
Chemical Name
4H-PYRAN-4-ONE
Synonyms
4-Pyrone;Pyrocoman;PYRAN-4-ONE;GAMMA-PYRONE;4H-PYRAN-4-ONE;4H-Pyran, 4-oxo-;4H-Pyran-4-one>4H-PYRAN-4-ONE, 98+%;4H-Pyran-4-one;GAMMA-PYRONE, 4-PYRONE
CBNumber
CB0376459
Molecular Formula
C5H4O2
Formula Weight
96.08
MOL File
108-97-4.mol
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4H-PYRAN-4-ONE Property

Melting point:
32-34 °C(lit.)
Boiling point:
210-215 °C(lit.)
Density 
1.20
refractive index 
1.5238
Flash point:
214 °F
storage temp. 
2-8°C
solubility 
Slightly soluble in water, soluble in alcohol and oils.
form 
clear liquid
color 
Light yellow to Brown
Odor
Warm, slight ly pungent, hay-like herbaceous odor of moderate to poor tenacity.
BRN 
105293
Stability:
Polymerizes under exposure to air (oxygen) and alkali. Turns darker brown, and its odor fades.
InChIKey
CVQUWLDCFXOXEN-UHFFFAOYSA-N
LogP
-0.628 (est)
CAS DataBase Reference
108-97-4
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
3-8-10
HS Code 
2932.99.9090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
177229
Product name
4H-Pyran-4-one
Purity
≥98%
Packaging
1g
Price
$64
Updated
2025/07/31
Sigma-Aldrich
Product number
177229
Product name
4H-Pyran-4-one
Purity
≥98%
Packaging
5g
Price
$520
Updated
2025/07/31
TCI Chemical
Product number
P1450
Product name
4H-Pyran-4-one
Purity
>98.0%(GC)
Packaging
1g
Price
$184
Updated
2025/07/31
TCI Chemical
Product number
P1450
Product name
4H-Pyran-4-one
Purity
>98.0%(GC)
Packaging
5g
Price
$736
Updated
2025/07/31
TRC
Product number
P840695
Product name
4H-Pyran-4-one
Packaging
500mg
Price
$240
Updated
2021/12/16
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4H-PYRAN-4-ONE Chemical Properties,Usage,Production

Uses

4H-Pyran-4-one was used in the synthesis of probes grafted on the lipid headgroups.

Preparation

1) from Diethylacetone dioxalate by cyclization to Chelidonic acid (gamma-Pyrone- 2,6-dicarboxylic acid). The acid yields 4H-Pyran-4-one by decarboxylation.
2) by heating of I-Methoxypent-l -en-3-yn-5- al diethylacetal with Methanol and water, using Mercuric sulfate or Sulfuric acid catalyst.

Definition

ChEBI: A pyranone that is 4H-pyran substituted by an oxo group at position 4.

Synthesis

159015-78-8

108-97-4

Example 1 (Synthesis of pyran-4-one): In a 10 mL glass reaction flask fitted with a stirring device and a dropping funnel, 1.0 g (4.8 mmol) of 1,1,5,5-tetramethoxypentan-3-one (CAS: 159015-78-8) was added. Under cooling in an ice bath, 1.2 mL (14.1 mmol) of 12 mol/L hydrochloric acid solution was slowly added dropwise to the reaction flask. After the dropwise addition, the reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, the reaction solution was analyzed by gas chromatography (internal standard method) to confirm the formation of 0.45 g (yield: 97%) of pyran-4-one.

Purification Methods

Purify -pyrone by vacuum distillation; the distillate crystallises and is hygroscopic. It is non-steam vola

References

[1] Patent: EP1700853, 2006, A1. Location in patent: Page/Page column 12
[2] Patent: EP1700853, 2006, A1. Location in patent: Page/Page column 12

4H-PYRAN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4H-PYRAN-4-ONE Suppliers

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View Lastest Price from 4H-PYRAN-4-ONE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4H-PYRAN-4-ONE 108-97-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Dideu Industries Group Limited
Product
4H-PYRAN-4-ONE 108-97-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-29
Career Henan Chemical Co
Product
4H-PYRAN-4-ONE 108-97-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
KG/T
Release date
2019-12-19

108-97-4, 4H-PYRAN-4-ONERelated Search:

2,6-Dimethyl-4H-pyran-4-one Maltol isobutyrate Kojic acid Maltol propionate 3-Hydroxy-2-methyl-4H-pyran-4-one 4H-Pyran-4-one,2-ethyl-3-hydroxy 4-O-BETA-D-GULCOSYL-5-O-METHYLVISAMMINOL Warfarin Isorhamnetin 3-Chromanone NABILONE-DEA SCHEDULE II Scopoletin DIHYDROKAVAIN Dihydrokawain (+/-)-6-PENTYLTETRAHYDRO-2H-PYRAN-2-ONE FLAVONE Difenacoum TETRAHYDRO-6-PROPYL-2H-PYRAN-2-ONE

  • 4H-PYRAN-4-ONE
  • GAMMA-PYRONE
  • GAMMA-PYRONE, 4-PYRONE
  • PYRAN-4-ONE
  • 4H-Pyran, 4-oxo-
  • 4H-PYRAN-4-ONE, 98+%
  • 4-Pyrone
  • Pyrocoman
  • 4<i>H</i>-Pyran-4-one
  • 4H-Pyran-4-one&gt
  • 4H-PYRAN-4-ONE ISO 9001：2015 REACH
  • ethyl4-(4-methoxy-3-methylphenyl)-2,6-dioxobutanoate
  • 108-97-4
  • Heterocyclic Building Blocks
  • Pyrans
  • Building Blocks