LICOCHALCONE-A

Product Name: LICOCHALCONE-A
CAS No.: 58749-22-7
Chemical Name: LICOCHALCONE-A
Synonyms: CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;Licochalcone A-RM;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Licochalcone A (10mg)
CBNumber: CB5114580
Molecular Formula: C21H22O4
Formula Weight: 338.4
MOL File: 58749-22-7.mol

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LICOCHALCONE-A Property

Melting point:: 100°
Boiling point:: 532.6±50.0 °C(Predicted)
Density: 1.171±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka: 7.82±0.15(Predicted)
form: Yellow solid
color: Yellow-orange
BRN: 4534154
InChI: InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
InChIKey: KAZSKMJFUPEHHW-DHZHZOJOSA-N
SMILES: C(C1=CC=C(O)C=C1)(=O)/C=C/C1=CC(C(C)(C)C=C)=C(O)C=C1OC

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36/37
WGK Germany: 3
RTECS: UB8755000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL80486
Product name: Licochalcone A
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $472
Updated: 2025/07/31

Sigma-Aldrich

Product number: 435800
Product name: Licochalcone-A, Synthetic
Packaging: 10mg
Price: $114
Updated: 2025/07/31

Sigma-Aldrich

Product number: 435800
Product name: Licochalcone-A, Synthetic
Packaging: 50mg
Price: $415
Updated: 2025/07/31

TCI Chemical

Product number: L0261
Product name: Licochalcone A
Packaging: 5MG
Price: $98
Updated: 2025/07/31

TCI Chemical

Product number: L0261
Product name: Licochalcone A
Packaging: 25MG
Price: $293
Updated: 2025/07/31

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LICOCHALCONE-A Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of licorice.

Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Definition

ChEBI: Licochalcone A is a member of chalcones.

General Description

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Preparation Products And Raw materials

Raw materials

Preparation Products

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LICOCHALCONE-A Suppliers

China 305 Europe 1 Germany 1 India 3 Japan 1 South Korea 1 Switzerland 2 United Kingdom 3 United States 22 USA 1 Global 340

Chengdu Nakeli Biotechnology Co., Ltd.

Tel: 028-61983833 19138982515
Fax: 3265827856
Email: 3265827856@qq.com
Country: China
ProdList: 1581
Advantage: 58

Nanjing Peiwill Biotechnology Co.,Ltd.

Tel: 025-57027729 15850702895
Fax: 025-57027729
Email: 15850702895@163.com
Country: China
ProdList: 87
Advantage: 55

Nanjing puyi biotechnology co., LTD

Tel: 13814510036
Email: 927565933@qq.com
Country: China
ProdList: 1933
Advantage: 58

Nanjing Yuanzhi Biotechnology Co. Ltd.

Tel: 15805159960
Email: 1211550495@qq.com
Country: China
ProdList: 1796
Advantage: 58

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Tel: 025-84430028 13815430202
Email: sale02@cqherb.com
Country: China
ProdList: 294
Advantage: 59

Nanjing Bencao Yikang Biotechnology Co., Ltd

Tel: 025-69790911 18362932668
Email: 522593521@qq.com
Country: China
ProdList: 1163
Advantage: 58

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd

Tel: 13186333400
Email: cuichengbio@163.com
Country: China
ProdList: 4846
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

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View Lastest Price from LICOCHALCONE-A manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Licochalcone A 58749-22-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 5% 10% 50% 98% 99%
Supply Ability: 1000 kg
Release date: 2025-10-22

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Licochalcone A 58749-22-7
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-10

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Licochalcone a Powder 58749-22-7
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-18

58749-22-7, LICOCHALCONE-ARelated Search:

koumine DihydrocurcuMin Cianidanol Swertiamarine CASTICIN Phloretin Licochalcone B LICOCHALCONEC Glabridin Liguiritigenin-7-O-D-apiosyl-4’-O-D-glucoside Isoliquiritigenin LIQUIRITIGENIN LIQUIRITIN(SH) ISOLIQUIRITIN isoliquiritin apioside LICOCHALCONE-A 2,4,4'-TRIHYDROXY BENZALACETOPHENONE 4,4'-DIHYDROXY-2-METHOXYCHALCONE

LICOCHALCONE-A

(E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE

4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone

2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-

(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

7-Dimethoxycoumarin

Licochalcone A, >=98%

Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A

Licochalcone A, >99%

CS-919

Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem

(E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Licocgalcone-A

(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one

4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone

(2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Glycyrrhiza chalcone A

Licorice Chalcone A

Licoricchalcone A

Licochalcone A (10mg)

Licochalcone A-RM

Licochalcone a Powder

Licochalcone A, 10 mM in DMSO

58749-22-7

28749-22-7

The group of Liquorice

sy

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract