BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE

Product Name: BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE
CAS No.: 125-51-9
Chemical Name: BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE
Synonyms: qpb;jb-323;piptal;Piptalake;Pipenzolate;PIPENZOLATE BROMIDE;pipenzolatemethobromide;PIPENZOLATE BROMIDE(SH);pipenzolatemethylbromide;XEDCWWFPZMHXCM-UHFFFAOYSA-M
CBNumber: CB0381093
Molecular Formula: C22H28BrNO3
Formula Weight: 434.37
MOL File: 125-51-9.mol

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BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Property

Melting point:: 179-180°
form: powder
color: white

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: TN5425000
Toxicity: LD50 oral in rat: 916mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P479853
Product name: Piptalake
Packaging: 100mg
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003871
Product name: PIPENZOLATE BROMIDE
Purity: 95.00%
Packaging: 10G
Price: $1275.81
Updated: 2021/12/16

AK Scientific

Product number: 2658AH
Product name: Pipenzolatebromide
Packaging: 1g
Price: $2625
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003871
Product name: PIPENZOLATE BROMIDE
Purity: 95.00%
Packaging: 50G
Price: $2677.14
Updated: 2021/12/16

Crysdot

Product number: CD31004085
Product name: Pipenzolatebromide
Purity: 98+%
Packaging: 100mg
Price: $49
Updated: 2021/12/16

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BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Chemical Properties,Usage,Production

Originator

Piptal ,Merrell National ,US ,1955

Uses

Piptalake is used in the treatment with copper-tolylterpyridine and platinum-tolylterpyridine that targets telomeres and telomerase for regulation of chromosome mis-segregation rates for cancer therapy.

Uses

antispasmodic

Manufacturing Process

N-ethyl-3-chloropiperidine was prepared according to the method of Fuson and Zirkle described in Volume 70, J. Am. Chem. Soc., p 2760. 12.0 g (0.081 mol) of N-ethyl-3-chloropiperidine was mixed with 18.6 g (0.081 mol) of benzilic acid and 80 cc of anhydrous isopropyl alcohol as a solvent. The mixture was refluxed for 72 hours. The solution was then filtered and concentrated at 30 mm of mercury. The concentrate was dissolved in water, acidified with hydrochloric acid and extracted with ether to remove theThe aqueous layer was neutralized with sodium bicarbonate and the product was extracted with ether. The ethereal solution of the product was dried with potassium carbonate, the ether was removed by distillation and the residue was distilled at 0.12 to 0.18 mm of mercury, the BP being 194° to 198°C. A yield of 16.5 g (60% of theoretical) of N-ethyl-3-piperidyl-benzilate was obtained.
34 g (0.1 mol) of the basic ester is dissolved in 75 cc of isopropyl alcohol and treated with 9.5 g (0.1 mol) of methyl bromide. The mixture is allowed to stand at room temperature until precipitation is complete. The product is removed by filtration and washed with isopropyl alcohol, yield 33 g, MP 175° to 177°C. On recrystallization from isopropyl alcohol, the MP was raised to 179° to 180°C dec.

brand name

Piptal (Marion Merrell Dow).

Therapeutic Function

Spasmolytic

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE Suppliers

China 19 Germany 1 India 2 Switzerland 1 United Kingdom 1 United States 9 Global 33

Shanghai Hanhong Scientific Co.,Ltd.

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Musechem

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AFINE CHEMICALS LIMITED

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Jinan Ruisi Pharmaceutical Technology Co., LTD

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Shanghai Jiegu Biotechnology Co., Ltd.

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Shaanxi Dideu Medichem Co. Ltd

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125-51-9, BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDERelated Search:

Ethyl 2-hydroxyisobutyrate Methyl DL-mandelate 3-ETHOXYPIPERIDINE (R)-(-)-Methyl mandelate Methyl benzilate (R)-(-)-2-HYDROXY-2-PHENYLPROPIONIC ACID BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE PIPERIDOLATE Methyl 2-hydroxyisobutyrate Adiphenine hydrochloride 3-METHOXYPIPERIDINE L-(+)-MANDELIC ACID ETHYL ESTER Benzilic acid (S)-(+)-2-HYDROXY-2-PHENYLPROPIONIC ACID ACETYLCHOLINE BROMIDE Benactyzine 1-ETHYL-3-HYDROXYPIPERIDINE ISOPROPYL (S)-(-)-LACTATE

PIPENZOLATE BROMIDE

1-ethyl-3-hydroxy-1-methyl-piperidiniumbromidebenzilate

1-Ethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-methyl-1-piperidinium Bromide

1-ethyl-3-piperidylbenzilatemethylbromide

benzilicacid,1-ethyl-3-piperidylestermethylbromide

benzilicacid,esterwith1-ethyl-3-hydroxy-1-methylpiperidiniumbromide

jb-323

n-ethyl-3-piperidylbenzilatemethobromide

pipenzolatemethobromide

pipenzolatemethylbromide

XEDCWWFPZMHXCM-UHFFFAOYSA-M

piperidinium,1-ethyl-3-hydroxy-1-methyl-,bromide,benzilate

piptal

qpb

BENZILIC ACID 1-ETHYLPIPERIDIN-3-YL ESTER METHOBROMIDE

3-benziloyloxy-1-ethyl-1-methylpiperidinium bromide

pipenzolate bromide sigmaultra

Pipenzolate

PIPENZOLATEBROMIDE,ULTRAPURE

PIPENZOLATE BROMIDE(SH)

1-Ethyl-3-(2-hydroxy-2,2-diphenylacetoxy)-1-Methylpiperidin-1-iuM broMide

Piptalake

Pipenzolate BromideQ: What is Pipenzolate Bromide Q: What is the CAS Number of Pipenzolate Bromide Q: What is the storage condition of Pipenzolate Bromide

Piperidinium, 1-ethyl-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-, bromide (1:1)

125-51-9

C22H28BrNO3

C22H28NO3Br

Building Blocks

Heterocyclic Building Blocks

Piperidines

PIPTAL

Inhibitors

Building Blocks

C16 to C36

Chemical Synthesis

Heterocyclic Building Blocks

Piperidines