Dihydrokawain

Product Name: Dihydrokawain
CAS No.: 587-63-3
Chemical Name: Dihydrokawain
Synonyms: MARINDININ;DIHYDROKAVAIN;DIHYDROKAWAIN;dihydro-kawai;DIHYDROKAWAIN;DIHYDROKAVAIN(P);7,8-Dihydrokavain;7,8-DIHYDROKAWAIN;(S)-(+)-7,8-Dihydrokavain;Dihydrokavain (7,8-Dihydrokawain
CBNumber: CB4314738
Molecular Formula: C14H16O3
Formula Weight: 232.27
MOL File: 587-63-3.mol

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Dihydrokawain Property

Melting point:: 58-60°
alpha: D24 +31° (methanol)
Boiling point:: 314.44°C (rough estimate)
Density: 1.1649 (rough estimate)
refractive index: 1.5557 (estimate)
storage temp.: 2-8°C
solubility: DMF:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);21.52(Max Conc. mM)
optical activity: [α]/D 29±2°, c = 0.5 in methanol
BRN: 15362
InChIKey: VOOYTQRREPYRIW-LBPRGKRZSA-N
LogP: 1.950 (est)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 41866
Product name: (S)-(+)-7,8-Dihydrokavain
Purity: analytical standard
Packaging: 5mg
Price: $539
Updated: 2022/05/15

Usbiological

Product number: 361778
Product name: Dihydrokawain
Packaging: 10mg
Price: $581
Updated: 2021/12/16

TRC

Product number: D450620
Product name: (+)-(S)-Dihydrokavain
Packaging: 1mg
Price: $185
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD76571
Product name: Dihydrokawain
Packaging: 10mg
Price: $250
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0000214
Product name: DIHYDROKAVAIN
Purity: 95.00%
Packaging: 5MG
Price: $713.26
Updated: 2021/12/16

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Dihydrokawain Chemical Properties,Usage,Production

Chemical Properties

White-pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of kava-kava (Piper methysticum G. Forst).

Uses

(+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.

Definition

ChEBI: Dihydrokavain is a member of 2-pyranones and an aromatic ether.

Application

Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.Used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.

Preparation

Starting from 2,3-O-isopropylidene-D-glyceraldehyde (2) as chiral material, the naturally occurring (S)-(+)-dihydrokavain (1a) was synthesized by a procedure that involves a sonochemical Blaise reaction as the key step. The absolute configuration of (S)-(+)-dihydrokavain (1a) is demonstrated for the first time by total synthesis from a chiral source. Its opposite enantiomer, (R)-(–)-dihydrokavain (1b), was also synthesized after inversion of the chiral center in a Mitsunobu reaction.
A Total Synthesis of (+)- and (–)-Dihydrokavain with a Sonochemical Blaise Reaction as the Key Step

Dihydrokawain Preparation Products And Raw materials

Raw materials

Preparation Products

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Dihydrokawain Suppliers

China 103 United Kingdom 3 United States 15 Global 121

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Chengdu Herbpurify Co.Ltd.

Tel: 18302802153 18981717076
Fax: 086-28-85377358
Email: 2355253619@qq.com
Country: China
ProdList: 1104
Advantage: 58

Shanghai Zhanshu Chemical Technology Co., Ltd

Tel: +86-21-58589556
Fax: +86-21-58589557
Country: China
ProdList: 413
Advantage: 55

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View Lastest Price from Dihydrokawain manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Dihydrokavain 587-63-3
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-27

Career Henan Chemical Co

Product: DIHYDROKAVAIN 587-63-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-18

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587-63-3

Coumarins