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LICOCHALCONE-A

Product Name
LICOCHALCONE-A
CAS No.
58749-22-7
Chemical Name
LICOCHALCONE-A
Synonyms
CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Glycyrrhiza chalcone A;4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
CBNumber
CB5114580
Molecular Formula
C21H22O4
Formula Weight
338.4
MOL File
58749-22-7.mol
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LICOCHALCONE-A Property

Melting point:
100°
Boiling point:
532.6±50.0 °C(Predicted)
Density 
1.171±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka
7.82±0.15(Predicted)
form 
Yellow solid
color 
Yellow-orange
BRN 
4534154
InChIKey
KAZSKMJFUPEHHW-DHZHZOJOSA-N
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36/37
WGK Germany 
3
RTECS 
UB8755000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80486
Product name
Licochalcone A
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$595
Updated
2024/03/01
Sigma-Aldrich
Product number
435800
Product name
Licochalcone-A, Synthetic
Packaging
10mg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
435800
Product name
Licochalcone-A, Synthetic
Packaging
50mg
Price
$404
Updated
2024/03/01
Cayman Chemical
Product number
11853
Product name
Licochalcone A
Purity
≥95%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
11853
Product name
Licochalcone A
Purity
≥95%
Packaging
10mg
Price
$93
Updated
2024/03/01
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LICOCHALCONE-A Chemical Properties,Usage,Production

Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Definition

ChEBI: Licochalcone A is a member of chalcones.

General Description

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Preparation Products And Raw materials

Raw materials

Preparation Products

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LICOCHALCONE-A Suppliers

Nanjing Peiwill Biotechnology Co.,Ltd.
Tel
025-57027729 15850702895
Fax
025-57027729
Email
15850702895@163.com
Country
China
ProdList
73
Advantage
55
Nanjing puyi biotechnology co., LTD
Tel
025-58886740; 13814510036
Email
927565933@qq.com
Country
China
ProdList
1930
Advantage
58
Nanjing Yuanzhi Biotechnology Co. Ltd.
Tel
15805159960
Email
1211550495@qq.com
Country
China
ProdList
1793
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Tel
025-84430028 13815430202
Email
sale02@cqherb.com
Country
China
ProdList
279
Advantage
59
Chengdu Chenlv Herb Co., Ltd.
Tel
028-88523492 15528171243
Email
chenrongpharma@126.com
Country
China
ProdList
124
Advantage
58
Nanjing Bencao Yikang Biotechnology Co., Ltd
Tel
+86-025-69790911 18362932668
Email
522593521@qq.com
Country
China
ProdList
1163
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
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View Lastest Price from LICOCHALCONE-A manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
LICOCHALCONE-A 58749-22-7
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
≥98%
Supply Ability
20tons
Release date
2024-01-03
Shaanxi Haibo Biotechnology Co., Ltd
Product
Licochalcone A 58749-22-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-09-07
Hebei Duling International Trade Co. LTD
Product
LICOCHALCONE-A 58749-22-7
Price
US $100.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100 tons
Release date
2023-01-11

58749-22-7, LICOCHALCONE-ARelated Search:


  • LICOCHALCONE-A
  • (E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE
  • 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
  • 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-
  • (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • 7-Dimethoxycoumarin
  • Licochalcone A, >=98%
  • Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A
  • Licochalcone A, >99%
  • CS-919
  • Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem
  • (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Licocgalcone-A
  • (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
  • 4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone
  • (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
  • Glycyrrhiza chalcone A
  • Licorice Chalcone A
  • Licoricchalcone A
  • 58749-22-7
  • The group of Liquorice
  • sy
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract