LICOCHALCONE-A

ChemicalBook > CAS DataBase List > LICOCHALCONE-A

Product Name: LICOCHALCONE-A
CAS No.: 58749-22-7
Chemical Name: LICOCHALCONE-A
Synonyms: CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%;Glycyrrhiza chalcone A;4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone
CBNumber: CB5114580
Molecular Formula: C21H22O4
Formula Weight: 338.4
MOL File: 58749-22-7.mol

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LICOCHALCONE-A Property

Melting point:: 100°
Boiling point:: 532.6±50.0 °C(Predicted)
Density: 1.171±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM)
DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM)
Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
pka: 7.82±0.15(Predicted)
form: Yellow solid
color: Yellow-orange
BRN: 4534154
InChIKey: KAZSKMJFUPEHHW-DHZHZOJOSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36/37
WGK Germany: 3
RTECS: UB8755000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL80486
Product name: Licochalcone A
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $595
Updated: 2024/03/01

Sigma-Aldrich

Product number: 435800
Product name: Licochalcone-A, Synthetic
Packaging: 10mg
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: 435800
Product name: Licochalcone-A, Synthetic
Packaging: 50mg
Price: $404
Updated: 2024/03/01

Cayman Chemical

Product number: 11853
Product name: Licochalcone A
Purity: ≥95%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 11853
Product name: Licochalcone A
Purity: ≥95%
Packaging: 10mg
Price: $93
Updated: 2024/03/01

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LICOCHALCONE-A Chemical Properties,Usage,Production

Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Definition

ChEBI: Licochalcone A is a member of chalcones.

General Description

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

Biochem/physiol Actions

Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.

LICOCHALCONE-A Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from LICOCHALCONE-A manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: LICOCHALCONE-A 58749-22-7
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2024-01-03

Shaanxi Haibo Biotechnology Co., Ltd

Product: Licochalcone A 58749-22-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-09-07

Hebei Duling International Trade Co. LTD

Product: LICOCHALCONE-A 58749-22-7
Price: US $100.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100 tons
Release date: 2023-01-11

58749-22-7, LICOCHALCONE-ARelated Search:

koumine DihydrocurcuMin Cianidanol Swertiamarine CASTICIN Phloretin Licochalcone B LICOCHALCONEC Glabridin Liguiritigenin-7-O-D-apiosyl-4’-O-D-glucoside Isoliquiritigenin LIQUIRITIGENIN LIQUIRITIN(SH) ISOLIQUIRITIN isoliquiritin apioside LICOCHALCONE-A 2,4,4'-TRIHYDROXY BENZALACETOPHENONE 4,4'-DIHYDROXY-2-METHOXYCHALCONE

LICOCHALCONE-A

(E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE

4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone

2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-

(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

7-Dimethoxycoumarin

Licochalcone A, >=98%

Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A

Licochalcone A, >99%

CS-919

Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem

(E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Licocgalcone-A

(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one

4,4'-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone

(2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Glycyrrhiza chalcone A

Licorice Chalcone A

Licoricchalcone A

58749-22-7

The group of Liquorice

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract