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(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL

Product Name
(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL
CAS No.
79868-79-4
Chemical Name
(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL
Synonyms
(R)-1,1,2-Triphenyl-2-aminoethanol;(2R)-1,1,2-Triphenyl-2-aminoethanol;(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL;R-N-Boc-2-Amino-1,1-diphenyl-1-propanol;(S)-2-Amino-1,1-diphenyl-1-propanol,99%e.e.;Benzeneethanol, β-amino-α,α-diphenyl-, (βR)-;Benzeneethanol, b-amino-a,a-diphenyl-, (bR)-;(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL USP/EP/BP;(R)-2-Amino-1,1,2-triphenylethanol(R)-2-Amino-1,1,2-triphenylethanol
CBNumber
CB0379142
Molecular Formula
C20H19NO
Formula Weight
289.37
MOL File
79868-79-4.mol
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(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL Property

Melting point:
130-131℃
Boiling point:
456.0±40.0 °C(Predicted)
Density 
1.162±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
10.89±0.50(Predicted)
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Safety

HS Code 
2922190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories
Product number
4656-1-RJ
Product name
(R)-2-(+)-Amino-1,1,2-triphenylethanol
Packaging
100mg
Price
$184
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140896
Product name
(R)-2-Amino-1,1,2-triphenylethanol
Packaging
250mg
Price
$245
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-1-RJ
Product name
(R)-2-(+)-Amino-1,1,2-triphenylethanol
Packaging
250mg
Price
$314
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0013249
Product name
(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL
Purity
95.00%
Packaging
250MG
Price
$396.9
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140896
Product name
(R)-2-Amino-1,1,2-triphenylethanol
Packaging
500mg
Price
$430
Updated
2021/12/16
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(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL Chemical Properties,Usage,Production

Synthesis

1395342-04-7

60539-17-5

Amino alcohol (S,R)-3n (64 mg, 0.15 mmol) was used as a raw material, and Pd(OH)2 (16 mg, 0.023 mmol, 20% Pd (dry basis) loaded on carbon, containing ~50% water) was mixed in a solvent mixture of acetic acid/ dichloromethane/ methanol (0.15 mL/0.45 mL/1.5 mL) under hydrogen atmosphere (1 atm) at 30 °C with stirring overnight. Upon completion of the reaction, 1.0 M NaOH solution was added to the reaction mixture, at which time a white solid precipitated. The solid was removed by filtration and the filtrate was extracted with dichloromethane. The combined organic phases were washed sequentially with water, brine and dried with anhydrous Na2SO4. The solvent was removed by concentration under reduced pressure and the residue was purified by silica gel column chromatography (eluent: methanol/dichloromethane = 1/50) to afford amino alcohol (R)-4 as a white solid (28 mg, 66% yield). The enantiomeric excess (ee) of the product was 100%. Specific optical rotation [α]D20 was +246.4 (c 1.0, CHCl3).1H NMR (400 MHz, CDCl3) δ 1.60 (broad peak, 2H), 4.68 (broad peak, 1H), 5.00 (single peak, 1H), 6.99-7.05 (multiple peaks, 3H), 7.10-7.13 (multiple peaks, 7H), 7.27 (triple peak) J=7.2 Hz, 1H), 7.39 (triple peaks, J=8.0 Hz, 2H), 7.74 (double peaks, J=7.6 Hz, 2H); 13C NMR (100 MHz, CDCl3) δ 61.72, 79.51, 125.98, 126.19, 126.50, 126.98, 127.19, 127.32 123.39, 128.50, 128.62, 140.02, 143.83, 146.46. The spectral data were in agreement with those reported in the literature. HPLC analysis (chiral column Chiralpak OD-H, mobile phase: hexane/isopropanol = 90/10, flow rate = 1.0 mL/min, detection wavelength λ = 214 nm): retention time of main peak tmajor=16.31 min.

References

[1] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5084 - 5087

(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL Suppliers

China 52 India 1 Spain 1 United Kingdom 5 United States 5 Global 64
Enantia, S.L.
Tel
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Fax
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Email
info@enantia.com
Country
Spain
ProdList
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View Lastest Price from (R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL manufacturers

Career Henan Chemical Co
Product
(R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL 79868-79-4
Price
US $2.00/KG
Min. Order
1g
Purity
98%MIN
Supply Ability
ASK
Release date
2020-01-09

79868-79-4, (R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOLRelated Search:

Ethanol (S)-1,2,2-TRIPHENYLETHYLAMINE (1R,2R)-(+)-2-AMINO-1,2-DIPHENYLETHANOL (R)-(-)-2-PIPERIDINO-1,1,2-TRIPHENYLETHANOL (R)-4,5,5-TRIPHENYL-2-OXAZOLIDINONE (R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL (R)-2-AMINO-1,2-DIPHENYL-1-PROPANOL (R)-(+)-N-CARBOMETHOXY-2-AMINO-1,1,2-TRIPHENYLETHANOL

  • (R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL
  • (2R)-1,1,2-Triphenyl-2-aminoethanol
  • (R)-1,1,2-Triphenyl-2-aminoethanol
  • R-N-Boc-2-Amino-1,1-diphenyl-1-propanol
  • (R)-2-Amino-1,1,2-triphenylethanol(R)-2-Amino-1,1,2-triphenylethanol
  • (S)-2-Amino-1,1-diphenyl-1-propanol,99%e.e.
  • Benzeneethanol, β-amino-α,α-diphenyl-, (βR)-
  • (R)-2-(+)-AMINO-1,1,2-TRIPHENYLETHANOL USP/EP/BP
  • Benzeneethanol, b-amino-a,a-diphenyl-, (bR)-
  • 79868-79-4